Optical fiber distribution system for an optical fiber sensor

• US 4,907,857 A
• Filed: 06/14/1989
• Issued: 03/13/1990
• Est. Priority Date: 07/25/1988
• Status: Expired due to Fees

• Current Assignee: Abbott Laboratories Incorporated
• Original Assignee: Abbott Laboratories Incorporated
• Inventors: Giuliani, David, Gutcheck, Robert A.
• Primary Examiner(s): Sikes, William L.
• Assistant Examiner(s): Ullah, Akm E.
• Application Number:
  US07/366,762
• Time in Patent Office: 272 Days
• Field of Search: 350/96.10, 350/96.29, 250/227, 250/231 R, 356/40, 356/41, 356/320
• US Class Current: 385/12
• CPC Class Codes: G01N 2021/7786 Fluorescence
• CPC Class Codes: G01N 21/6408 with measurement of decay time, time resolved fluorescence
• CPC Class Codes: G01N 21/6428 Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" in vivo A61B5/00; immunoassay G01N33/53
• CPC Class Codes: G01N 21/7703 using reagent-clad optical fibres or optical waveguides using measurement of total internal reflection or attenuated total reflection G01N21/552; optical fibres or waveguides per se G02B
• CPC Class Codes: G01N 21/783 for analysing gases
• CPC Class Codes: G01N 21/80 Indicating pH value
• CPC Class Codes: G02B 6/28 having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
• CPC Class Codes: G02B 6/2808 using a mixing element which evenly distributes an input signal over a number of outputs

Abstract

A device for distributing signals within a sensor system used for monitoring the presence of a specific analyte in a composition by means of an analyte-sensitive indicator molecule is disclosed. The sensor system includes a signal-generating component, a single-fiber sensor tip that houses the indicator molecule and a signal-measuring component. In one embodiment, the signal-generating component generates a first optical signal of a wavelength that is sensitive to the indicator molecule, and a second optical signal of a wavelength that is predictably altered by the indicator molecule. The distribution system includes lengths of optical fiber, a dividing connector, a mixing connector, a transmitting connector and a tip connector. The dividing connector connects at least three intermediate fibers to the signal-generating component to receive intermediate signals. The mixing connector connects a mixing fiber to the intermediate fibers to receive the intermediate signals and blend them into a single mixed signal. The transmitting connector connects a transmitting fiber to the mixing fiber to thereby receive a portion of the mixed signal, and connects a comparison fiber to the mixing fiber to transmit a portion of the mixed signal to the signal-measuring component. The tip connector connects the transmitting fiber to the sensor tip fiber to transmit a portion of the mixed signal to the sensor tip, and connects an indicator fiber to the sensor tip to transmit a portion of the resulting indicator signal returned from the sensor tip to the signal-measuring component.

Claims

1. A distribution system for a sensor that utilizes an analyte-sensitive indicator molecule to monitor the concentration of an analyte, the sensor having:

a signal-generating component for producing first and second optical signals of distinct wavelengths, the first signal wavelength being such that the signal intensity is altered by the indicator molecule in proportion to the presence of the analyte, the second signal wavelength being such that the intensity of the signal is predictably altered by the indicator molecule so that the intensity of the returned signal is predictable;

a single-fiber sensor tip that includes the indicator molecule; and

a signal-measuring component for receiving signals from the distribution system, the distribution system comprising;

lengths of optical fiber of first and second diameters, said second diameter being larger than said first diameter;

a dividing connector for connecting at least three intermediate fibers of said first diameter to the signal-generating component to thereby receive intermediate signals, at least one intermediate signal corresponding to the wavelength of the first signal and one intermediate signal corresponding to the wavelength of the second signal;

a mixing connector for connecting a mixing fiber of said second diameter to said intermediate fibers to thereby receive said intermediate signals and blend them into a single mixed signal, said mixing fiber being of a suitable length to mix the first and second signals into a single mixed signal distributed uniformly across said mixing fiber;

a transmitting connector for connecting a transmitting fiber of said first diameter to said mixing fiber to thereby receive a portion of said mixed signal; and

a tip connector for connecting said transmitting fiber to the sensor tip fiber to thereby transmit said mixed signal to the sensor tip, and for connecting an indicator fiber of said first diameter to the sensor tip to thereby transmit a portion of the resulting indicator signal returned from the sensor tip to the signal-measuring component, whereby the intensity of said intermediate signals corresponding to the first signal is maximized at the dividing connector, the intensity of said intermediate signals corresponding to the first signal being bounded by the transmission of intermediate signals corresponding to the second signal of adequate intensity such that the intensity of the indicator signal of a wavelength corresponding to the wavelength of the second signal received by the signal-measuring component is suitable for monitoring the operation of the distribution system.

