Antimicrobial surfaces and inhibition of microorganism growth thereby

• US 4,886,505 A
• Filed: 06/07/1985
• Issued: 12/12/1989
• Est. Priority Date: 06/07/1985
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Mansour, James D., Haynes, John L.
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US06/742,662
• Time in Patent Office: 1,649 Days
• Field of Search: 604/265, 604/280, 128/389, 128/391, 128/788
• US Class Current: 604/265
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61L 2300/102 Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/45 Mixtures of two or more drugs, e.g. synergistic mixtures
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

Apparatus having an antimicrobial surface includes a medical device and a plurality of metals, at least one of which is in contact with a surface of the device and in contact with a different metal. The invention includes a method to use the apparatus to treat a living body wherein the antimicrobial surface of the apparatus is contacted with a body electrolyte thereby inhibiting growth of microorganisms in the body consequent to the use of the apparatus.

Claims

1. An apparatus comprising a medical device, a switch and a plurality of metals, a first of said metals being a coating on a surface of said device and a second of said metals being in contact with a surface of said device, said first and second metals defining a space therebetween, said switch being affixed to one of said metals, said metals being connected to each other through said switch when said switch is closed but unconnected when said switch is open, whereby biological activity is imparted to a surface of the apparatus consequent to contact of said apparatus with an electrolyte of a living body when said switch is closed.