Assembly for adminstering IV solution

• US 4,911,691 A
• Filed: 08/18/1987
• Issued: 03/27/1990
• Est. Priority Date: 09/21/1984
• Status: Expired due to Term

• Current Assignee: Menlo Care, Inc. (Johnson & Johnson)
• Original Assignee: Menlo Care, Inc. (Johnson & Johnson)
• Inventors: Aniuk, Lawrence M., Dieck, Ronald L., Hardy, Dwayne
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): Daley, Kathleen A.
• Application Number:
  US07/087,132
• Time in Patent Office: 952 Days
• Field of Search: 604/164, 604/166, 604/168, 604/158, 128/343
• US Class Current: 604/164.03
• CPC Class Codes: A61L 29/049 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 29/145 Hydrogels or hydrocolloids
• CPC Class Codes: A61M 25/0009 Making of catheters or other medical or surgical tubes
• CPC Class Codes: C08L 101/00 Compositions of unspecified macromolecular compounds
• CPC Class Codes: C08L 2203/02 for biomedical use
• CPC Class Codes: C08L 2666/02 Organic macromolecular compounds, natural resins, waxes or and bituminous materials

Abstract

An article, suitable for use as a body implant, is made from a novel composition comprising a multiple phase polymer composition comprising:

(a) a first phase which comprises a substantially nonhydrophilic polymeric component; and

(b) a second phase which comprises a hydrophilic polymeric component;

said composition (i) being capable of absorbing water to an extent that it softens with a softening ratio of at least about 2:1 and/or swells with a swelling ratio of at least about 1.3:1; and (ii) when substantially completely hydrated has an energy to break of at least about 700 N-cm/cm³ and a 2.5% Secant modulus of less than about 7,000 N/cm².

Claims

1. An assembly for administering an IV solution to a patient which comprises:

(a) a needle; and

(b) a cannula surrounding the needle, the walls of which cannula are of a multiple phase polymeric composition comprising;

(i) a first phase which is continuous and comprises a substantially non-hydrophilic polymeric component capable of absorbing no more than about 30% water; and

(ii) a second phase which comprises a hydrophilic polymeric component capable of absorbing at least 50% water;

wherein said cannula is capable of absorbing water to an extent that it softens with a softening ratio of at least about 2;

1 and/or swells with a swelling ratio of at least about 1.3;

1; and

when substantially completely hydrated, has a tensile energy to break of at least about 700 N-cm/cm³ and a 2.5% Secant modulus of less than about 7,000 N/cm².

7. An assembly in accordance with claim 1 or claim 2, wherein said multiple phase composition comprises a physical mixture of said polymeric components.

8. An assembly in accordance with claim 1 or claim 2, wherein said composition is crosslinked.

9. An article in accordance with claim 1 or claim 2, wherein the composition has a softening ratio of at least about 6:

1.

10. An article in accordance with claim 9, wherein the composition has a softening ratio of at least about 10:

1.

11. An article in accordance with claim 1 or claim 2, wherein the composition has a swelling ratio of at least about 1.7:

1.

12. An article in accordance with claim 11, wherein the composition has a swelling ratio of at least about 2.0:

1.

13. An article in accordance with claim 1 or claim 2, wherein the composition has a tensile energy to break when hydrated of at least about 1400 N-cm/cm³.

14. An article in accordance with claim 1 or claim 2, wherein the composition has a 2.5% Secant modulus when hydrated of less than about 4,000 N/cm².

2. An assembly for administering an IV solution to a patient which comprises:

(a) a needle; and

(b) a tubular cannula positioned within the needle, the walls of which cannula are of a multiple phase polymeric composition comprising;

(i) a first phase which is continuous and comprises a substantially non-hydrophilic polymeric component capable of absorbing no more than about 30% water; and

(ii) a second phase which comprises hydrophilic polymeric component capable of absorbing at least 50% water;

wherein said cannula is capable of absorbing water to an extent that it softens with a softening ratio of at least about 2;

1 and/or swells with a swelling ratio of at least about 1.3;

1; and

when substantially completely hydrated, has a tensile energy to break of at least about 700 N-cm/cm³ and a 2.5% Secant modulus of less than about 7,000 N/cm².

3. An assembly in accordance with claim 46 or claim 2 wherein said non-hydrophilic polymer component comprises a polymer selected from the group consisting of a polyurethane, an ethylene-vinyl acetate copolymer, an ethylene-ethyl acrylate copolymer, a low crystalline polyamide and an aliphatic polyester.

4. An assembly in accordance with claim 3 wherein the non-hydrophilic polymer component comprises a polyurethane.

5. An assembly in accordance with claim 46 or claim 2, wherein the hydrophilic polymeric component comprises a polymer selected from the group consisting of polyvinyl alcohol, poly(ethylene oxide), polypropylene oxide, poly(ethylene glycol) polypropylene glycol, polytetramethylene oxide, polyvinyl pyrolidene, polyacrylamide, poly(hydroxy ethyl acrylate) and poly(hydroxyethyl methacrylate).

6. An assembly in accordance with claim 5, wherein the hydrophilic polymeric component capable of forming a hydrogel comprises poly(ethylene oxide).