Apparatus for treating blood in an extracorporeal circuit

• US 4,894,164 A
• Filed: 10/27/1987
• Issued: 01/16/1990
• Est. Priority Date: 10/30/1986
• Status: Expired due to Term

• Current Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Inventors: Polaschegg, Hans-Dietrich
• Primary Examiner(s): JONES, WILLIAM G
• Application Number:
  US07/114,346
• Time in Patent Office: 812 Days
• Field of Search: 604/4, 604/5, 422/46, 422/48, 210/644, 210/645, 210/646, 210/647, 210/649, 210/651, 210/652, 210/742, 210/805, 210/175, 210/177, 210/181, 210/195.1, 210/195.2, 210/321.65, 210/321.72 , 210/184, 210/186, 210/85, 210/97, 210/650, 210/149
• US Class Current: 210/646
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1664 with temperature control
• CPC Class Codes: A61M 1/3462 Circuits for the preparation thereof
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 2205/366 by liquid heat exchangers
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media

Abstract

An apparatus for treating blood in an extracorporeal circuit for hemodialysis of hemofiltration and a method for withdrawing heat from blood in an extracorporeal circuit wherein blood is brought into contact along a membrane with a treatment solution which has been heated to a temperature in a source making the treatment of fluid available such that the energy balance of the patient is maintained, the temperature of the source being controlled in that the temperature of the blood emerging from the patient is measured, the temperature value obtained is compared with a predetermined temperature value and on determination of a difference between the two values the source temperature is changed.

Claims

1. A method for withdrawing heat from blood in a extracorporeal circuit employing a treatment solution wherein blood is brought into contact with the treatment solution along a membrane and wherein the treatment solution has been heated in a source supplying the treatment solution, in order to maintain energy balance of a patient, the method comprising:

establishing a reference temperature value for the blood prior to starting treatment;

measuring the temperature of blood emerging from said patient'"'"'s body during use of the treatment solution to obtain a first measured temperature value correlated with the body temperature of the patient;

comparing the first measured temperature value with the reference value to obtain a comparison value; and

continuously adjusting the temperature of the treatment solution in response to the comparison value to maintain the comparison value in order to maintain an energy balance of the patient.

2. The method according to claim 1 further including the step of performing hemodialysis with a dialysis solution, wherein said treatment solution is said dialysis solution.

3. The method according to claim 1 further including the step of performing hemofiltration with a substitution solution, wherein said treatment solution is said substitution solution.

4. The method according to claim 1 wherein said temperature measuring step comprises measuring arterial blood temperature.

5. The method according to claim 1 wherein said temperature measuring step comprises measuring venous blood temperature.

6. The method according to claim 1 wherein said reference value establishing step comprises:

measuring arterial blood temperature prior to start of application of said treatment solution to the patient.

7. The method according to claim 6 further including the step of:

integrating with respect to time the currently withdrawn energy to obtain total withdrawn energy for said time.

8. The method according to claim 1 wherein said reference value establishing step comprises:

measuring the temperature difference between arterial blood temperature and venous blood temperature prior to start of application of said treatment solution to the patient to obtain a reference value representative of said reference temperature value.

9. The method according to claim 1 further including the steps of:

measuring the arterial blood temperature;

measuring the venous blood temperature;

forming a current difference between the arterial blood temperature and the venous blood temperature;

measuring volume of blood delivered in the extracorporeal circuit to obtain a withdrawn volume value; and

calculating currently withdrawn energy from the current difference and the withdrawn volume value.

10. An apparatus for treating blood in an extracorporeal circuit comprising:

a treatment element which is divided by a membrane into a first chamber and a second chamber,

a treatment solution source, said first chamber being connected in a solution path with said treatment solution source,

a temperature regulating unit, said treatment solution source being coupled to said temperature regulating unit,

said temperature regulating unit having a temperature detector disposed within said treatment solution source, a heating means for heating solution in said treatment solution source and a first control unit,

a conduit for conveying blood along a blood path,

a blood pump, said blood pump being coupled in said blood path with said second chamber,

a first temperature sensor disposed in said blood path upstream of said treatment element for measuring blood temperature emerging from the body of a patient, and

a second control unit, said second control unit being coupled to said first temperature sensor and to said first control unit, said second control unit comprising a means for comparing an actual value received from said first temperature sensor with a preselected desired value and upon deviation therefrom regulating the temperature of said solution by controlling said first control unit to heat and cool said solution.

