Electrocardiogram enhancement system and method

• US 4,862,897 A
• Filed: 12/31/1986
• Issued: 09/05/1989
• Est. Priority Date: 11/05/1985
• Status: Expired due to Fees

• Current Assignee: Sound Enhancement Systems Incorporated
• Original Assignee: Sound Enhancement Systems Incorporated
• Inventors: Eisenberg, Michael A., Eisenberg, Lawrence
• Primary Examiner(s): Picard, Leo P.
• Application Number:
  US06/948,195
• Time in Patent Office: 979 Days
• Field of Search: 128/660-663, 128/715, 128/773, 128/696, 128/710, 128/701, 381/67, 381/98, 364/417
• US Class Current: 600/528
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/308 for electrocardiography [ECG]
• CPC Class Codes: A61B 5/333 Recording apparatus specially adapted therefor
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R
• CPC Class Codes: Y10S 128/925 Neural network

Abstract

An electrocardiogram enhancement system and apparatus is provided. Small amplitude, high frequency notches associated with myocardial disease and arrhythmias can be recorded by conventional chart recorders. In addition, the notches are clearly visible in the recorded waveform for visual detection and analysis of the notches by medical personnel.

In the system of the present invention electrocardiogram signals having small amplitude, high frequency notches are enhanced; first, by selectively amplifying the notches while keeping the amplitude of the remainder of the waveform constant and, second, by uniformly expanding the signal in the time domain wherein the inter-component frequency and inter-component phase relationships are maintained.

Claims

1. A method for enhancing an electrocardiogram signal having frequency, low amplitude notches that are difficult to visually detect within an electrocardiogram signal waveform and that have frequencies above the signal recording bandwidth of a conventional chart recorder, said signal having a plurality of frequency components, each frequency component having a frequency, phase and amplitude, the frequencies of the frequency components comprising a first inter-component frequency relationship and the phases of the frequency components comprising a first inter-component phase relationship said enhancement method comprising the steps of:

selectively amplifying frequency components representing the notches relative to other frequency components in the electrocardiogram signal; and

expanding said electrocardiogram signal including the amplified frequency components in time scale by a time scale expansion factor, frequency components representing said expanded signal having a second intercomponent frequency relationship and a second inter-component phase relationship equivalent to said first inter-component frequency relationship and first inter-component phase relationship, said expanded signal having a frequency range within the bandwidth of a conventional chart recorder.

2. The method of claim 1 wherein said expanding of said electrocardiogram signal in the time scale comprises dividing the frequency of each frequency component by a time scale expansion factor.

3. The method of claim 2 wherein said time scale expansion factor is greater than one.

4. The method of claim 1 wherein said selectively amplifying said electrocardiogram signal comprises:

selecting those frequency components of the electrocardiogram signal within a predetermined frequency range and greater than a minimum amplitude value indicative of notches; and

multiplying each of the selected frequency components by an amplification factor.

5. The method of claim 4 wherein said frequency range is greater than 100 up to and including 1200 Hz.

6. The method of claim 4 wherein said minimum amplitude value is determined to exclude high frequency signal noise.

7. The method of claim 6 wherein said minimum amplitude value is greater than 5% of the peak amplitude of notch frequency components.

8. The method of claim 4 wherein the amplification factor is equal to the ratio of a peak amplitude of non-notch frequency components to a peak amplitude of the notch frequency components multiplied by a gain factor.

9. The method of claim 8 where the gain factor ranges from a value greater than zero up to one.

10. The method of claim 1 further comprising:

generating a Fourier transform of the electrocardiogram signal to obtain a frequency spectrum comprising the frequency components representing the electrocardiogram signal; and

generating an inverse Fourier transform of the frequency spectrum after selectively amplifying and expanding the frequency component of the signal.

11. The method of claim 1 further comprising the step of accurately recording the expanded signal and displaying the high frequency, low amplitude notches.

12. A method for enhancing an electrocardiogram signal in a first frequency range having high frequency, low amplitude notches that are difficult to visually detect and analyze within an electrocardiogram signal waveform and that have frequencies above the signal recording bandwidth of a conventional chart recorder, said enhancement method comprising the steps of:

performing a Fourier transform operation upon the electrocardiogram signal whereby a frequency spectrum signal is obtained, said frequency spectrum signal comprising frequency components having an amplitude, frequency, and phase, the frequencies of the frequency components comprising a first inter-component frequency relationship and the phases of the frequency components comprising a first inter-component phase relationship;

selecting frequency components within a predetermined frequency range and greater than a minimum amplitude value that are indicative of notches;

amplifying each of the selected frequency components by an amplification factor;

expanding the frequency spectrum signal in time scale by dividing each frequency component by a time scale expansion factor, frequency components having a second inter-component frequency and second inter-component phase relationship equivalent to said first inter-component frequency and first inter-component phase relationship; and

performing an inverse Fourier transform operation upon the expanded frequency spectrum signal to obtain an enhanced electrocardiogram signal, said enhanced electrocardiogram signal having a frequency range within the signal recording bandwidth of conventional chart recorders.

