Sliding reconstitution device with seal

• US 4,898,209 A
• Filed: 09/27/1988
• Issued: 02/06/1990
• Est. Priority Date: 09/27/1988
• Status: Expired due to Term

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Zbed, Brian D.
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US07/249,747
• Time in Patent Office: 497 Days
• Field of Search: 604/413, 604/411, 604/410, 604/414, 604/416, 604/88, 137/614.04, 206/221, 220/265
• US Class Current: 137/614.04
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1475 Inlet or outlet ports
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2013 having two piercing ends
• CPC Class Codes: A61J 1/2051 having tap means, e.g. tap means activated by sliding
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 2200/10 Coring prevention means, e.g. for plug or septum piecing members
• CPC Class Codes: Y10T 137/87957 Valves actuate each other

Abstract

A coupling device for establishing fluid communication between a first container and a second container is provided. The device includes a first sleeve member including at a first end thereof, a member for connecting and securing the first sleeve member to a first container. A second sleeve member is provided and is so constructed and arranged that it receives a portion of the first sleeve, and is operatively adapted for axial sliding engagement thereon, including at one axial end thereof a member for releasably engaging and securing the second sleeve member to a second container. Piercing members located within an area defined by the first and second sleeves are provided for providing fluid flow from the first container to the second container. The coupling device includes a resilient seal for sealing an end of the second sleeve member, located in said second sleeve member at said end adapted to be connected to said second container.

Claims

1. A coupling device for establishing fluid communication between a first container and a second container comprising:

a first sleeve member including at a first end thereof, means for connecting and securing said first sleeve member to a first container;

a second sleeve member, so constructed and arranged that it receives a portion of the first sleeve, and operatively adapted for axial sliding engagement thereon, including means at one axial end thereof for releasably engaging and securing said second sleeve member to a second container;

piercing means located within the first and second sleeves and secured to one of the sleeves for providing fluid flow from the first container to the second container; and

a resilient seal means for sealing an end of the second sleeve member, located in said second sleeve member at said end adapted to be connected to said second container.

2. The coupling device of claim 1 wherein the seal means includes a gasket that creates a seal between a first area located on one side of the gasket and a second area located on a second side of the gasket.

3. The coupling device of claim 1 wherein the seal member includes a resilient sleeve member extending axially from a portion of the seal member.

4. The coupling device of claim 1 including means for releasably securing the first and second sleeves in a first or second axial position.

5. The coupling device of claim 4 wherein said means for releasably securing said first and second sleeve members includes a bayonet socket arrangement.

6. The coupling device of claim 1 including means for releasably securing the first and second sleeves in a first or second rotational position.

7. The coupling device of claim 1 wherein said means for connecting said first sleeve member to said container includes means for allowing a portion of the container to be received within said first sleeve member but preventing the portion from being released therefrom.

8. The coupling device of claim 1 wherein said seal member is formed of a molded rubber and said first and second sleeve members are made of plastic.

9. The coupling device of claim 1 wherein said piercing means includes two piercing members, one of which is so constructed and arranged that it can pierce the first container and a second of which that is so constructed and arranged that it can pierce the second container.

10. The coupling device of claim 9 wherein said first and second piercing members are made of plastic and are integrally formed with said first sleeve member.

11. The coupling device of claim 9 wherein the first sleeve includes at a second axial end an end wall and the piercing members extend outwardly from opposite sides of the end wall.

12. The coupling device of claim 1 wherein the seal means prevents fluid contained in the second sleeve from leaking out of the coupling device.

13. The coupling device of claim 1 wherein the seal means prevents microbial ingress into the second sleeve member via the second end.

14. A coupling device for establishing fluid communication between a first container and a second container comprising:

a first sleeve member having a first end adapted to securely receive a portion of the first container;

a pair of oppositely extending first and second hollow piercing members located within and secured to the first sleeve, the piercing members including channels in fluid communication with each other, the first piercing member adapted to pierce the first container and the second piercing member adapted to pierce the second container;

a second sleeve member concentrically engaged about said first sleeve member and operatively adapted to axial sliding engagement thereon, the second sleeve including an end for releasably securing the second container;

said first and second sleeves cooperating to define means for releasably securing said first and second sleeves in a first or second axial position relative to each other; and

a molded rubber seal member located within said second sleeve member in juxtaposition to the end of the second sleeve, said seal defining a seal between a first area within the second sleeve and a second area outside the sleeve.

15. The coupling device of claim 14 wherein the first piercing member includes a solid tip.

16. The coupling device of claim 14 wherein the second piercing member includes an oblique-shaped end.

17. The coupling device of claim 14 wherein the seal includes a gasket extending across a face of the end of the outer sleeve.

18. The coupling device of claim 17 wherein the gasket prevents microbial ingress into the first area and into the second container when the sleeve is secured to the second container.

19. The coupling device of claim 14 wherein the seal includes a sleeve, having a pierceable membrane at one end and an opening at a second end, the sleeve being so constructed and arranged that it receives a portion of the second piercing member.

20. The coupling device of claim 14 wherein said first piercing member extends for a length sufficient to cause the piercing member to pierce a portion of the first container when the first sleeve is secured to the container.

21. The coupling device of claim 14 wherein the means for releasably securing the first and second sleeves in a first or second position includes a flange circumscribing an outer portion of the first sleeve and a flange circumscribing an inner portion of the second sleeve and at least one rib located on the inner portion of the second sleeve.

22. The coupling device of claim 21 wherein flange on the first sleeve includes at least one gap for receiving the rib.

23. The coupling device of claim 21 wherein the flange on the second sleeve includes a gap therebetween for receiving the flange on the first sleeve.

24. The coupling device of claim 23 wherein the gap on the first sleeve includes means for limiting the rotational movement of the first sleeve with respect to the second sleeve.

25. The coupling device of claim 14 including means for releasably securing the first and second sleeves in a first or second rotational position with respect to each other.

26. A connector mixing two products comprising:

first and second sleeves operatively adapted for limited rotation and axial movement relative to each other, the second sleeve member concentrically located about the first sleeve member;

means formed at an axial end of the first sleeve for securing the first sleeve member to a container;

means formed at an axial end of the second sleeve for releasably connecting the second sleeve to a second container;

the first and second sleeves defining means for releasably securing the first and second sleeve members in a first axial position or a second axial position and securing the sleeves in a first rotational position or a second rotational position;

first and second piercing members located within and secured to the first sleeve, the first piercing member adapted to pierce the first container when the first sleeve member is connected to the container, the second piercing member adapted to pierce the second container when the container is secured to the second sleeve and the sleeves are in a second axial position; and

a molded rubber seal member located in the second sleeve member and having a disc-shaped gasket member adapted to cover and seal the outer sleeve.

27. The connector of claim 26 wherein the seal includes a resilient sleeve extending axially from a center portion of the gasket that operatively surrounds and seals the second piercing member.

28. The connector of claim 27 wherein the sleeve includes a pierceable membrane at an end thereof.

29. The coupling device of claim 26 wherein the means for releasably securing the first and second sleeves in a first or second position includes a flange circumscribing an outer portion of the first sleeve and a flange circumscribing an inner portion of the second sleeve and at least one rib located on the inner portion of the second sleeve.

30. The coupling device of claim 29 wherein the flange on the second sleeve includes a gap therebetween for receiving the flange on the first sleeve.

31. The coupling device of claim 30 wherein the gap on the first sleeve includes means for limiting the rotational movement of the first sleeve with respect to the second sleeve.

32. The coupling device of claim 26 wherein flange on the first sleeve includes at least one gap for receiving the rib.