Synergistic biocides of certain nitroimidazoles and aldehydes

• US 4,920,141 A
• Filed: 02/24/1988
• Issued: 04/24/1990
• Est. Priority Date: 10/06/1986
• Status: Expired due to Fees

• Current Assignee: Petrolite Corporation (Baker Hughes Company)
• Original Assignee: Petrolite Corporation (Baker Hughes Company)
• Inventors: Jones, Douglas S., Horstmann, Dennis G.
• Primary Examiner(s): Robinson, Allen J.
• Application Number:
  US07/159,793
• Time in Patent Office: 790 Days
• Field of Search: 514/398, 514/697, 514/705
• US Class Current: 514/398
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 35/02 containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals
• CPC Class Codes: A01N 43/50 1,3-Diazoles; Hydrogenated 1,3-diazoles

Abstract

A mixture of bactericides of nitroimidazoles, particularly 1,2-dimethyl-5-nitro-1H-imidazole, or salts thereof and aldehydes, particularly glutaraldehyde and formaldehyde, has been found to exhibit synergistic results in inhibiting the growth of sulfate-reducing bacteria.

Claims

1. A bactericidal composition useful in treating industrial process water to inhibit and control the growth of sulfate-reducing bacteria comprising a synergistic bactericidally effective amount of a mixture of (a) a water-soluble salt of metronidazole, dimetridazole, secnidazole or ipronidazole and (b) glutaraldehyde, the weight ratio of component (a) to component (b) being between about 1:

2 to 1;

100.

2. The composition of claim 1 where in the salt is a strong acid addition salt.

3. The composition of claim 2 wherein the salt is the hydrochloride salt.

4. The composition of claim 1 wherein component (a) is the water-soluble salt of metronidazole.

5. A method of inhibiting the growth of bacteria in an aqueous medium comprising adding to an aqueous medium comprising reducing bacteria a synergistic bactericidally effective amount of a mixture of (a) a water-soluble salt of metronidazole, dimethridazole, secnidazole or ipronidazole and (b) glutaraldehyde, the weight ratio of component (a) to component (b) being between about 1:

2 to 1;

100.

6. The method of claim 5 wherein the salt is a strong acid addition salt.

7. The method of claim 6 wherein the salt is the hydrochloride salt.

8. The method of claim 5 wherein component (a) is the water-soluble salt of metronidazole.