Monoclonal antibody against human pneumocystis carinii

• US 4,925,800 A
• Filed: 12/04/1986
• Issued: 05/15/1990
• Est. Priority Date: 12/04/1986
• Status: Expired due to Term

• Current Assignee: United States Department Of Health And Human Services (Government of the United States of America)
• Original Assignee: United States Department Of Health And Human Services (Government of the United States of America)
• Inventors: Masur, Henry, Kovacs, Joseph A.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Krupen, Karen I.
• Application Number:
  US06/938,716
• Time in Patent Office: 1,258 Days
• Field of Search: 435/68, 435/172.2, 435/240.27, 935/104, 935/110, 530/387
• US Class Current: 530/388.4
• CPC Class Codes: C07K 16/14 against material from fungi, algea or lichens

Abstract

Hybridomas producing antibodies having specific binding affinity against Pneumocystis carinii having been obtained and a method and kit for detecting P. carinii infection in humans having been described.

Claims

1. A monoclonal antibody having specific binding affinity against human Pneumocystis carinii, said monoclonal antibody being 2G2.

2. A composition comprising a mixture of monoclonal antibodies 2G2, 6B8 and 7D7.

3. A hybridoma producing monoclonal antibodies having specific binding affinity against human Pneumocystis carinii, said hybridoma selected from the group consisting of HB9235, HB9236 and HB9237.

4. The hybridoma of claim 3 being HB9235.