13. The method of claim 12 wherein said time scale expansion factor is greater than one.

14. The method of claim 12 wherein said amplification factor is a value equal to the ratio of a peak amplitude of non-notch frequency components to a peak amplitude of the notch frequency components multiplied by a gain factor.

15. The method of claim 14 wherein said gain factor ranges from a value greater than zero up to one.

16. The method of claim 12 wherein said frequency range is greater than 100 up to and including 1200 Hz.

17. The method of claim 12 wherein said minimum amplitude value is determined to exclude high frequency signal noise.

18. The method of claim 17 wherein said minimum amplitude value is greater than 5% of the peak value of the notch frequency components.

19. The method of claim 12 further comprising the step of accurately recording the enhanced electrocardiogram waveform and displaying the high frequency, low amplitude notches.

20. Apparatus for enhancing an electrocardiogram signal having high frequency, low amplitude notches that are difficult to visually detect within an electrocardiogram signal waveform and that have frequencies above the signal recording bandwidth of a conventional chart recorder, said signal having a plurality of frequency components, each frequency component having a frequency, phase and amplitude, the frequencies of the frequency components comprising a first inter-component frequency relationship and the phases of the frequency components comprising a first inter-component phase relationship, said apparatus comprising:

means for selectively amplifying frequency components representing the notches relative to other frequency components in the electrocardiogram signal; and

means for expanding said electrocardiogram signal including the amplified frequency components in time scale by a time scale expansion factor, frequency components representing said expanded signal having a second inter-component frequency relationship and second inter-component phase relationship equivalent to said first inter-component frequency relationship and first inter-component phase relationship, said expanded signal being within the bandwidth of a conventional chart recorder, whereby the expanded signal is accurately recorded, and the high frequency, low amplitude notches are made visible

21. The apparatus of claim 20 wherein the means for expanding said electrocardiogram signal in the time scale comprises a means for dividing the frequency of each frequency component by a time scale expansion factor.

22. The apparatus of claim 21 wherein said time scale expansion factor is greater than one.

23. The apparatus of claim 20 wherein the means for selectively amplifying said electrocardiogram signal comprises:

means for selecting frequency components within a predetermined frequency range and greater than a minimum amplitude value indicative of notches; and

means for amplifying each of the selected frequency components by an amplification factor.

24. The apparatus of claim 23 wherein said frequency range is greater than 100 up to and including 1200 Hz.

25. The apparatus of claim 23 wherein said amplitude range excludes high frequency signal noise.

26. The apparatus of claim 25 wherein said minimum amplitude value is equal to 5% of the peak value of the notch frequency components.

27. The apparatus of claim 23 wherein said amplification factor is equal to the ratio of a peak amplitude of non-notch frequency components to a peak amplitude of the notch frequency components multiplied by a gain factor.

28. The apparatus of claim 27 wherein said gain factor ranges from a value greater than zero up to one.

29. The apparatus of claim 20 further comprising:

means for generating a Fourier transform of the electrocardiogram signal to obtain a frequency spectrum comprising the frequency components representing the electrocardiogram signal; and

means for generating an inverse Fourier transform of the frequency spectrum after selectively amplifying and expanding in the time scale the frequency components of the signal.

30. The apparatus of claim 29 wherein the means for generating a Fourier transform, means for selectively amplifying, means for expanding and means for generating an inverse Fourier transform comprises a microprocessor.

31. The apparatus of claim 20 further comprising a means for counting the high frequency notches and a means for displaying said count of notches.

32. The apparatus of claim 31 wherein the means for counting the notches comprises:

means for detecting the beginning and end of a QRS wave of the electrocardiogram signal waveform;

means for calculating the slope of the waveform at a first test point;

means for calculating the slope of the waveform at a second subsequent test point, said second test point being a predetermined time period after said first test point;

means for comparing the slopes of said first and second test points;

means for incrementing a notch counter if the signs of said slopes of said test points are not equal;

means for setting said first test point equal to said second test point wherein the means for calculating the slope of the waveform at the second test point, means for comparing the slopes of said first and second test points and means for incrementing said notch counter continue to operate to sequence until the end of the QRS wave is detected.

33. The apparatus of claim 31 wherein the means for counting the notches comprises:

a threshold detector which generates an output pulse upon detection of those notches of a predetermined minimum amplitude;

means for inputting selected frequency components indicative of notches to the threshold detector; and

a digital counter which counts the output pulses of the threshold detector.

34. The apparatus of claim 20 further comprising a chart recording device for the display of said expanded signal whereby the electrocardiogram signal is accurately recorded and the high frequency, low amplitude notches are visible in the displayed signal.

35. The apparatus of claim 20 further comprising means for accurately recording the expanded signal and means for displaying the high frequency, low amplitude notches.

