Method of screening and selecting intraperitoneal medication infusion pump candidates

• US 4,911,168 A
• Filed: 01/13/1989
• Issued: 03/27/1990
• Est. Priority Date: 01/13/1989
• Status: Expired due to Fees

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Davis, Mark W.
• Primary Examiner(s): Sykes, Angela D.
• Application Number:
  US07/297,505
• Time in Patent Office: 438 Days
• Field of Search: 128/630, 128/632, 128/637, 128/668, 128/897-898, 128/DIG. 22, 604/49-50, 604/52, 604/266, 424/9
• US Class Current: 600/309
• CPC Class Codes: A61B 5/00 Measuring for diagnostic purposes radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00; Identification of persons

Abstract

A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter is disclosed which seeks to select only those candidates who will have a high degree of resistance to catheter blockage due to fibrotic tissue growth. By checking certain physical parameters in candidates for an implantable catheter, and by declining to implant in those candidates who have higher than desirable levels of the parameters, catheter survival in those patients chosen for implant is maximized. The four parameters used are blood triglyceride level, blood cholesterol level, the level of insulin dosage per day, and mean blood glucose (MBG) level, with the first two being the more accurate parameters.

Claims

1. A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining in a patient the level of at least one parameter from the group of parameters consisting of blood triglyceride level, blood cholesterol level, the level of insulin dosage per day, and mean blood glucose (MBG) level;

comparing the determined level of said at least one parameter with a predetermined maximum value for said at least one parameter to determine whether said at least one parameter is greater than said predetermined maximum value or not; and

providing an indication that the patient is not a suitable candidate for implantation of a catheter if said at least one parameter is greater than said predetermined maximum value.

2. A method as defined in claim 1, wherein said at least one parameter is blood triglyceride level.

3. A method as defined in claim 2, wherein said predetermined maximum value is between approximately 100 mgddl and 125 mg/dl.

4. A method as defined in claim 3, wherein said predetermined maximum value is approximately 120 mg/dl.

5. A method as defined in claim 1, wherein said at least one parameter is blood cholesterol level.

6. A method as defined in claim 5, wherein said predetermined maximum value is between approximately 180 mg/dl and 235 mg/dl.

7. A method as defined in claim 6, wherein said predetermined maximum value is between approximately 200 mg/dl and 215 mg/dl.

8. A method as defined in claim 7 wherein said predetermined maximum value is approximately 200 mg/dl.

12. A method as defined in claim 1, wherein said at least one parameter is mean blood glucose (MBG) level.

13. A method as defined in claim 12, wherein said predetermined maximum value is between approximately 145 mg/dl and 175 mg/dl.

14. A method as defined in claim 13, wherein said predetermined maximum value is approximately 150 mg/dl.

15. A method as defined in claim 1, additionally comprising:

attempting to cause a reduction in said at least one parameter if an indication that the patient is not a suitable candidate for implantation of a catheter is provided due to said at least one parameter being greater than said predetermined maximum value.

9. A method as defined in claim1, wherein said at least one parameter is the level of insulin dosage per day.

10. A method as defined in claim 9, wherein said predetermined maximum value is between approximately 55 Units per day and 85 Units per day.

11. A method as defined in claim 10, wherein said predetermined maximum value is approximately 60 Units per day.

16. A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining the level of triglycerides in the blood of a patient;

comparing the determined level of triglycerides with a predetermined maximum value for triglycerides to determine whether the determined level of triglycerides is greater than said predetermined maximum value for triglycerides or not;

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of triglycerides is greater than sad predetermined maximum value for triglycerides;

determining the level of cholesterol in the blood of a patient;

comparing the determined level of cholesterol with a predetermined maximum value for cholesterol to determine whether the determined level of cholesterol is greater than said predetermined maximum value for cholesterol or not;

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of cholesterol is greater than said predetermined maximum value for cholesterol;

determining the level of insulin dosage per day of a patient;

comparing the determined level of insulin dosage per day with a predetermined maximum valve for insulin dosage per day to determine whether the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day or not;

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day;

determining the level of mean blood glucose (MBG) in the blood of a patient;

comparing the determined level of mean blood glucose with a predetermined maximum value for mean blood glucose to determine whether the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose or not; and

providing an indication (that the patient is not a suitable candidate for implantation of a catheter if the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose.

17. A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining the level of triglycerides in the blood of a patient;

comparing the determined level of triglycerides with a predetermined maximum value for triglycerides to determine whether the determined level of triglycerides is greater than said predetermined maximum value for triglycerides or not;

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of triglycerides is greater than said predetermined maximum value for triglycerides;

determining the level of cholesterol in the blood of a patient;

comparing the determined level of cholesterol with a predetermined maximum value for cholesterol to determine whether the determined level of cholesterol is greater than said predetermined maximum value for cholesterol or not; and

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of cholesterol is greater than said determined maximum value for cholesterol.

18. A method of screening potential recipients of an implantable medication infusion system including a implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining the level of triglycerides in the blood of a patient;

comparing the determined level of triglycerides with a predetermined maximum value for triglycerides to determine whether the determined level of triglycerides is greater than said predetermined maximum value for triglycerides or not; and

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of triglycerides is greater than said predetermined maximum value for triglycerides.

19. A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining the level of cholesterol in the blood of a patient;

comparing the determined level of cholesterol with a predetermined maximum value for cholesterol to determine whether the determined level of cholesterol is greater than said predetermined maximum value for cholesterol or not; and

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of cholesterol is greater than said predetermined maximum value for cholesterol.

20. A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining the level of insulin dosage per day of a patient;

comparing the determined level of insulin dosage per day with a predetermined maximum value for insulin dosage per day to determine whether the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day or not; and

providing an indication that the patient is not a suitable candidate for implantation of a catheter if the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day.

21. A method of screening potential recipients of an implantable medication infusion system including an implanted intraperitoneal catheter to select only those candidates who will have a high degree of resistance to catheter blockage, comprising:

determining the level of mean blood glucose (MBG) in the blood of a patient;

comparing the determined level of mean blood glucose with a predetermined maximum value for mean blood glucose to determine whether the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose or not; and

providing an indication that the patient is no a suitable candidate for implantation of a catheter if the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose.