Cross-flow filtration
First Claim
1. A process for the cross-flow filtration of a liquid containing particulate or suspended solid and dissolved solids comprising circulating the liquid tangential to and axially on one side of a charge modified organic polymeric skinless microporous hollow fiber filter membrane, substantially retaining the particulate or suspended solids on said one side, the dissolved solids passing through the membrane and the charge on the membrane repelling similarly charged particulate or suspended particles preventing clogging or blocking of pores through excessive adsorption of said particulate or suspended solids.
4 Assignments
0 Petitions
Accused Products
Abstract
A process for the cross-flow filtration of a liquid comprising circulating the liquid tangential to a charge modified organic polymeric microporous filter membrane. Preferably, the membrane comprises an organic polymeric microporous filter membrane which has a micro-structure throughout the membrane and an amount of a charge modifying agent bound to substantially all of the membrance micro-structure without substantial pore size reduction or pore blockage.
The process may be used for the filtration of liquids, particularly parenteral or biological liquids contaminated with charged particulate and for plasmapheresis, particularly in the form of hollow fiber tubes.
121 Citations
33 Claims
- 1. A process for the cross-flow filtration of a liquid containing particulate or suspended solid and dissolved solids comprising circulating the liquid tangential to and axially on one side of a charge modified organic polymeric skinless microporous hollow fiber filter membrane, substantially retaining the particulate or suspended solids on said one side, the dissolved solids passing through the membrane and the charge on the membrane repelling similarly charged particulate or suspended particles preventing clogging or blocking of pores through excessive adsorption of said particulate or suspended solids.
Specification