2. The distribution system as claimed in claim 1, wherein said dividing connector, said mixing connector, said transmitting connector, and said tip connector each includes a butt-coupler pair.

3. The distribution system as claimed in claim 1, wherein said dividing connector connects three intermediate fibers to the signal-generating component to thereby receive signals of the first signal wavelength and connects one intermediate fiber to the signal-generating component to thereby receive signals of the second signal wavelength.

4. The distribution system as claimed in claim 3, wherein said transmitting connector connects a plurality of said transmitting fibers to said mixing fiber, and wherein said tip connector connects a plurality of indicator fibers to the sensor tip.

5. The distribution system as claimed in claim 1, wherein the relationship of said first diameter relative to said second diameter, and the configurations of said dividing connector, said mixing connector, said transmitting connector, and said tip connector, are such that at each connector where a fiber of said first diameter is connected to a fiber of said second diameter, the fiber of said second diameter completely subtends the fiber of said first diameter.

6. The optical fiber distribution system as claimed in claim 1, wherein said optical fibers are encased in polyvinyl chloride casing.

7. The optical fiber distribution system as claimed in claim 1, wherein said transmitting connector connects a comparison fiber of said first diameter to said mixing fiber to thereby transmit a portion of said mixed signal to the signal-measuring component.

8. The distribution system as claimed in claim 7, wherein said dividing connector, said mixing connector, said transmitting connector, and said tip connector each includes a butt-coupler pair.

9. The distribution system as claimed in claim 7, wherein said dividing connector connects three intermediate fibers to the signal-generating component to thereby receive signals of the first signal wavelength and connects one intermediate fiber to the signal-generating component to thereby receive signals of the second signal wavelength.

10. The distribution system as claimed in claim 7, wherein the relationship of said first diameter to said second diameter, and the configurations of said dividing connector, said mixing connector, said transmitting connector, and said tip connector, are such that at each connector where a fiber of said first diameter is connected to a fiber of said second diameter, the fiber of said second diameter completely subtends the fiber of said first diameter.

11. The optical fiber distribution system as claimed in claim 7, wherein said optical fibers are encased in polyvinyl chloride casing.

12. The distribution system as claimed in claim 1, wherein the diameter of said mixing fiber is substantially equal to the diameter of the sensor tip fiber.

13. A distribution system for an environmental parameter measuring sensor, the sensor having:

a single-fiber sensor tip that includes means for altering a light signal in accordance with the presence of the environmental parameter to be measured;

a signal-generating component for producing first and second optical signals of distinct wavelengths, the first signal wavelength being such that the signal intensity is altered at the sensor tip in proportion to the presence of the environmental parameter, the second signal wavelength being such that the intensity of the signal is predictably altered at the sensor tip; and

a signal-measuring component for receiving signals from the distribution system, the distribution system comprising;

a plurality of lengths of optical fiber, at least some of said lengths connected in light communicating relationship by abutting the ends thereof, the relationship of the diameters of said abutting optical fibers being such that whenever a group of two or more fibers is connected to a single fiber, the end of said single fiber completely subtends the end of the group of fibers;

a dividing connector for connecting at least three intermediate fibers to the signal-generating component to thereby receive intermediate signals, at least one intermediate signal corresponding to the wavelength of the first signal and one intermediate signal corresponding to the wavelength of the second signal;

a mixing connector for connecting a mixing fiber to said intermediate fibers to thereby receive said intermediate signals and blend them into a single mixed signal, said mixing fiber being of a suitable length to mix the first and second signals into a single mixed signal distributed uniformly across said mixing fiber;

a transmitting connector for connecting a transmitting fiber to said mixing fiber to thereby receive a portion of said mixed signal;

a tip connector for connecting said transmitting fiber and an indicator fiber to tip fiber means for transmitting said mixed signal to the sensor tip and for transmitting a portion of the resulting indicator signal returned from the sensor tip to said indicator fiber, whereby the signal returned from the sensor tip is transmitted to the signal-measuring component via said indicator fiber and the intensity of said intermediate signals corresponding to the first signal is maximized at the dividing connector, the intensity of said intermediate signals corresponding to the first signal being bounded by the transmission of intermediate signals corresponding to the second signal of adequate intensity such that the intensity of the indicator signal of a wavelength corresponding to the wavelength of the second signal received by the signal-measuring component is suitable for monitoring the operation of the distribution system.

14. The distribution system as claimed in claim 13, wherein said tip fiber means includes the single-fiber of the sensor tip.