36. Apparatus for enhancing an electrocardiogram signal in a first frequency range having high frequency, low amplitude notches that are difficult to visually detect and analyze within a electrocardiogram signal waveform and that have frequencies above the signal recording bandwidth of a conventional chart recorder comprising:

means for performing a Fourier transform operation upon the electrocardiogram signal whereby a frequency spectrum signal is obtained, said frequency spectrum signal comprising frequency components having an amplitude, frequency, and phase, the frequencies of the frequency components comprising a first inter-component frequency relationship and the phases of the frequency components comprising a first inter-component phase relationship;

means for selecting frequency components within a predetermined frequency range and greater than a minimum amplitude value that are indicative of notches;

means for amplifying each of the selected frequency components by an amplification factor;

means for expanding the frequency spectrum in time scale by dividing each frequency component by a time scale expansion factor, frequency components having a second inter-component frequency relationship and a second inter-component phase relationship equivalent to said first inter-component frequency relationship and first inter-component phase relationship;

means for performing an inverse Fourier transform operation upon the expanded frequency spectrum signal to obtain an enhanced electrocardiogram signal, said enhanced electrocardiogram signal having a frequency range within the bandwidth of conventional chart recorders; and

chart recording means for display of the expanded signal where in the high frequency, low amplitude notches are visible within the displayed signal.

37. The apparatus of claim 36 wherein the means for performing a Fourier transform, means for selecting frequency components, means for amplifying the selected frequency components, means for expanding the frequency spectrum and means for performing an inverse Fourier transform comprises a microprocessor.

38. The apparatus of claim 36 wherein said time scale expansion factor is greater than one.

39. The apparatus of claim 36 wherein said amplification factor is equal to the ratio of a peak amplitude of non-notch frequency components to a peak amplitude of the notch frequency components multiplied by a gain factor.

40. The apparatus of claim 39 wherein said gain factor ranges from a value greater than zero up to one.

41. The apparatus of claim 36 wherein said frequency range is greater than 100 up to and including 1200 Hz.

42. The apparatus of claim 36 wherein said minimum amplitude value excludes high frequency signal noise.

43. The apparatus of claim 42 wherein said minimum amplitude value is 5% of the peak value of the notch frequency components.

44. A method for enhancing an electrocardiogram signal having high frequency, low amplitude notches that have frequencies above 100 Hz and are difficult to visually detect within an electrocardiogram signal waveform, said signal having a plurality of frequency components, each frequency component having a frequency, phase and amplitude, said enhancement method comprising the steps of:

amplifying the frequency components above 100 Hz relative to other frequency components in the electrocardiogram signal by an amplification factor; and

then

expanding said electrocardiogram signal including the amplified frequency components in time scale by a time scale expansion factor to produce an expanded signal, said expanded signal having frequency components in which the frequencies are those of the frequency components of the electrocardiogram signal divided by the time scale expansion factor, said expanded signal having a frequency range within the bandwidth of a conventional chart recorder.

45. The method for enhancing an electrocardiogram signal of claim 44 wherein said frequencies of the frequency components of the electrocardiogram signal comprise a first inter-component relationship and the phases of the frequency components comprise a first inter-component phase relationship and frequencies of the frequency components of the expanded signal comprise a second inter-component frequency relationship equivalent to said first inter-component frequency relationship and the phases of the frequency components comprise a second inter-component phase relationship equivalent to said first inter-component phase relationship.

46. The method for enhancing an electrocardiogram signal of claim 44 further comprising:

generating a Fourier transform of the electrocardiogram signal to obtain a frequency spectrum comprising the frequency components representing the electrocardiogram signal; and

generating an inverse Fourier transform of the frequency spectrum after amplifying and expanding the signal.

47. The method of claim 44 further comprising displaying the high frequency, low amplitude notches.

48. Apparatus for enhancing an electrocardiogram signal having high frequency, low amplitude notches that have frequencies above 100 Hz and are above the signal recording bandwidth of a conventional chart recorder and difficult to visually detect within an electrocardiogram signal waveform, said signal being within a first frequency range and having a plurality of frequency components, each frequency component having a frequency, phase and amplitude, said apparatus comprising:

means for amplifying the frequency components above 100 Hz relative to other frequency components in the electrocardiogram signal by an amplification factor; and

means for expanding said electrocardiogram signal including the amplified frequency components in time scale by a time scale expansion factor to produce an expanded signal, said expanded signal having frequency components in which the frequencies are those of the frequency components of the electrocardiogram signal divided by the time scale expansion factor, said expanded signal having a frequency range within the bandwidth of a conventional chart recorder.

49. The apparatus of claim 48 wherein said frequencies of the frequency components of the electrocardiogram signal comprise a first inter-component frequency relationship and the phases of the frequency components comprise a first inter-component phase relationship and frequencies of the frequency components of the expanded signal comprise a second inter-component frequency relationship equivalent to said first inter-component frequency relationship and the phases oaf the frequency components comprise a second inter-component phase relationship equivalent to said first inter-component phase relationship.

50. The apparatus of claim 48 further comprising:

means for generating a Fourier transform of the electrocardiogram signal to obtain a frequency spectrum comprising frequency components representing the electrocardiogram signal; and

means for generating an inverse Fourier transform of the frequency spectrum after amplifying and expanding the signal.

51. The apparatus of claim 48 further comprising a chart recording device for the display of said expanded signal whereby the electrocardiogram signal is accurately recorded and the high frequency, low amplitude notches are visible in the displayed signal.

52. The apparatus of claim 48 further comprising means for displaying the high frequency, low amplitude notches.