Method for preventing blood coaguli from being formed in the extra-body circuit of dialysis apparatus and composition useful therefor
First Claim
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1. A method for preventing the formation of blood coaguli in an extracorporeal hemodialysis apparatus, said apparatus comprising a first means for transporting blood from a patient to a dialyzer, a hemodialysis membrane for dialyzing the blood transported thereto, and a second means for returning the dialyzed blood to the patient, which comprises introducing defibrotide into the blood in said first means upstream of the dialyzer in an amount effective to prevent the formation of blood coaguli in said apparatus.
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Abstract
The introduction of Defibrotide, as a bolus or by infusion, upstream of the dialysis membrane of the extra body circuit of apparatus for the extra-body dialysis prevents coaguli from being formed in the blood stream.
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8 Claims
- 1. A method for preventing the formation of blood coaguli in an extracorporeal hemodialysis apparatus, said apparatus comprising a first means for transporting blood from a patient to a dialyzer, a hemodialysis membrane for dialyzing the blood transported thereto, and a second means for returning the dialyzed blood to the patient, which comprises introducing defibrotide into the blood in said first means upstream of the dialyzer in an amount effective to prevent the formation of blood coaguli in said apparatus.
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