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Pressure-sensitive medical sealant

  • US 4,931,282 A
  • Filed: 11/25/1987
  • Issued: 06/05/1990
  • Est. Priority Date: 11/25/1987
  • Status: Expired due to Term
First Claim
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1. A medical sealant composition comprising:

  • (a) a crosslinked, swellable polymeric matrix formed by a free-radical polymerization of at least one polymerizable monomeric species wherein at least 50 percent by weight of the monomeric component is comprised of one or more N-vinyl lactams, and a crosslinker which is a multi-ethylenically unsaturated compound with the ethylenic groups being vinyl, allyl, or methallyl groups bonded to nitrogen or oxygen atoms, said N-vinyl lactam monomer being present in a concentration of about 5 to 99.9 percent by weight of the polymeric matrix precursor and said crosslinker being present in a concentration of about 0.02 to 5.0 percent by weight of said N-vinyl lactam monomer;

    (b) a plasticizing solution present in a concentration of between about 55 and less than about 95 percent by weight of said medical sealant composition; and

    (c) an antimicrobial present in a concentration of between about 0.01 and 10 percent by weight of said medical sealant composition;

    which composition is formulated so as to have a T-Peel value of at least about 3 g/cm when measured on low density polyethylene, as described herein.

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