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Optical assay: method and apparatus

  • US 4,877,747 A
  • Filed: 04/04/1986
  • Issued: 10/31/1989
  • Est. Priority Date: 04/12/1985
  • Status: Expired due to Fees
First Claim
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1. An optical assay method comprising the following steps:

  • providing a coated metallic medium, the coating thereof being sensitized for a specific assay species;

    generating in the metallic medium a resonant signal at optical frequency, the power of this signal extending into the sensitized coating;

    providing coupling between said resonant signal and a monitored optical beam;

    exposing the coated metallic medium to a fluid assay sample; and

    ,measuring any changes in the optical beam to detect a response to the presence of the specific assay species in the fluid sample.

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