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Measuring with zero volume cell

  • US 4,911,794 A
  • Filed: 06/18/1987
  • Issued: 03/27/1990
  • Est. Priority Date: 06/20/1986
  • Status: Expired due to Term
First Claim
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1. A method for determining the presence of an analyte in a sample suspected of containing said analyte, which comprises:

  • contacting a concentrate of a determinable element capable of being detected with a semiconductive electrode with said electrode in the presence of a liquid assay medium, wherein said determinable element is present in said concentrate in an amount related to the amount of analyte present in said sample;

    reducing the volume of the medium in diffusive communication with said concentrate; and

    detecting said determinable element by means of the effect said determinable element has on said semiconductive electrode.

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