Cerebral biopotential analysis system and method
First Claim
1. A method of noninvasively detecting cerebral irregularities that effect cerebral electrical activity, said method comprising the steps of:
- acquiring electroencephalographic signals from a surface of a region of the head of a subject being analyzed through a surface electrode;
dividing said acquired signals into segments and representing said segments as data records;
computing bispectral values for all data records of said acquired signals;
utilizing said bispectral values to generate single number indices to quantify a contribution to overall cerebral electrophysiologic stability provided by the region to which said surface electrode is connected.
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Abstract
Disclosed is a biopotential analysis system and method of the present invention for determining, in a noninvasive manner, cerebral electrical properties. A suitable electrode and amplifier system is used to obtain biopotentials from the region of interest. Surface electroencephalographic signals are then digitized and transmitted over a serial RS232C line to a host computer where a two minute long signal is divided into 30 consecutive four second intervals. A fast Fourier transform (FFT) is then performed on every interval, and the resulting fast Fourier transforms are then used to produce bispectral complex triple product and bispectral real triple product arrays for that interval. The complex triple product arrays of all intervals are added together, and the real triple product arrays of all intervals are also added together. Each element in the final complex array and final real array is then divided by 30 (the number of intervals) to produce an average complex triple product array and an average real triple product array. The magnitude squared of each element in the complex triple product array is divided by the corresponding element in the real triple product array to form the bicoherence array. The bicoherence array is displayed on a video terminal or plotted, and is used as a figure of merit for the assessment of cerebral electrical function.
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Citations
28 Claims
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1. A method of noninvasively detecting cerebral irregularities that effect cerebral electrical activity, said method comprising the steps of:
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acquiring electroencephalographic signals from a surface of a region of the head of a subject being analyzed through a surface electrode; dividing said acquired signals into segments and representing said segments as data records; computing bispectral values for all data records of said acquired signals; utilizing said bispectral values to generate single number indices to quantify a contribution to overall cerebral electrophysiologic stability provided by the region to which said surface electrode is connected. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A system for noninvasively detecting cerebral irregularities that affect cerebral electrical acitvity, said system comprising:
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means for acquiring electroencephalographic signals from a surface of the head of a subject being analyzed; means for dividing said acquired electroencephalographic signals into a plurality of data records; means for computing at least one array of bispectral values from said data records of electroencephalographic signals; means for utilizing said at least one array of bispectral values to generate single number indices to quantify a contribution to overall cerebral electrophysiologic stability provided by a region to which said means for acquiring electroencephalographic signals is connected. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28)
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Specification