Disposable cassette for a medication infusion system

• US 4,872,813 A
• Filed: 12/01/1987
• Issued: 10/10/1989
• Est. Priority Date: 12/01/1987
• Status: Expired due to Term

• Current Assignee: Cardinal Health 303 Incorporated (Cardinal Health, Inc.)
• Original Assignee: Pacesetter Infusion, Ltd. (Siemens AG)
• Inventors: Gorton, Lanny A., Pelmulder, John P.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Szczecina, Jr., Eugene L.
• Application Number:
  US07/127,333
• Time in Patent Office: 679 Days
• Field of Search: 47/63, 47/360, 47/362, 47/395, 47/313, 47/410, 47/415, 47/435, 47/479, 47/510, 604/65-67, 604/151-155, 128/DIG. 12, 128/DIG. 13
• US Class Current: 417/63
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 5/14216 Reciprocating piston type

Abstract

A disposable cassette containing a fluid pump for use with a main unit including apparatus for driving the pump is disclosed which cassette utilized a piston-type pump in conjunction with active valves to pump fluid. The inlet and outlet channels in the cassette are formed by a diaphragm covering open channels in the cassette body, and the same diaphragm is used to form the active valves, which are actuated by valve actuators in the main pump unit. Additional features of the cassette include an air trap upstream from the pump, and an integral clamp which allows priming of the cassette.

Claims

1. A disposable cassette for use with a medication infusion system, comprising:

a cassette body having an upper surface, said cassette body including a cylinder disposed below the upper surface of said cassette, one end of said cylinder being sealingly attached to the bottom of said upper surface, the other end of said cylinder being open, said upper surface of said cassette body having disposed therein first, second, and third apertures extending therethrough, said second aperture being in communication with the interior of said cylinder at said on end thereof;

piston means located in said cylinder for varying the fluid volume contained in said cylinder by alternately drawing fluid into said cylinder through said second aperture and forcing fluid out of said cylinder through said second aperture;

an inlet passageway recessed into said upper surface of said cassette body, said inlet passageway being open on the top side of said upper surface, one end of said inlet passageway being in fluid communication with said first aperture through which fluid is supplied to sad inlet passageway, the other end of said inlet passageway being located near to said second aperture;

an outlet passageway recessed into said upper surface of said cassette body, said outlet passageway being open on the top side of said upper surface, one end of said outlet passageway being located near to said second aperture, the other end of said outlet passageway being in fluid communication with said third aperture through which fluid is removed from said outlet passageway;

diaphragm means for sealing the open top sides of said inlet and outlet passageways; and

flexible, resilient domed valve means for forming a cavity over a portion of said upper surface of said cassette body including said other end of said inlet passageway, said second aperture, and said one end of said outlet passageway, said cavity being in fluid communication with said inlet passageway, said second aperture leading to said cylinder, and said outlet passageway, said valve means being selectively deformable to prevent the flow of fluids between said inlet passageway and said second aperture, said valve means also being selectively deformable to prevent the flow of fluids between said second aperture and said outlet passageway.

2. A disposable cassette as defined in claim 1, wherein said cassette body is of one-piece, molded construction.

3. A disposable cassette as defined in claim 1, additionally comprising:

a bubble trap disposed below the upper surface of said cassette body.

4. A disposable cassette as defined in claim 3, wherein said bubble trap comprises:

a bubble chamber disposed below the upper surface of said cassette body, said bubble chamber being open on the bottom side thereof;

a siphon tube located in said bubble chamber extending from the bottom of said upper surface nearly to the bottom of said bubble chamber, said siphon tube containing therein a passageway which is open on the bottom of said siphon tube and communicates with said first aperture on the top of said siphon tube; and

a bubble chamber cap for sealing the open bottom of said bubble chamber, said bubble chamber cap including an inlet tube extending up into said bubble chamber from the bottom thereof above the bottom of said siphon tube.

5. A disposable cassette as defined in claim 1, additionally comprising:

a slightly raised border on said upper surface of said cassette body which completely surrounds said inlet passageway, said second aperture, and said outlet passageway, said slightly raised border being used for sealing purposes in cooperation with said diaphragm means.

