Removable inflatable intragastrointestinal device for delivering beneficial agents
First Claim
1. A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising:
- (a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state;
(b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated;
(c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract.
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Accused Products
Abstract
A removable inflatable beneficial agent delivery device that is adapted to reside in the stomach for a prolonged time period. The device comprises (1) an inflatable member which in its deflated state can be inserted into the stomach via a naso-gastric tube and which in its inflated state resides comfortably in the stomach but cannot pass through the pyloric sphincter, (2) an inflation tube connected to the inflatable member by which the inflatable member can be inflated from outside the body and which is dropped into the stomach after inflation, and (3) one or more agent-containing cartridges that are carried exteriorly on the inflatable member or the inflation tube and are capable of delivering agent to the gastrointestinal tract over a prolonged time period.
458 Citations
9 Claims
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1. A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising:
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(a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; (c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract. - View Dependent Claims (2, 9)
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3. A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising:
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(a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; (c) at least one cartridge member carried on the exterior of the inflatable member and/or the inflation tube, said cartridge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract, and (d) a magnetic body carried proximate to said other end of the inflation tube and providing a means by which the inflation tube may be magnetically retrieved from the stomach via the esophagus and mouth.
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4. A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising:
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(a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; and (c) at least one cartridge member carried on the exterior of the inflation tube, said cartidge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract and having an opening through it and being strung on the inflation tube via the opening. - View Dependent Claims (5)
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6. A removable inflatable intragastrointestinal beneficial agent delivery device adapted to reside within a stomach comprising:
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(a) an inflatable member which is sized and shaped to pass through the esophagus in its deflated state and reside within the stomach and not pass through the pyloric sphincter in its inflated state said inflatable member having an opening in it that defines a cavity; (b) a hollow inflation tube for inflating the inflatable member once the inflatable member is within the stomach, one end of which is operably connected to the inflatable member and the other end of which carries a valve, said inflation tube having a length sufficient to extend from the mouth through the esophagus and into the stomach, providing a means by which the inflatable member may be inflated from outside the body and being adapted to reside within the stomach after the inflatable member is inflated; and (c) at least one cartridge member carried in the cavity of the inflatable member, said cartridge member containing a beneficial agent and being capable of releasing said agent into the gastrointestinal tract. - View Dependent Claims (7, 8)
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Specification