11. The apparatus according to claim 10 wherein said treatment element is a hemodialyzer or hemodiafilter and wherein said treatment solution is a dialysis solution.

12. The apparatus according to claim 10 further including a second temperature sensor coupled in said blood path downstream of said treatment element and coupled to said second control unit for providing temperature readings of blood returning to the body of the patient.

13. The apparatus according to claim 10 further including a programmable input device and wherein said second control unit is coupled to receive input control signals from said programmable input device.

14. The apparatus according to claim 10 wherein said second control unit is coupled to receive a predetermined temperature value and to receive blood flow information and further comprises means for determining amounts of energy withdrawn from the blood in order to determine amounts of energy to be returned to the blood by regulating the temperature of said solution by controlling said first control unit to heat and cool said solution.

15. The apparatus according to claim 10 further including means coupled to a display unit to receive temperature values and pump rates for displaying temperature values, pumping rates energy values.

16. An apparatus for treating blood in an extracorporeal circuit comprising:

a treatment element which is divided by a membrane into a first chamber and a second chamber,

a hemofiltrate receptacle, said first chamber being connected in a solution path with said hemofiltrate receptacle,

a conduit for conveying blood along a blood path,

a blood pump, said blood pump being coupled in said blood path upstream of said second chamber,

a substitution fluid supply unit coupled to said blood path through a supply conduit, said substitution fluid supply unit comprising a second pump for pumping a substitution fluid, a first control unit and a temperature regulating unit,

a first temperature sensor disposed in said blood path upstream of said treatment element for measuring blood temperature emerging from the body of a patient, and

a second control unit, said second control unit being coupled to said first temperature sensor and to said first control unit, said second control unit comprising a means for comparing an actual value received from said first temperature sensor with a preselected desired value and upon deviation therefrom regulating the temperature of said solution by controlling said first control unit to heat and cool said solution.

17. The apparatus according to claim 16 further including a second temperature sensor coupled in said blood path downstream of said treatment element and coupled to said second control unit for providing temperature readings of blood returning to the body of the patient.

18. The apparatus according to claim 16 further including a programmable input device and wherein said second control unit is coupled to receive input control signals from said programmable input device.

19. The apparatus according to claim 16 wherein said second control unit is coupled to receive a predetermined temperature value and to receive blood flow information and further comprises means for determining amounts of energy withdrawn from the blood in order to determine amounts of energy to be returned to the blood by regulating the temperature of said solution by controlling said first control unit to heat and cool said solution.

20. The apparatus according to claim 16 further including means coupled to a display unit to receive temperature values and pump rates for displaying temperature values, pumping rates energy values.

21. Device for determining heat flow of a blood cleaning apparatus having an extracorporeal blood circuit, said blood circuit being connected through a treatment element which is either a hemofilter or a dialyzing element, said blood circuit having a blood pump capable of pumping blood at a selected pump rate, said device comprising:

a first temperature sensor disposed in said blood circuit upstream of said treatment element;

a second temperature sensor disposed in said blood circuit downstream of said treatment element; and

a control unit, said control unit being coupled to said first temperature sensor, to said second temperature sensor and to said blood pump, said control unit comprising means for receiving as input signals a first temperature value from said first temperature sensor, a second temperature value from said second temperature sensor and a pump rate value of said blood pump, said control unit further comprising means for determining continuously from differences between said first and second temperature values and from said pump rate value said heat flow, and said control unit additionally comprising means for providing as an ongoing output said heat flow.

22. Device for determining heat flow of a blood cleaning apparatus having an extracorporeal blood circuit, said blood circuit being connected through a treatment element which is either a hemofilter or a dialyzing element, said blood circuit having a blood pump capable of pumping blood at a selected pump rate, said device comprising:

a temperature sensor disposed in said blood circuit upstream of said treatment element; and

a control unit, said control unit being coupled to said temperature sensor and to said blood pump, said control unit comprising means for receiving as input signals a first temperature value from said temperature sensor at the beginning of a treatment, a substantially continuous second temperature value from said temperature sensor during treatment and a pump rate value of said blood pump, said control unit further comprising means for determining continuously from differences between said first and second temperature values and from said pump rate value said heat flow, and said control unit additionally comprising means for providing as an ongoing output said heat flow.