Intraocular lens with ultraviolet screening agent

• US 4,872,877 A
• Filed: 03/17/1987
• Issued: 10/10/1989
• Est. Priority Date: 03/17/1987
• Status: Expired due to Fees

• Current Assignee: Dennis T. Grendahl
• Original Assignee: Dennis T. Grendahl
• Inventors: Tiffany, John
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): PREBILIC, PAUL B
• Application Number:
  US07/026,631
• Time in Patent Office: 938 Days
• Field of Search: 8/467, 8/507, 8/648, 8/638, 250/519.1, 351/160 R, 351/160 H, 351/163, 351/166, 523/106, 523/107, 623/4, 623/5, 623/6, 623/901
• US Class Current: 623/6.56
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2/1616 Pseudo-accommodative, e.g. multifocal or enabling monovision
• CPC Class Codes: A61F 2002/16965 Lens includes ultraviolet absorber
• CPC Class Codes: A61L 2430/16 for reconstruction of eye parts, e.g. intraocular lens, cornea
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/50 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: C08G 18/837 by silicon containing compounds
• CPC Class Codes: C08J 7/065 Low-molecular-weight organic substances, e.g. absorption of additives in the surface of the article
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: G02B 1/043 Contact lenses
• CPC Class Codes: Y10S 623/901 Method of manufacturing prosthetic device

Abstract

An ultraviolet screening agent can be incorporated into a preformed silicone rubber intraocular lens by bringing it into contact with a solution which contains the agent in a higher concentration than the lens material.

Claims

1. A method for incorporating an ultraviolet screening agent into a preformed flexible silicone rubber intraocular lens, the method comprising:

a. preparing a solution of an ultraviolet screening agent in an organic liquid, the concentration of agent in the solution being such that the solution has a higher concentration of agent than the lens material;

b. bringing the lens and the solution into contact with each other until the lens and solution reach osmotic equilibrium;

c. separating the lens and the solution; and

,

d. drying the lens.

2. The method of claim 1 wherein the screening agent used is an o-hydroxyphenyl ketone, a hydroxybenzotriazole, or a phenylformamidine.

3. The method of claim 2 wherein the screening agent is 2,2'"'"'-dihydroxy-4,4'"'"'-dimethoxybenzophenone.

4. The method of claim 2 wherein the screening agent is 2-(2-hydroxy-4-methylphenyl)-benzo triazole.

5. The method of claim 2 wherein the screening agent is a phenylformamidine.

6. The method of claim 1 wherein the screening agent used is 2(3'"'"',5'"'"'-di-tert-butyl-2'"'"'-hydroxyphenyl)-5-chlorobenzotriazole.