Polysubstituted aryl acridinium esters
First Claim
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1. A luminescent compound comprising a polysubstituted aryl acridinium ester selected from the group having the following structure:
- ##STR5## where R1 is an alkyl, alkenyl, alkynyl, or aryl group;
R2, R3, R5, or R7 are a hydrogen, amino, carboxyl, hydroxyl, alkoxyl, nitro, or halide group;
R4 or R8 are an alkyl group;
R6 represents the following substituent;
space="preserve" listing-type="equation">R.sub.6 =-R.sub.9 -R.sub.10where R9 is not required but if present is an alkyl, aryl, or aralkyl group, and R10 is selected from the following;
##STR6## X is CH3 SO4-, OSO2 F-, a halide, OSO2 CF3-, OSO2 C4 F9-, ##STR7## R is alkyl, aryl, aralkyl; and
finally R5, R6, and R7 substituent positions on the phenoxy ring are interchangeable.
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Abstract
The present invention relates to novel acridinium esters which are useful as luminescent labels in specific binding assays such as immunoassays or nucleic acid hybridization assays. More particularly, polysubstituted aryl acridinium esters are highly stable labels for use in a chemiluminescent immunoassay.
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2 Claims
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1. A luminescent compound comprising a polysubstituted aryl acridinium ester selected from the group having the following structure:
- ##STR5## where R1 is an alkyl, alkenyl, alkynyl, or aryl group;
R2, R3, R5, or R7 are a hydrogen, amino, carboxyl, hydroxyl, alkoxyl, nitro, or halide group;
R4 or R8 are an alkyl group;
R6 represents the following substituent;
space="preserve" listing-type="equation">R.sub.6 =-R.sub.9 -R.sub.10where R9 is not required but if present is an alkyl, aryl, or aralkyl group, and R10 is selected from the following;
##STR6## X is CH3 SO4-, OSO2 F-, a halide, OSO2 CF3-, OSO2 C4 F9-, ##STR7## R is alkyl, aryl, aralkyl; and
finally R5, R6, and R7 substituent positions on the phenoxy ring are interchangeable. - View Dependent Claims (2)
- ##STR5## where R1 is an alkyl, alkenyl, alkynyl, or aryl group;
Specification