Method and apparatus for ultrafast microwave tissue fixation
First Claim
Patent Images
1. An apparatus for fixating tissue comprising:
- means or holding said tissue submerged in a fixating solution;
a waveguide having a cavity formed therein with a first section, a second section, and a transition section formed therebetween, said waveguide having an opening at one end and a wall at the other end;
means for transmitting radio frequency energy through said opening and into said cavity;
an aperture disposed within said waveguide for inserting said tissue holding means within said second section, said aperture being positioned on said waveguide to cause a substantially uniform E field of said radio frequency energy through said tissue in said tissue holding means when inserted; and
an inductive post disposed within said second section adjacent said aperture, said post being positioned between said aperture and said wall.
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Abstract
A method and apparatus for ultrafast microwave tissue fixation using a single mode resonant waveguide constructed with an aperture near one end. The waveguide is also constructed to provide a uniform E field and maximum power field below the aperture. Tissue is placed into a vial filled with fixation solution. The vial and tissue are then inserted through the aperture into the waveguide. Microwave energy is then applied to the tissue which becomes fixated within a short period of time.
41 Citations
36 Claims
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1. An apparatus for fixating tissue comprising:
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means or holding said tissue submerged in a fixating solution; a waveguide having a cavity formed therein with a first section, a second section, and a transition section formed therebetween, said waveguide having an opening at one end and a wall at the other end; means for transmitting radio frequency energy through said opening and into said cavity; an aperture disposed within said waveguide for inserting said tissue holding means within said second section, said aperture being positioned on said waveguide to cause a substantially uniform E field of said radio frequency energy through said tissue in said tissue holding means when inserted; and an inductive post disposed within said second section adjacent said aperture, said post being positioned between said aperture and said wall. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 27)
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14. The method of fixating tissue in a waveguide having an aperture and a cavity with a first and second section formed therein, said cavity having a transitional section formed between said first and second section, said cavity having an opening at one end and a wall at the other end, comprising the steps of:
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placing the tissue to be fixated into a fixation solution in a vial; placing the vial into said aperture; providing radio frequency energy into said waveguide such that substantially uniform E field forms through said vial; and providing a conductive post within said cavity second section adjacent said aperture, said post being positioned between said aperture and said wall. - View Dependent Claims (15, 16, 17, 18, 19, 20, 22)
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21. An apparatus for fixating tissue comprising:
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a vial containing tissue submerged in a fixating solution; a single mode resonant waveguide having a cavity formed therein with a first section, a second section, and a transitional section formed therebetween, said waveguide having an opening at one end and a wall at the other end; means for transmitting radio frequency energy through said opening into said cavity; an aperture disposed within said waveguide for inserting said vial within said second section, said aperture being positioned on said waveguide a quarter wavelength of said radio frequency energy from said wall to cause a substantially uniform E field of said radio frequency energy through said vial when inserted; and an inductive post, disposed within said second section between said aperture and said wall and modifying impedance within said waveguide so that minimal microwave energy is reflected back to said transmitting means. - View Dependent Claims (23, 24, 25, 26)
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28. An apparatus for fixating tissue comprising:
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means for holding tissue submerged in a fixating solution, said tissue holding means having an outside surface; a waveguide having a cavity formed therein, said waveguide having an opening at one end and a wall at the other end; means for transmitting radio frequency energy through said opening and into said cavity; an aperture disposed within said waveguide for inserting said tissue holding means into said waveguide; and means for preventing moisture or any ionized gas from collecting on the outside surface of said tissue holding means. - View Dependent Claims (29, 30, 31)
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32. An apparatus for fixating tissue comprising:
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means for holding tissue submerged in a fixating solution; a waveguide having a cavity, said waveguide having an opening at one end and a wall at the other end; means for transmitting radio frequency energy through said opening and into said cavity; an aperture disposed within said waveguide for inserting said tissue holding means within said cavity, said aperture being positioned on said waveguide so that a substantially uniform E field of said radio frequency energy occurs in said tissue when said tissue holding means is inserted; and an inductive post, disposed within said cavity and adjacent said aperture. - View Dependent Claims (33)
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34. The method of fixating tissue in a microwave waveguide having a cavity comprising the steps of:
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placing the tissue to be fixated in a fixation solution in a vial; placing the vial into said cavity; providing radio frequency energy into said waveguide such that a substantially uniform E field forms through said vial; and providing a conductive post within said cavity adjacent said vial. - View Dependent Claims (35)
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36. The method of fixating tissue in a waveguide having a cavity formed therein comprising the steps of:
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holding tissue substantially submerged in a fixating solution within a vial; placing said vial in said waveguide cavity; transmitting said radio frequency energy in said waveguide; and preventing said tissue from touching the sides of said vial.
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Specification