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System for delayed and pulsed release of biologically active substances

  • US 4,921,757 A
  • Filed: 09/03/1987
  • Issued: 05/01/1990
  • Est. Priority Date: 04/26/1985
  • Status: Expired due to Term
First Claim
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1. A composition of for controlled release of entrapped substances comprising:

  • a permeable polymeric matrix,liposomes located within said matrix, anda first substance entrapped within said liposomes, anda phospholipase located in said matrix exterior to said liposomes and bound to said matrix.

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