Arrangement for delivering medications in an implantable medical device

• US 4,922,926 A
• Filed: 10/11/1988
• Issued: 05/08/1990
• Est. Priority Date: 10/16/1987
• Status: Expired due to Term

• Current Assignee: Pacesetter AB
• Original Assignee: Siemens AG
• Inventors: Botvidsson, Lars, Hirschberg, Jakub, Fahlstroem, Ulf
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): GETZOW, SCOTT M
• Application Number:
  US07/255,545
• Time in Patent Office: 574 Days
• Field of Search: 128/784, 128/785, 128/786, 128/419 P, 604/93, 604/175, 604/9, 604/185, 604/20, 604/21
• US Class Current: 607/120
• CPC Class Codes: A61F 2/30771 applied in original prostheses, e.g. holes or grooves
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/30803 inclined obliquely
• CPC Class Codes: A61F 2002/3081 inclined obliquely with respect to each other
• CPC Class Codes: A61F 2002/30817 Intersecting or overlapping blind bores
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: A61N 1/0568 with drug delivery
• CPC Class Codes: A61N 1/37512 Pacemakers

Abstract

An arrangement for delivering medications in an implantable medical device, such as a heart pacemaker, has at least two containers or receptacles for the medication disposed below the surface of a portion of the implanted device, each container terminating in an opening having the size of a pore in the surface of the implanted device to permit the medication to be delivered from the container to surrounding tissue. The structure permits the medication to be delivered at specific regions of tissue, and in a manner which permits control of the medication dose.

Claims

1. An arrangement for delivering medication in an implantable medical device, said device having a plurality of surface regions, said arrangement comprising:

at least two containers, said containers including means for storing medication disposed in said implantable medical device at at least one of said surface regions, each of said containers being in communication with said at least one surface region via an opening in said surface region having the size of a pore adapted to dispense medication from the container to tissue surrounding said surface region.

2. An arrangement as claimed in claim 1, wherein each of said containers has a longitudinal axis, and wherein said longitudinal axes of said containers are disposed at respectively different angles with respect to said at least one surface region.

3. An arrangement as claimed in claim 1, wherein said containers are conical.

4. An arrangement as claimed in claim 1, wherein each of said containers consists of at least two intersecting blind holes.

5. A heart pacemaker system comprising:

a housing;

an electrode lead;

means for connecting said electrode lead to said housing;

means disposed in said housing and electrically connected to said electrode lead via said means for connecting for electrically stimulating body tissue;

a stimulation delivering tip disposed at a distal end of said electrode lead remote from said housing;

each of said housing, said means for connecting and said tip having a surface; and

means disposed in at least one of said housing, said means for connecting, and said tip, for delivering medication to surrounding tissue comprising at least two containers adapted for storing medication, each of said containers having a pore-sized opening in communication with the respective surface of said housing, said means for connecting or said tip adapted for delivering medication from the container to said tissue.

6. A heart pacemaker system as claimed in claim 5, further comprising means disposed at said distal end of said electrode lead for fastening said distal end of said electrode lead to said surrounding tissue, said means for fastening having a surface, and means for delivering medication disposed in said means for fastening.

7. A heart pacemaker system as claimed in claim 5, further comprising a ring electrode on said electrode lead spaced from said distal end and forming a bipolar electrode with said tip, said ring electrode having a surface and having means for delivering medication disposed therein.

8. A heart pacemaker system as claimed in claim 5, further comprising means for clamping said electrode lead to a vein, said means for clamping having a surface and further comprising means for delivering medication in said means for clamping.

9. A heart pacemaker system as claimed in claim 5, wherein each of said containers has a longitudinal axis, and wherein said longitudinal axes of said containers are disposed at respectively different angles with respect to the surface with which said containers communicate.

10. A heart pacemaker system as claimed in claim 5, wherein said containers are conical.

11. A heart pacemaker system as claimed in claim 5, wherein said containers consist of two intersecting blind holes.