6. A disposable cassette as defined in claim 5, wherein said slightly raised border closely surrounds the edges of said inlet and outlet passageways, said slightly raised border including a rectangular portion spaced away from and around said other end of said inlet passageway, said second aperture, and said one end of said outlet passageway, said rectangular portion being broken only at the locations said inlet passageway and said outlet passageway extend out of said rectangular portion.

7. A disposable cassette as defined in claim 5, additionally comprising:

a first raised segment located intermediate said other end of said inlet passageway and said second aperture, said first raised segment being located below said domed valve means and being wider than said cavity, said first raised segment cooperating with said valve means to selectively prevent the flow of fluids between said inlet passageway and said second aperture; and

a second raised segment located intermediate said one end of said outlet passageway and said second aperture, said second segment also being located below said domed valve means and being wider than said cavity, said second raised segment cooperating with said valve means to selectively prevent the flow of fluids between said second aperture and said outlet passageway.

8. A disposable cassette as defined in claim 1, additionally comprising:

means for selectively preventing the flow of fluid through said cassette prior to installation of said cassette on said main unit, said preventing means being operable to allow the flow of fluid into said cassette prior to installation of said cassette on said main unit to prime said cassette.

9. A disposable cassette as defined in claim 8, wherein said preventing means comprises:

an outlet tube for receiving fluid pumped from said cassette body;

outlet tube mounting means located below said upper surface of said cassette body for attaching said outlet tube to said cassette body, the interior of said outlet tube communicating at one end thereof with said third aperture, said outlet tube being fixedly attached to said outlet tube mounting means and in fluid communication with the interior of said outlet tube; and

means for selectively clamping said outlet tube to prevent fluid from flowing through said cassette.

10. A disposable cassette as defined in claim 9, wherein said clamping means comprises:

a slide latch having a tear-shaped aperture therein, said tear-shaped aperture having a wider end and a narrower end;

means for supporting said slide latch, said supporting means being located below said upper surface of said cassette body, said slide latch being supported for slideable movement with said tear-shaped aperture being located under said outlet tube mounting means, said outlet tube extending through said tear-shaped aperture, said slide latch having a first position in which said outlet tube extends through said wider end of said tear-shaped aperture to allow fluid to flow through said outlet tube, said slide latch also having a second position in which said outlet tube extends through said narrower end of said tear-shaped aperture to prevent fluid from flowing through said outlet tube.

11. A disposable cassette as defined in claim 10, wherein said tear-shaped aperture is so arranged and configured to prevent the inadvertent flow of fluid prior to installation of said disposable cassette onto said medication infusion system.

12. A disposable cassette as defined in claim 1, wherein said domed valve means is made integrally with said diaphragm means, said diaphragm means being located around said domed valve means.

13. A disposable cassette as defined in claim 12, wherein said domed valve means and said diaphragm means are made of a medical grade silicone rubber.

14. A disposable cassette as defined in claim 1, additionally comprising:

a retainer cap for installation over said upper surface of said diaphragm means and said cassette body, said retainer cap for retaining said diaphragm means in a sealing relationship over said upper surface of said cassette body.

15. A disposable cassette as defined in claim 14, wherein said retainer cap has an aperture therein for allowing said domed valve means to project therethrough, said aperture in said retainer cap permitting access to said domed valve means to operate said domed valve means.

16. A disposable cassette as defined in claim 1, wherein said inlet and outlet passageways are essentially U-shaped.

17. A disposable cassette for use with a medication infusion system, comprising:

a cassette body having an upper surface, said cassette body including a cylinder disposed below the upper surface of said cassette, one end of said cylinder being sealingly attached to the bottom of said upper surface, the other end of said cylinder being open, said cassette body also including a bubble chamber disposed below the upper surface of said cassette body, said bubble chamber being open on the bottom side thereof, a siphon tube extending from the bottom of said upper surface nearly to the bottom of said bubble chamber, said cassette body also including an outlet tube disposed below the upper surface of said cassette, said upper surface of said cassette body having disposed therein first, second, and third apertures extending therethrough, said first aperture extending through said siphon tube, said second aperture being in communication with the interior of said cylinder at said one end thereof, said third aperture extending through said outlet tube;

a bubble chamber cap for sealing the open bottom of said bubble chamber, said bubble chamber cap including an inlet tube extending up into said bubble chamber from the bottom thereof above the bottom of said siphon tube;

