Encapsulation composition for use with chewing gum and edible products

• US 4,929,447 A
• Filed: 06/29/1987
• Issued: 05/29/1990
• Est. Priority Date: 01/07/1986
• Status: Expired due to Term

• Current Assignee: Cadbury Adams USA LLC (Mondelez International, Inc.)
• Original Assignee: Warner-Lambert Company (Pfizer Inc.)
• Inventors: Yang, Robert K.
• Primary Examiner(s): Page, Thurman K.
• Application Number:
  US07/067,894
• Time in Patent Office: 1,065 Days
• Field of Search: 424/440, 424/441, 424/78, 426/5, 426/6, 426/99, 426/96, 426/98
• US Class Current: 424/440
• CPC Class Codes: A23G 4/02 Apparatus specially adapted for manufacture or treatment of chewing gum
• CPC Class Codes: A23G 4/06 characterised by the composition containing organic or inorganic compounds
• CPC Class Codes: A23G 4/20 Composite products, e.g. centre-filled , multi-layer, laminated
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/16 Taste affecting agent
• CPC Class Codes: A23V 2200/224 Encapsulating agent
• CPC Class Codes: A23V 2250/022 Acetic acid
• CPC Class Codes: A23V 2250/18 Lipids
• CPC Class Codes: A23V 2250/1886 Stearic acid
• CPC Class Codes: A23V 2250/2482 Aspartam
• CPC Class Codes: A23V 2250/26 Saccharin
• CPC Class Codes: A23V 2250/30 Other Organic compounds
• CPC Class Codes: A23V 2250/628 Saccharose, sucrose
• CPC Class Codes: A23V 2250/6406 Glycerol
• CPC Class Codes: A23V 2250/642 Sorbitol

Abstract

The present invention is method and composition for protecting an active ingredient and providing controlled release therefor, especially in a chewing gum composition, which includes a high molecular weight polyvinyl acetate blended with a hydrophobic plasticizer which forms a film with the high molecular weight polyvinyl acetate in the absence of an added solvent therefor. The active ingredient, such as the artificial sweetener aspartame, is blended into the encapsulating composition as, for example, by melt blend which can then be cooled to a solid and ground into particulate. The encapsulated active ingredient can then be used in a composition for ingestion by a human in the form of, for example, a chewing gum with extended shelf life and highly controlled release of the active ingredient.

Claims

1. An edible solvent-free encapsulation composition for protecting against moisture comprising:

a blend of high molecular weight polyvinyl acetate having a molecular weight of about 20,000 to about 100,000 MWU and a hydrophobic plasticizer, said polyvinyl acetate and hydrophobic plasticizer being present in a ratio of 5;

1 to about 1;

5 and wherein said blend is capable of forming an encapsulating film when mixed in a melt blend.

2. The composition of claim 1 wherein the molecular weight of said polyvinyl acetate is from about 30,000 MWU to about 60,000 MWU.

3. The composition of claim 1 wherein said hydrophobic plasticizer comprises a mono-, di- or triglyceride or ester derivatives thereof, said plasticizer having a fatty acid chain of from about 16 to about 20 carbon atoms.

4. The composition of claim 1 wherein the ratio is from about 2:

1 to about 1;

2.

5. The composition of claim 1 wherein said encapsulation is a film formed on an active ingredient.

6. The composition of claim 5 wherein said active ingredient is selected from the group consisting soluble dietary fibers, bio-effecting agents, and mixtures thereof.

7. An edible product comprising an encapsualted active ingredient which is protected from moisture deterioration and which exhibits controlled release, wherein said active ingredient is selected from the group consisting of soluble dietary fibers, bio-effecting agents, and mixtures thereof and said encapsulant is solvent-free and comprises a blend of high molecular weight polyvinyl acetate and a hydrophobic plasticizer in an edible matrix wherein the active ingredient and encapsulant are mixed in a melt blend.

8. The product of claim 7 wherein said polyvinyl acetate has a molecular weight of from about 20,000 MWU to about 100,000 MWU and said hydrophobic plasticizer is selected from the group consisting of mono-, di- and triglycerides having a fatty acid chain length of from about 16 to about 22 carbon atoms.

9. The product of claim 8 wherein said product is a confectionary product.

10. The product of claim 8 wherein said product is a pharmaceutical product.

11. The product of claim 7 wherein said soluble dietary fiber is selected from the group consisting of non-cellulosic polysaccharides, pectin, guar gum, locust bean gum, algal polysaccharides, cellulose, hemi-celluloses, lignin, and mixtures thereof.

12. The product of claim 7 wherein said active ingredient is a bio-effecting agents selected from the group consisting of mineral supplements, analgesics, antipyretics, antiarrhythmics, ion exchange resins, appetite suppressants, vitamins, anti-inflammatory substances, coronary dilators, cerebral dilators, peripheral vasodilators, anti-infectives, psychotropics, antimanics, stimulants, antihistamines, laxatives, decongestants, gastrointestinal sedatives, antidiarrheal preparations, antianginal drugs, vasodilators, anti-hylpertensive drugs, vasoconstrictors and migrane treatments, antibiotics, tranquilizers, antipsychotics, antitumor drugs, anticoagulants and antithrombotic drugs, hypnotics, sedatives, anti-emetics, anti-nauseants, anticonvulsants, neuromuscular drugs, hyper and hypoglycaemic agents, thyroid and antithyroid preparations, diuretics, antispasmodics, uterine relaxants, nutritional additives, antiobesity drugs, anabolic drugs, erythropoietic drugs, antiasthmatics, expectorants, cough suppressants, mucolytics, anti-uricemic drugs and mixtures thereof.