Sliding test device for assays
First Claim
1. In a test device useful for conducting a reaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one reagent, to provide said reaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted reagent but not complexed or reacted reagent, and (c) an absorbent material underneath said filter effective to draw off liquid in said well after said reaction,the improvement wherein said device further includes (d) a non-absorbent pad underneath said filter, adjacent to said absorbent material, and (e) means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, one in which said filter contacts said non-absorbent pad and the other in which filter contacts said absorbent material.
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Accused Products
Abstract
An improved test device, useful in conducting reactions, which comprises (a) a well lconfigured to confine temporarily a liquid patient sample admixed with at least one reagent, such as an immunoreagent, to conduct such a reaction, (b) a filter at the bottom of the well with pores effective to pass free, unreacted reagent but not reacted or complexed reagent, and (c) an absorbent material underneath the filter effective to draw off liquid in the well after the reaction. The device further includes (d) a non-absorbent pad underneath the filter, adjacent to the absorbent material, and (e) means for moving the filter and the absorbent material relative to each other, and the filter and the pad relative to each other, between two positions, one in which the filter contacts the non-absorbent pad and the other in which the filter contacts the absorbent material.
76 Citations
13 Claims
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1. In a test device useful for conducting a reaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one reagent, to provide said reaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted reagent but not complexed or reacted reagent, and (c) an absorbent material underneath said filter effective to draw off liquid in said well after said reaction,
the improvement wherein said device further includes (d) a non-absorbent pad underneath said filter, adjacent to said absorbent material, and (e) means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, one in which said filter contacts said non-absorbent pad and the other in which filter contacts said absorbent material.
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10. In a test device for an immunoreaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one immunoreagent, to provide said immunoreaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted immunoreagent but not complexed immunoreagent, (c) an absorbent material underneath said filter effective to draw off liquid in said well after said immunoreaction, and (d) means for controlling liquid flow from said filter to said absorbent;
the improvement wherein said device further includes a non-absorbent pad underneath said filter, and wherein said liquid-controlling means comprise means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, to provide contact of said filter with either said non-absorbing pad or said absorbent material, so that proper alternating conditions of no flow or flow occur. - View Dependent Claims (11, 12, 13)
Specification