Method for detecting cancerous tissue using visible native luminescence
First Claim
1. A method for determining if tissue is cancerous comprising:
- a. exciting a tissue to be examined with a beam of light, andb. comparing the visible native luminescence emitted from the tissue with the visible native luminescence emitted from tissue whose condition is known.
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Abstract
A method and apparatus for detecting the presence of cancerous tissue using visible luminescence. The tissue to be examined is excited with a beam of monochromatic light that causes the tissue to fluoresce over a spectrum of wavelengths. The intensity at which the excited tissue fluoresces can be measured either over a spectrum or at a predetermined number of preselected wavelengths. By determining the wavelength(s) at which maximum intensity(ies) are attained for the tissue in question and by comparing these peak wavelengths, either visually or electronically, to the peak wavelength(s) derived from a known non-cancerous tissue, or by comparing the spectrum of the excited tissue with the spectrum of a known noncancerous tissue one can determine the carcinomatoid status of the tissue in question. The invention is based on the discovery that the visible luminescence spectra for cancerous and non-cancerous tissue are substantially different and that the differences are such that visible luminescence from tissue can be used to detect the presence of cancer.
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9 Claims
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1. A method for determining if tissue is cancerous comprising:
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a. exciting a tissue to be examined with a beam of light, and b. comparing the visible native luminescence emitted from the tissue with the visible native luminescence emitted from tissue whose condition is known.
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2. A method for determining if tissue is cancerous comprising:
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a. exciting a tissue to be examined with a beam of light. b. observing the visible native luminescence emitted from the tissue at least two wavelengths, and c. determining if the tissue is cancerous in accordance with said measurements.
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3. A method for detecting cancerous tissue comprising:
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a. exciting a tissue to be examined with a beam of light that is substantially monochromatic, and then b. comparing the resulting native luminescence spectrum with the native luminescence spectra for native normal and cancerous tissue.
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4. A method for detecting cancerous tissue comprising:
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a. exciting a tissue to be examined with a beam of light that is at least substantially monochromatic. b. measuring the intensity of the visible native luminescence emitted from the tissue at least two wavelengths, and c. determining if the tissue is cancerous in accordance with said measurements. - View Dependent Claims (5, 6, 7, 8)
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9. A method for detecting cancerous tissue comprising:
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a. exciting a tissue to be examined with a beam of monochromatic light. b. generating a luminescence spectrum native of light emitted by the tissue, and c. comparing the luminescent spectrum with a luminescent spectrum for a known normal tissue.
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Specification