Method for forming a miniaturized biological assembly
First Claim
1. The method of making a miniaturized assembly to facilitate study of biological samples in a liquid medium while under magnification, which comprises the steps of:
- a forming components which are inadequate as to wettablity, relative to the liquid medium, to define a miniaturized capillary environment containing the sample for a time sufficient to prevent deterioration of the sample while it is being studied;
b altering the wettability of the components relative to the liquid medium so that they may define a benign, miniaturized capillary environment containing the sample for a time sufficient to prevent deterioration of the sample while it is being studied; and
c assembling the components to define the benign, miniaturized capillary environment.
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Accused Products
Abstract
A method of making a miniature chamber assembly that provides a miniature capillary environment in which a liquid medium containing microscopic size particulate material can be placed for study under a microscope includes the steps of forming components which are inadequate as to wettability relative to the liquid medium, altering the wettability of the components relative to the liquid medium so that they can provide a miniaturized capillary environment that can contain the liquid medium with particulate material for a time sufficient to prevent deterioration while being studied, and assembling the components to define the miniaturized capillary environment.
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Citations
11 Claims
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1. The method of making a miniaturized assembly to facilitate study of biological samples in a liquid medium while under magnification, which comprises the steps of:
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a forming components which are inadequate as to wettablity, relative to the liquid medium, to define a miniaturized capillary environment containing the sample for a time sufficient to prevent deterioration of the sample while it is being studied; b altering the wettability of the components relative to the liquid medium so that they may define a benign, miniaturized capillary environment containing the sample for a time sufficient to prevent deterioration of the sample while it is being studied; and c assembling the components to define the benign, miniaturized capillary environment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. The method of making a miniature chamber assembly to facilitate study of microscopic size particulate material contained in a medium while under magnification which comprises the steps of:
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a providing two glass plates and forming a thin film of photoresist material on a surface of at least one plate in which the film is of a thickness of 0.25-250 micrometers, b exposing the thin film to a patterned image and removing film material from the glass plate to leave discrete portions of the film in accord with the pattern, c altering the patterned film to render it selectively wettable by the medium, and d superimposing the second glass plate upon the selectively wettable, patterned film to form a system of miniaturized chambers between the plates and bounded by the patterned film. - View Dependent Claims (10, 11)
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Specification