Miniscule droplet dispenser tip

• US 4,917,274 A
• Filed: 09/19/1984
• Issued: 04/17/1990
• Est. Priority Date: 09/27/1983
• Status: Expired due to Fees

• Current Assignee: Sorenson Bioscience Incorporated (Corning Incorporated), David T. Asa
• Original Assignee: ASA Maurice, David T. Asa
• Inventors: Asa, Maurice, Asa, David T.
• Primary Examiner(s): Shaver, Kevin P.
• Assistant Examiner(s): Bollinger, David H.
• Application Number:
  US06/652,750
• Time in Patent Office: 2,036 Days
• Field of Search: 222/420, 222/566, 604/295, 604/299
• US Class Current: 222/420
• CPC Class Codes: B01L 3/0275 Interchangeable or disposable dispensing tips

Abstract

An improved miniscule fluid volume dispenser tip including a tube having an elongated constant diameter small bore disposed at the outlet end thereof with a fluid reservoir disposed at the opposite internal end thereof, the outlet end of the dispenser tip being sharply cut away to reduce surface area to which the dispensed liquid may be attach.

Claims

1. An improved fluid volume dispenser tip comprising an elongated tube, the discharge end of said tube having a constant diameter small bore between 0.3 and 1.0 mm which extends for approximately one-fourth the length of the tube, the outside diameter of the tip of the discharge end of the tube being of a constant diameter to where it is tapered at a sharp acute angle to the discharge opening to reduce the material disposed therearound, and

the opposite end of said tube having an increased diameter tapered internal bore for storage of fluid and an internal diameter substantially greater than said constant bore internal diameter.

2. The fluid volume dispenser tip of claim 1 including a generally decreasing internal diameter for a portion of the length thereof tapering from the fluid storage end of said tube toward the portion of said tube containing said constant diameter bore, the taper of said tip being approximately a 10°

taper.

3. An improved fluid volume dispenser tip comprising:

an elongated tube, one end of said tube having a constant diameter bore portion which extends for approximately one-fourth the length of said tube, said bore being approximately 0.6 mm. in diameter and 1.5 cm. in length, an outside diameter of said one end of the tip being tapered at approximately a 10°

angle to reduce the material comprising the tip around an opening at said one end, the outside diameter of the remainder of the length of the constant diameter bore portion of said tip being a constant diameter, the opposite end of said tube having an increased diameter internal bore for the storage of fluid, said increased bore being substantially greater than said constant diameter bore and decreasing in diameter tapering toward the discharge end of said tube, and

the body of said tube surrounding said internal bores having a generally decreasing outside diameter tapering for a portion of the length thereof from the fluid storage end of said bore to the portion of said tube containing said constant diameter bore.

4. An improved fluid volume dispenser tip comprising an elongated tube, the discharge end of said tube having a substantially constant bore with a diameter less than 1.0 mm. and extending for at least approximately one-fourth the length of the tube and defining a discharge opening in the discharge end, the outside diameter of the tip of the discharge end of the tube being of a substantially constant diameter to where it is tapered to the discharge opening to reduce the material disposed therearound, and

the opposite end of said tube having an increased diameter tapered internal bore for storage of fluid and internal diameter substantially greater than said constant bore internal diameter.

5. In a pipette tip in the form of a single piece hollow shell of translucent material having a length between first and second ends thereof, said first end having an opening therein for discharging fluid therethrough in response to positive displacement of air within the shell, and said second end adapted to be connected to a micropipettor capable of creating that displacement of air, the improvement comprising:

a first segment of the length of the shell adjacent said first end and extending therefrom a significant finite length with a substantially constant inside diameter bore therein of less than one millimeter and a substantially uniform outside diameter therealong except for a portion of said first segment immediately adjacent said first end which is tapered from the uniform outside diameter toward the discharge opening at an extreme end of said constant inside diameter bore, and

a second segment of the length of the shell adjacent said second end extending therefrom a significant distance and having a decreasing internal diameter opening as a function of distance away from said second end that is in fluid communication with said constant inside diameter bore.

6. The improved pipette tip according to claim 5 wherein said first segment of the shell length is at least approximately one-fourth of the length of said shell.