Portable infusion device assembly

• US 4,898,582 A
• Filed: 08/09/1988
• Issued: 02/06/1990
• Est. Priority Date: 08/09/1988
• Status: Expired due to Fees

• Current Assignee: Pharmetrix Corporation
• Original Assignee: Pharmetrix Corporation
• Inventors: Faste, Rolf A.
• Primary Examiner(s): Pellegrino, Stephen C.
• Application Number:
  US07/230,620
• Time in Patent Office: 546 Days
• Field of Search: 604/891.1, 604/892.1, 604/896, 604/131, 604/141, 604/151, 604/93, 604/244, 128/DIG. 12
• US Class Current: 604/141
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/145 using pressurised reservoirs, e.g. pressurised by means of pistons
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

A portable infusion device assembly, having two side-by-side compartments, the first containing the drug or agent to be infused and an osmotic pump, and the second containing the driving liquid for the pump. The two chambers are separated during storage by a barrier. When the barrier is ruptured, the driving fluid is carried by means of a wick to the osmotic pump. The drug is then forced out of the device by the pressure developed by the osmotic pump. The assembly is characterized by a very flat profile, and is light, comfortable, and inconspicuous in use.

Claims

1. A portable infusion device assembly, comprising;

(a) a housing, defining first and second compartments disposed in side-by side relationship to one another,

(b) an osmotic pump, disposed within said first compartment,

(c) a driving liquid for said pump disposed within said second compartment,

(d) wick means, disposed within said housing, in liquid transferring relationship between said first and second compartments,

(e) a barrier disposed between said wick means and said driving liquid, and separating said driving liquid from said wick, and

(f) means integral with said housing or said barrier for rupturing said barrier so that upon rupture of said barrier, said driving liquid will be transferred by said wick from said second compartment to said first compartment.

2. A portable infusion device, comprising;

(a) a flexible housing, defining first and second compartments disposed in side-by side relationship to one another,

(b) an osmotic pump, disposed within said first compartment,

(c) a driving liquid for said pump disposed within said second compartment,

(d) wick means, disposed within said housing, in liquid transferring relationship between said first and second compartments,

(e) a barrier disposed between said wick means and said driving liquid, and separating said driving liquid from said wick, and

(f) means integral with said housing or said barrier for rupturing said barrier so that upon rupture of said barrier, said driving liquid will be transferred by said wick from said second compartment to said first compartment.

3. A housing for a portable osmotic device, comprising;

(a) a baseplate,

(b) an upper portion designed in such a manner that side-by-side compartments are created when said upper portion is sealed to said baseplate around its perimeter,

(c) a support means within said first compartment for holding an osmotic pump,

(d) a wick means, disposed within said housing, in liquid transferring relationship between said first and second compartments and

(e) sealing means for isolation said first compartment from said second compartment.

4. The housing of claim 3, wherein said baseplate is flexible.

5. The housing of claim 3, where said upper portion is of flexible construction.

6. The housing of claim 3, wherein said compartment surfaces are of flexible construction.

7. The housing of claim 3, wherein said support means and said sealing means comprise a single internal support member disposed generally parallel to said baseplate, said single internal support being sealed to said raised portion around its perimeter and between said first and second compartments.

8. A method of infusing a patient, comprising connecting said patient to a portable osmotic infusion device, said device comprising:

(a) a housing, defining first and second compartments disposed in side-by-side relationship to one another,

(b) an osmotic pump, disposed within said first compartment,

(c) a driving liquid for said pump disposed within said second compartment,

(d) wick means, disposed within said housing, in liquid transferring relationship between said first and second compartments,

(e) a barrier disposed between said wick means and said driving liquid, and separating said driving liquid from said wick,

(f) means integral with said housing or said barrier for rupturing said barrier so that upon rupture of said barrier, said driving liquid will be transferred by said wick from said second compartment to said first compartment,

(g) activating said device by rupturing said barrier.