Peroxide gel dentifrice compositions

• US 4,895,721 A
• Filed: 01/22/1988
• Issued: 01/23/1990
• Est. Priority Date: 01/22/1988
• Status: Expired due to Term

• Current Assignee: Church & Dwight Company Incorporated
• Original Assignee: Carter-Wallace Incorporated
• Inventors: Drucker, Jacob
• Primary Examiner(s): Rose, Shep K.
• Application Number:
  US07/146,902
• Time in Patent Office: 732 Days
• Field of Search: 424/53, 424/130, 424/616
• US Class Current: 424/53
• CPC Class Codes: A61K 2800/522 Antioxidants; Radical scavengers
• CPC Class Codes: A61K 8/042 Gels
• CPC Class Codes: A61K 8/22 Peroxides; Oxygen; Ozone
• CPC Class Codes: A61K 8/345 containing more than one hydroxy group
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

Stable aqueous peroxide dentifrice gel compositions which are stable against both viscosity and peroxide loss and which contain up to about 15% by weight of aqueous peroxide, and from about 35% to about 95% by weight of a polyol or a mixture of polyols, from about 0.75% to about 5.0% by weight of a gelling agent and from about 0.05% to about 1.0% by weight of stabilizers are disclosed.

Claims

1. Stable, aqueous, non-relaxing peroxide gel compositions consisting essentially of from about 35% to about 95% by weight of a complexing agent selected from the group consisting of ethylene polymers of the formula HOCH₂ (CH₂ OCH₂)_n CHOH wherein n has a value of 3to 1000 and mixtures thereof, from about 0.75% to about 5.00% by weight of a gelling agent selected from the group consisting of carboxypolymethylene polymers comprising a major portion of an alpha, beta-olefinically unsaturated carboxylic acid and a minor portion of a polyalkenyl polyether or a polyol and carboxy vinyl polymers, from about 0.05% to about 1.00% by weight of a peroxide stabilizer selected from the group comprising butylated hydroxyanisole, butylated hydroxy toluene, propyl gallate, sodium 2,2'"'"'-dihydroxy-4,4'"'"'-dimethoxy-5-sulphobenzone, lauryl dibutylamine oxide and the like and up to about 15.00% by weight of hydrogen peroxide.

2. Aqueous peroxide gels as claimed in claim 1 wherein said complexing agents have molecular weights of from about 200 to about 7500.

3. Aqueous peroxide gels as claimed in claim 2 wherein said complexing agents are selected from the group comprising glycerol, sorbitol, mannitol, propylene glycol and polyalkylene glycols.

4. Aqeous peroxide gels as claimed in claim 1 wherein said gelling agent is a copolymer of acrylic acid cross-linked with from about 0.75% to about 1.5% by weight, based on the weight of acrylic, of polyallyl sucrose.

5. A dentifrice composition consisting essentially of about 1.50% by weight of a copolymer of acrylic acid and polyallylosucrose having an average of about 8.8 allyl groups per sucrose molecule, about 30.00% by weight of a polyethylene glycol polymer having an average of about 400 oxyethylene groups, about 25.00% by weight glycerine, about 0.50% by weight butylated hydroxy anisole, about 10.00% by weight hydrogen peroxide in a 35.00% by weight aqueous hydrogen peroxide solution, about 0.50% by weight sodium saccharin, about29.00% by weight calcium pyrophosphate, about 1.50% by weight sodium lauryl sarcosinate, about 1.50% by weight tetrasodium pyrophosphate and about 1.00% by weight flavor.