High tack drug patch

• US 4,919,648 A
• Filed: 05/20/1988
• Issued: 04/24/1990
• Est. Priority Date: 08/18/1983
• Status: Expired due to Term

• Current Assignee: Drug Delivery Systems Incorporated
• Original Assignee: Drug Delivery Systems Incorporated
• Inventors: Sibalis, Dan
• Primary Examiner(s): Hindenburg, Max
• Assistant Examiner(s): Shay, Randy
• Application Number:
  US07/196,663
• Time in Patent Office: 704 Days
• Field of Search: 128/639, 128/640, 128/641, 128/798, 128/802, 128/803, 604/20
• US Class Current: 604/20
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir

Abstract

A transdermal drug patch for delivering at least one drug to a patient through the skin comprises:

(a) At least two electrode constructions separated from each other;

(b) Drug reservoir means in at least one of the electrode constructions;

(c) An electrical circuit including a power source, electrodes constructions with conductive elements, and reservoir means connected together;

(d) Optional cover means; and

(e) Adhesive means for affixing the patch to the patient'"'"'s skin, augmented by a plurality of isolated spots of high tack gel, either in arrays or random positions, whereby the patch is more easily removed and replaced than if the adhesive means were homogeneous.

Claims

1. A transdermal drug patch for delivering at least one drug to a patient through the skin comprising:

at least two electrodes forming said patch and separated from each other, each electrode including a conductive element;

drug reservoir means, in at least one of said electrodes;

a circuit, including a power source, for supplying power to and connected to said electrodes at such conductive elements and said reservoir means; and

adhesive means for affixing said patch to the skin, this adhesive means augmented by a plurality of isolated spots of high tack gel traversing the drug reservoir means extending from the bottom of the patch to at least one electrode above the drug reservoir means, whereby the patch is more easily removed and replaced than if the adhesive means were homogeneous, and whereby upon adherence the drug is delivered through the skin.

2. A transdermal drug patch as in claim 1, wherein said electrodes are generally of the same structure.

3. A transdermal drug patch as in claim 1, wherein said electrodes are of different structure.

4. A transdermal drug patch as in claim 1, wherein said electrodes are of different size.

5. A transdermal said drug patch as in claim 1, wherein at least two of said electrodes include said drug reservoir means and each said drug reservoir means contains different said drugs.

6. A transdermal drug patch as in claim 1, wherein the high tack gel spots are elongated in shape and comprise an adhesive gel of greater tack than the adhesive means for affixing the patch to the skin.

7. A transdermal drug patch as in claim 1, wherein the high tack gel spots are substantially spherical and comprise an adhesive gel of greater tack than the adhesive means for affixing the patch to the skin.

8. A transdermal drug patch as in claim 1, wherein the high tack gel spots are aligned in uniform rows.

9. A transdermal drug patch as in claim 1, wherein the high tack gel spots are uniformly placed.

10. A transdermal drug patch as in claim 1, further comprising cover means at least partially enclosing the reservoir means.