Sterilizing method

• US 4,867,739 A
• Filed: 06/17/1985
• Issued: 09/19/1989
• Est. Priority Date: 03/26/1982
• Status: Expired due to Term

• Current Assignee: Kawasumi Laboratories Incorporated (Sumitomo Bakelite Company Limited)
• Original Assignee: Kawasumi Laboratories Incorporated (Sumitomo Bakelite Company Limited)
• Inventors: Kawano, Yasuhiro
• Primary Examiner(s): ROSENBAUM, C FRED
• Application Number:
  US06/745,658
• Time in Patent Office: 1,555 Days
• Field of Search: 604/4-10, 604/264, 604/247, 604/250, 604/905, 128/DIG. 3, 422/44-48, 422/52, 210/321.2
• US Class Current: 604/5.04
• CPC Class Codes: A61L 2/07 Steam
• CPC Class Codes: A61M 1/3643 Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 Mode of operation
• CPC Class Codes: A61M 39/221 Frangible or pierceable closures within tubing A61M39/14 takes precedence; frangible closures for containers A61J1/14
• CPC Class Codes: B01D 2321/32 By heating or pyrolysis
• CPC Class Codes: B01D 65/022 Membrane sterilisation
• CPC Class Codes: Y10S 604/905 Aseptic connectors or couplings, e.g. frangible, piercable

Abstract

A humors processing device is such as an artificial kidney, artificial liver or others. The device is connected with a humors circulating line which is provided with bags supporting physiological saline solution and with communicating mechanisms at appropriate portions of the same, and the communicating mechanism is ready for opening by finger pressure.

Claims

1. A sterilization method for a blood processing device which circulates blood externally of a human body and removes waste material from the blood, the method comprising the steps of:

providing a blood processor having an inlet and an outlet;

connecting a blood inlet line and a blood outlet line to said blood processor inlet and outlet, respectively;

connecting a branched tube to said blood inlet line;

filling both said blood inlet line and said blood outlet line and also said blood processor and said branched tube with a liquid harmless to the human body;

subjecting said filled blood inlet line and blood outlet line and blood processor to an autoclave sterilization in a saturated steam so that said liquid in said inlet and outlet line and said blood processor is heated whereby said inlet and outlet line and said blood processor are sterilized;

connecting a bag filled with physiological saline solution to said branched tube using a finger pressure openable communicating mechanism for establishing and interrupting communication between said bag and said branched tube;

connecting a waste bag to said blood outlet using another communicating mechanism; and

causing the saline solution to flow from said bag filled with solution by opening said communicating mechanism, thereby forcing the liquid in said blood inlet line, said blood processor and said blood outlet line into said waste bag.

2. A method as defined in claim 1;

and further comprising the step of connecting a preparatory tube having an introducing needle at its one end, to said branched tube at its other end.

3. A method as defined in claim 2, wherein said preparatory tube connecting step includes connecting said preparatory tube to said branched tube by a communicating mechanism openable by finger pressure for establishing and interrupting communication.

4. A method as defined in claim 1;

and further comprising the step of connecting a plurality of branched line tubes to said blood inlet line and said blood outlet line by communicating mechanisms openable by finger pressure.

5. A method as defined in claim 4, wherein said step of connecting a plurality of branched line tubes includes connecting a heparin injection line to said blood inlet line.

6. A method as defined in claim 4, wherein said step of connecting a plurality of branched line tubes includes connecting a level adjusting line.

7. A method as defined in claim 4, wherein said step of connecting a plurality of branched line tubes includes connecting a pressure monitoring line to said blood outlet line.

8. A method as defined in claim 4, wherein said step of connecting a plurality of branched line tubes includes connecting a protamine line.

9. A method as defined in claim 1, wherein said waste bag connecting step and said bag connecting step include connecting with a communicating mechanism having a flexible communicating tube and a tube of hard property placed within said flexible communicating tube, said hard tube being formed with a thin film portion.

10. A method as defined in claim 1, wherein said waste bag connecting step and said bag connecting step include connecting with a communicating mechanism having a flexible communicating tube and a communicating piece adapted under pressure for interrupting a passage within said communicating tube.

11. A method as defined in claim 1, wherein said saline filled bag connecting step includes connecting a bag made of a soft synthetic resin.

12. A method as defined in claim 1, wherein said waste solution bag connecting step includes connecting a waste solution bag made of a soft synthetic resin.

13. A method as defined in claim 1, wherein said waste solution bag connecting step includes detachably connecting said waste solution bag to said blood outlet line.