piston means located in said cylinder for varying the fluid volume contained in said cylinder by alternately drawing fluid into said cylinder through said second aperture and forcing fluid out of said cylinder through said second aperture;

an inlet passageway recessed into said upper surface of said cassette body, said inlet passageway being open on the top side of said upper surface, one end of said inlet passageway being in fluid communication with said bubble chamber through said first aperture through which fluid is supplied to said inlet passageway, the other end of said inlet passageway being located near to said second aperture;

an outlet passageway recessed into said upper surface of said cassette body, said outlet passageway being open on the top side of said upper surface, one end of said outlet passageway being located near to said second aperture, the other end of said

outlet passageway being in fluid communication with said outlet tube through third aperture through which fluid is removed from said outlet passageway;

diaphragm means for sealing the open top sides of said inlet and outlet passageways and

flexible, resilient domed valve means for forming a cavity over a portion of said upper surface of said cassette body including said other end of said inlet passageway, said second aperture, and said one end of said outlet passageway, said cavity being in fluid communication with said inlet passageway, said second aperture leading to said cylinder, and said outlet passageway, said valve means being selectively deformable to prevent the flow of fluids between said inlet passageway and said second aperture, said valve means also being selectively deformable to prevent the flow of fluids between said second aperture and said outlet passageway.

18. A disposable cassette for use with a medication infusion system, comprising:

a cassette body having an upper surface which has disposed therein first, second, and third apertures extending therethrough, said upper surface of said cassette body having an inlet passageway recessed therein which inlet passageway extends between said first aperture and a location near to said second aperture, said upper surface of said cassette body also having an outlet passageway recessed therein which outlet passageway extends between said a location near to second aperture and said third aperture, said inlet and outlet passageways being open on the top side of said upper surface;

a cylinder disposed below the upper surface of said cassette, one end of said cylinder being sealingly attached to the bottom of said upper surface, the other end of said cylinder being open, said second aperture being in communication with the interior of said cylinder at said one end thereof;

piston means located in said cylinder for varying the fluid volume contained in said cylinder by alternately drawing fluid into said cylinder through said second aperture and forcing fluid out of said cylinder through said second aperture;

diaphragm valve means for sealing the open top sides of said inlet and outlet passageways, a portion of said diaphragm means forming a cavity over a portion of said upper surface of said cassette body including said other end of said inlet passageway, said second aperture, and said one end of said outlet passageway, said cavity being in fluid communication with said inlet passageway, said second aperture leading to said cylinder, and said outlet passageway, said portion of said diaphragm valve means being selectively deformable to prevent the flow of fluids between said inlet passageway and said second aperture, said portion of said diaphragm valve means also being selectively deformable to prevent the flow of fluids between said second aperture and said outlet passageway.

19. A method of making a disposable cassette for use with a medication infusion system, comprising:

locating a cylinder below the upper surface of a cassette body, one end of said cylinder being sealingly attached to the bottom of said upper surface, the other end of said cylinder being open, said upper surface of said cassette body having disposed therein first, second, and third apertures extending therethrough, said second aperture being in communication with the interior of said cylinder at said one end thereof;

installing piston means in said cylinder to allow the fluid volume contained in said cylinder to be varied by alternately drawing fluid into said cylinder through said second aperture and forcing fluid out of said cylinder through said second aperture;

providing an inlet passageway recessed into said upper surface of said cassette body, said inlet passageway being open on the top side of said upper surface, one end of said inlet passageway being in fluid communication with said first aperture through which fluid is supplied to said inlet passageway, the other end of said inlet passageway being located near to said second aperture;

providing an outlet passageway recessed into said upper surface of said cassette body, said outlet passageway being open on the top side of said upper surface, one end of said outlet passageway being located near to said second aperture, the other end of said outlet passageway being in fluid communication with said third aperture through which fluid is removed from said outlet passageway;

sealing the open top sides of said inlet and outlet passageways with diaphragm means; and

forming a cavity over a portion of said upper surface of said cassette body including said other end of said inlet passageway, said second aperture, and said one end of said outlet passageway with flexible, resilient domed valve means, said cavity being in fluid communication with said inlet passageway, said second aperture leading to said cylinder, and said outlet passageway, said valve means being selectively deformable to prevent the flow of fluids between said inlet passageway and said second aperture, said valve means also being selectively deformable to prevent the flow of fluids between said second aperture and said outlet passageway.