Hematoporphyrin derivative and method of preparation and purification
First Claim
1. A substance effective for treatment of tumor cells having a fluorescent emission between 640 and 650 nm and capable of preferentially localizing in and being retained in tumor cells over normal cells, the substance selected from the group consisting of:
- ##STR2## and its isomers;
##STR3## and its isomers;
II. the alkali metal salts thereof; and
mixtures thereof;
IV. the alkali metal salts thereof; and
mixtures thereof;
1 Assignment
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Accused Products
Abstract
A substance effective for treatment of tumors having a fluorescent emission between 640 nm and 650 nm capable of preferentially localizing in and being retained in tumor cells, the substance being a product of esterification of hematorporphyrin with a chlorin and a process for destruction of tumor cells in a patient involving the steps of:
(a) injecting a solution containing the substance into a patient;
(b) allowing the substance to accumulate in the tumor cells; and
(c) irradiating the tumor site with light at a predetermined intensity and a wavelength between about 640 nm and about 650 nm.
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Citations
4 Claims
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1. A substance effective for treatment of tumor cells having a fluorescent emission between 640 and 650 nm and capable of preferentially localizing in and being retained in tumor cells over normal cells, the substance selected from the group consisting of:
- ##STR2## and its isomers;
##STR3## and its isomers;
II. the alkali metal salts thereof; and
mixtures thereof;IV. the alkali metal salts thereof; and
mixtures thereof; - View Dependent Claims (2, 3, 4)
- ##STR2## and its isomers;
Specification