Dynamic coronary roadmapping

• US 4,878,115 A
• Filed: 09/25/1987
• Issued: 10/31/1989
• Est. Priority Date: 09/25/1987
• Status: Expired due to Fees

• Current Assignee: University Of Kentucky Research Foundation (University of Kentucky)
• Original Assignee: University Of Kentucky Research Foundation (University of Kentucky)
• Inventors: Elion, Jonathan L.
• Primary Examiner(s): Laroche, Eugene R.
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US07/101,074
• Time in Patent Office: 767 Days
• Field of Search: 358/111, 378/99, 378/98, 378/95, 128/654
• US Class Current: 378/98.5
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 6/503 for diagnosis of the heart
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: A61B 6/541 involving acquisition triggered by a physiological signal
• CPC Class Codes: H04N 5/3205 using subtraction imaging techniques

Abstract

A dynamic coronary roadmap of the coronary artery system is produced by recording and storing a visual image of the heart creating a mask sequence, recording and storing another dynamic visual image of the heart after injection of a contrast medium thereby creating a contrast sequence, matching the different durations of two sequences and subtracting the contrast sequence from the mask sequence producing a roadmap sequence. The roadmap sequence is then replayed and added to live fluoroscopic images of the beating heart. Replay of the roadmap sequence is triggered by receipt of an ECG R-wave. The result is a dynamically moving coronary roadmap image which moves in precise synchronization with the live incoming fluoroscopic image of the beating heart.

Claims

1. Method for producing a dynamic coronary artery system roadmap of a patient comprising the steps of:

recording and storing a dynamic visual image of a beating heart for a cardiac cycle so as to create a mask sequence;

injecting a visual contrast medium into the coronary artery system of the patient;

recording and storing a corresponding dynamic visual image of the beating heart for another cardiac cycle after injecting the contrast medium so as to create a contrast sequence; and

subtracting the corresponding contrast sequence from the mask sequence in order to produce the roadmap sequence of the coronary artery system.

2. The method of claim 1 wherein said subtracting step is performed in accordance with a gated subtraction process including the step of synchronizing the beginning of the mask and contrast sequences.

3. The method of claim 2 wherein the gated subtraction process includes a further step of frame by frame matching of the contrast and mask sequences.

4. The method of claim 3 wherein the gated subtraction process includes a further step of time stretching for matching the mask sequence to the contrast sequence where the mask and contrast sequences are of different duration.

5. The method of claim 4 wherein the time stretching is accomplished by adding filler frames to whichever sequence is shorter in duration, said filler frames being distributed evenly throughout the shorter duration sequence by replicating the preceding frame in the sequence.

6. The method of claim 4 wherein the time stretching is accomplished by adding filler frames to whichever sequence is shorter in duration, said filler frames being created by computing an average of the preceding and subsequent frame in the sequence between which a filler frame is to be positioned.

7. The method of claim 4 wherein the time stretching is accomplished by creating an entirely new sequence wherein each frame in the sequence of shorter duration contributes a fractional portion to one or more frames in the new sequence.

8. Method for producing a dynamic coronary artery system roadmap of a patient comprising the steps of:

recording and storing a dynamic visual image of a beating heart for a substantially full cardiac cycle so as to create a mask sequence;

injecting a visual contrast medium into the coronary artery system of the patient;

recording and storing another dynamic visual image of the beating heart for a substantially full cardiac cycle after injecting the contrast medium so as to create a contrast sequence; and

producing a substantially full contrast roadmap sequence.

9. The method of claim 8 wherein the producing step is performed in accordance with a binary discrimination process including the steps of computing the discrimination value for image brightness, and assigning all areas in the picture brighter than the determined value to white and all areas darker than the determined value to black thereby creating a substantially full contrast black and white image without shades of gray.

10. A method of displaying a representation of a dynamically beating coronary arterial system to assist in coronary angioplasty, comprising the steps of:

recording and storing dynamic visual images of a beating heart thereby creating a mask sequence of a complete cardiac cycle;

injecting a visual contrast medium into the patient;

recording and storing dynamic visual images of the beating heart after injecting the contrast medium thereby creating a contrast sequence of a complete cardiac cycle;

subtracting the contrast sequence from the mask sequence so as to create a preliminary roadmap sequence;

producing a substantially full contrast roadmap sequence from the preliminary roadmap sequence;

adding the full contrast roadmap sequence to a live dynamic visual image of the beating heart to produce an image of the roadmap overlaid on the image of the heart that moves in substantial synchronization with the beating heart thereby allowing an angiographer to accurately visualize the placement of a dilation balloon throughout the complete cardiac cycle.

11. The method of claim 10, wherein the method includes the step of triggering replay of the roadmap sequence in response to an incoming ECG R-wave signal so as to substantially synchronize the roadmap sequence with the actual beating of the heart at faster rates.

12. The method of claim 11 including the step of reusing a final frame of roadmap sequence frame until reception of the next incoming ECG R-wave so as to substantially synchronize the roadmap sequence with the actual beating of the heart at slower rates.

13. Apparatus for producing a dynamic coronary artery system roadmap of a patient including:

means for recording and storing a dynamic visual image of a beating heart for a cardiac cycle so as to create a mask sequence;

means for recording and storing a corresponding dynamic visual image of the beating heart for another cardiac cycle after injecting a contrast medium so as to create a contrast sequence;

means for matching sequences of different length by time stretching;

means for subtracting said corresponding contrast sequence from said mask sequence producing the roadmap sequence; and

means for producing a substantially full contrast sequence by binary discrimination.