15. The distribution system as claimed in claim 13, wherein said tip fiber means includes an extension fiber, one end of which is connected to said transmitting fiber and said indicator fiber via said tip connector.

16. The distribution system as claimed in claim 13, wherein said transmitting connector further connects a comparison fiber to said mixing fiber to thereby transmit a portion of said mixed signal to the signal-measuring component.

17. A method for distributing signals in an environmental parameter measuring sensor, the sensor having:

a single-fiber sensor tip that includes means for altering a light signal in accordance with the presence of the environmental parameter to be measured;

a signal-generating component for producing first and second optical signals of distinct wavelengths, the first signal wavelength being such that the signal intensity is altered at the sensor tip in proportion to the presence of the environmental parameter, the second signal wavelength being such that the intensity of the signal is predictably altered at the sensor tip;

a signal-measuring component for receiving signals from the distribution system;

a plurality lengths of optical fibers, at least some of said lengths connected in light communicating relationship by abutting the ends thereof, the relationships of the diameters of said connected optical fibers being such that whenever a group of two or more fibers is connected to a single fiber, the end of said single fiber completely subtends the end of the group of fibers, said method comprising the steps of;

dividing the first and second signals into intermediate signals by connecting at least three intermediate fibers to the signal-generating component such that at least one intermediate signal corresponds to the wavelength of the first signal and one intermediate signal corresponds to the wavelength of the second signal;

mixing said intermediate signals into a mixed signal by connecting a mixing fiber to said intermediate fibers to thereby receive said intermediate signals and blend them into a single mixed signal, said mixing fiber being of a suitable length to mix the first and second signals into a single mixed signal distributed uniformly across said mixing fiber;

transmitting a portion of said mixed signal along a transmitting fiber by connecting said transmitting fiber to said mixing fiber;

transmitting a portion of said mixed signal along a comparison fiber by connecting said comparison fiber to said mixing fiber;

transmitting said mixed signal from said transmitting fiber to the sensor tip by connecting said transmitting fiber to the tip fiber means; and

transmitting a portion of the resulting indicator signal returned from the sensor tip along an indicator fiber by connecting an indicator fiber to the tip fiber means, whereby the signal returned from the sensor tip is transmitted to the signal measuring component via said indicator fiber and the intensity of said intermediate signals corresponding to the first signal is maximized at the dividing connector, the intensity of said intermediate signals corresponding to the wavelength of the first signal being bounded by the transmission of intermediate signals corresponding to the second signal of adequate intensity such that the intensity of the indicator signal of a wavelength corresponding to the wavelength of the second signal received by the signal-measuring component is suitable for monitoring the operation of the distribution system.

18. A method for distributing signals in a sensor that utilizes an analyte-sensitive indicator molecule to monitor the concentration of an analyte, the sensor having:

a signal-generating component for producing first and second optical signals of distinct wavelengths, the first signal wavelength being such that the signal intensity is altered by the indicator molecule in proportion to the presence of the analyte, the second signal wavelength being such that the intensity of the signal is predictably altered by the indicator molecule;

a single-fiber sensor tip that includes the indicator molecule;

a signal-measuring component for receiving signals from the distribution system; and

a plurality of optical fibers of first and second diameters, the second diameter being larger than the first diameter, said method comprising the steps of;

dividing the first and second signals into intermediate signals by connecting at least three intermediate fibers of the first diameter to the signal-generating component such that at least one intermediate signal corresponds to the wavelength of the first signal and one intermediate signal corresponds to the wavelength of the second signal;

mixing said intermediate signals into a mixed signal by connecting a mixing fiber of the second diameter to said intermediate fibers to thereby receive said intermediate signals and blend them into a single mixed signal, said mixing fiber being of a suitable length to mix the first and second signals into a single mixed signal distributed uniformly across said mixing fiber;

transmitting a portion of said mixed signal along a transmitting fiber of the first diameter by connecting said transmitting fiber to said mixing fiber;

transmitting a portion of said mixed signal along a comparison fiber of the first diameter by connecting said comparison fiber to said mixing fiber;

transmitting said mixed signal from said transmitting fiber to the sensor tip by connecting said transmitting fiber to the sensor tip fiber; and

transmitting a portion of the resulting indicator signal returned from the sensor tip to the signal-measuring component by connecting an indicator fiber of the first diameter to the sensor tip, whereby the intensity of said intermediate signals corresponding to the first signal is maximized at the dividing connector, the intensity of said intermediate signals corresponding to the wavelength of the first signal being bounded by the transmission of intermediate signals corresponding to the second signal of adequate intensity such that the intensity of the indicator signal of a wavelength corresponding to the wavelength of the second signal received by the signal-measuring component is suitable for monitoring the operation of the distribution system.