Fibrillar product

• US 4,878,908 A
• Filed: 06/01/1988
• Issued: 11/07/1989
• Est. Priority Date: 08/05/1974
• Status: Expired due to Fees

• Current Assignee: Imperial Chemical Industries PLC (IMPERIAL CHEMICAL INDUSTRIES)
• Original Assignee: Imperial Chemical Industries PLC (IMPERIAL CHEMICAL INDUSTRIES)
• Inventors: Fildes, Francis J. T., Cockshott, Ian D., Martin, Graham E.
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US07/203,546
• Time in Patent Office: 524 Days
• Field of Search: 623/1, 128/156
• US Class Current: 623/1.54
• CPC Class Codes: A61L 15/24 Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof A61L15/225 takes precedence
• CPC Class Codes: A61L 15/425 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 2300/108 Elemental carbon, e.g. charcoal
• CPC Class Codes: A61L 2300/254 Enzymes, proenzymes
• CPC Class Codes: A61L 27/14 Macromolecular materials
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: B05B 5/0255 spraying and depositing by electrostatic forces only
• CPC Class Codes: B05B 5/043 using induction-charging
• CPC Class Codes: B32B 2262/0253 Polyolefin fibres vinyl or acrylic copolymers B32B2262/0223 or B32B2262/0246
• CPC Class Codes: B32B 2262/0292 Polyurethane fibres
• CPC Class Codes: B32B 2535/00 Medical equipment, e.g. bandage, prostheses, catheter medical patches B32B2556/00
• CPC Class Codes: B32B 3/04 characterised by at least one layer folded at the edge, e.g. over another layer ; characterised by at least one layer enveloping or enclosing a material
• CPC Class Codes: B32B 5/26 another layer next to it also being fibrous or filamentary relative arrangement of fibres or filaments of different layers B32B5/12
• CPC Class Codes: B32B 7/12 using interposed adhesives or interposed materials with bonding properties
• CPC Class Codes: C08L 27/18 Homopolymers or copolymers or tetrafluoroethene
• CPC Class Codes: C08L 75/00 Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
• CPC Class Codes: D01D 5/0007 Electro-spinning non-woven fabrics produced by electro-spinning D04H1/728
• CPC Class Codes: D04H 1/56 in association with fibre formation, e.g. immediately following extrusion of staple fibres
• CPC Class Codes: D04H 1/728 by electro-spinning electro-spinning methods and apparatus D01D5/0007
• CPC Class Codes: D04H 1/76 : otherwise than in a plane, e.g. in a tubular way
• CPC Class Codes: D04H 5/02 : strengthened or consolidated by mechanical methods, e.g. needling needling machines D04H18/00
• CPC Class Codes: Y10T 428/29 : Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof

Abstract

The disclosure relates to a prosthetic device and method for repairing a damaged blood vessel comprising a mat of fibers adjacent the bore of a tube having a disposition substantially parallel to the inner surface of the tube, the mat having a thickness of 0.5 mm to 5 mm.

Claims

1. A prosthetic device comprising a tube of vascular diameter said tube comprising an electrostatically spun mat of fibres of diameter 0.1 to 25 microns of a biologically acceptable polymeric material which is selected from the group consisting of polyurethane, polyamide or polyacrylonitrile, and fibres adjacent the bore of the tube having a disposition substantially parallel to the inner surface of the tube, said mat having a thickness of 0.5 mm to 5 mm.

2. A device according to claim 1 in which the fibres of the mat are of diameter 0.5 to 10 micron.

3. A device according to claim 1 in which the mat comprises non-woven fibres.

4. A device according to claim 1 in which the fibres of the mat are bonded one with another where they contact.

5. A device according to claim 1 the wall of which comprises a reinforcing component.

6. A device as in claim 5 wherein the thickness of the reinforcing component is less than the thickness of the mat.

7. A device according to claim 5 in which the reinforcement comprises a helical fibre.

8. A device as in claim 1 in which the tube is of internal diameter up to 3 centimeters.

9. A method of repairing a damaged blood vessel which comprises replacing at least a part of the damaged blood vessel with a prosthetic device comprising an electrostatically spun mat of fibres of diameter 0.1 to 25 microns of a biologically acceptable polymeric material which is selected from the group consisting of polyurethane, polyamide or polyacrylonitrile, and fibres adjacent the bore of the tube having a disposition substantially parallel to the inner surface of the tube, said mat having a thickness of 0.5 mm to 5 mm.