Patient-fillable and non-invasive hypodermic injection device assembly

• US 4,940,460 A
• Filed: 12/12/1988
• Issued: 07/10/1990
• Est. Priority Date: 06/19/1987
• Status: Expired due to Term

• Current Assignee: Bioject Incorporated
• Original Assignee: Bioject Incorporated
• Inventors: Casey, I., James P., Morrow, J. Thomas
• Primary Examiner(s): Yasko, John D.
• Application Number:
  US07/283,737
• Time in Patent Office: 575 Days
• Field of Search: 604/143, 604/142, 604/141, 604/134, 604/131, 604/130, 604/218, 604/68, 604/69, 604/70, 604/187, 604/71
• US Class Current: 604/143
• CPC Class Codes: A61M 2005/3132 having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

The assembly includes an injection device which includes a housing having an ampule-receiving chamber, a gas charge, and means for delivering a predetermined amount of gas to the ampule-receiving chamber. The device includes an injection-counting ring which is received in a groove extending about the housing wherein the ring includes a counting mechanism thereon and is constructed to allow one-way only rotation thereof relative to the housing. The patient-fillable ampule of the invention includes an ampule body having a plunger end and an orifice end, a medication retaining cavity and an elongate plunger which is received in one end of the cavity. An orifice-bearing end cap is fixed to the orifice end of the body. A truncated hypodermic needle is received in the end cap. A removable needle is provided for filling the ampule and allows use of the ampule as a conventional syringe. The ampule is attached to the hypodermic device by means of an ampule sleeve which extends about the ampule body along the length thereof and which cooperates with a retainer collar located on the device.

Claims

1. A hypodermic syringe comprising:

an ampule body having a plunger end and an orifice end, said body having a generally elongate cylindrical form with an outer wall of predetermined diameter and an inner wall defining a medication retaining cavity, a flange which is a continuation of said inner wall which is located at said orifice end and extends axially outward therefrom, said flange having an outer wall which is located intermediate said body inner wall and said body outer wall;

an elongate plunger, one end thereof having a seal-carrying groove formed about the periphery thereof and being received in said medication retaining cavity with a seal received in said groove;

an orifice-bearing end cap fixed to said orifice end, said end cap having a generally cylindrical form including a medication-receiving portion extending axially into said medication retaining cavity at one end thereof, said end cap having a groove extending about said medication-receiving portion at the base thereof, said groove being conformal with said flange on said body;

a truncated hypodermic needle received in said end cap and having a channel extending therethrough, said channel communicating with the narrower end of said bore;

a filling needle having connecting means thereon; and

a removable external fill adaptor having a receptacle on one end thereof for receiving said end cap therein and a bore extending therethrough, said bore being aligned with said truncated hypodermic needle on said end cap, means on the other end of said adaptor cooperating with said connecting means for securing said filling needle to said adaptor.

2. The hypodermic syringe of claim 1 wherein said filling needle is a conventional hypodermic needle and said connecting means includes a luer lock fitting.

3. The hypodermic syringe of claim 1 wherein said truncated hypodermic needle is co-terminal with the other end of said end cap.

4. The hypodermic syringe of claim 1 wherein said fill adaptor is constructed and arranged to be removed from the syringe when the syringe is used with a powered, non-invasive hypodermic injection device and to be retained on the syringe when the syringe is used to provide an invasive injection.

5. The hypodermic syringe of claim 1 wherein the syringe is used with a non-invasive hypodermic injection device and includes attachment means for securing the syringe to the device, said attachment means including an elongate ampule sleeve which extends about said ampule body along the length thereof, one end of said sleeve being located adjacent said plunger end of said body, the other end of said sleeve being located adjacent the orifice end of said body, said attachment means being constructed and arranged to grasp said end cap.

6. The assembly of claim 5 wherein said sleeve has lugs spaced about the periphery of one end thereof.

7. The assembly of claim 6 wherein said ampule body has medication-volume indicia thereon and said sleeve has at least one wasted area along a portion thereof for providing a viewing window for said indicia.

8. A patient-fillable ampule and a non-invasive hypodermic injection device assembly comprising:

an injection device including a housing having an ampule-receiving chamber, a gas charge, and means for delivering a predetermined amount of gas to said ampule-receiving chamber; and

a patient-fillable ampule therefore comprising;

an ampule body having a plunger end and an orifice end, said body having a generally elongate cylindrical form with an outer wall of predetermined diameter and an inner wall defining a medication retaining cavity, a flange which is a continuation of said inner wall which is located at said orifice end and extends axially outward therefrom, said flange having an outer wall which is located intermediate said body inner wall and said body outer wall;

an elongate plunger, one end thereof having a seal-carrying groove formed about the periphery thereof and being received in said medication retaining cavity with a seal received in said groove and the other end thereof formed into a broadened head;

an orifice-bearing end cap fixed to said orifice end, said end cap having a generally cylindrical form of substantially the same outside diameter as said outer wall predetermined, larger diameter along a first length thereof and a stepped-down, smaller diameter along a second length thereof, said end cap including a medication-receiving portion extending axially from the larger diameter end thereof into said medication retaining cavity, said medication receiving portion having a truncated conical bore therein with the wider end of said bore located in said medication retaining cavity, said end cap having a groove extending about said medication receiving portion at the base of said medication receiving portion, said groove being conformal with said flange on said body;

a truncated hypodermic needle received in said end cap at the smaller diameter end thereof and having a channel extending therethrough, said channel communicating with the narrower end of said bore; and

attachment means including an elongate ampule sleeve for attaching said ampule to said device which extends about said ampule body along the length thereof, one end of said sleeve being located adjacent said plunger end of said body, the other end of said sleeve being located adjacent said orifice end and being constructed and arranged to grasp said end cap about said stepped-down diameter.

9. The assembly of claim 8 wherein said truncated hypodermic needle is co-terminal with the smaller diameter end of said end cap and which further includes a filling needle having connecting means thereon and a removable, external fill adaptor having a receptacle on one end thereof for receiving said end cap therein, a bore extending therethrough, said bore being aligned with said truncated hypodermic needle on said end cap and means on the other end of said adaptor cooperating with said connecting means for securing said filling needle to said fill adaptor.

10. The hypodermic syringe of claim 9 wherein said filling needle is a conventional hypodermic needle and said connecting means includes a luer lock fitting.

11. The hypodermic syringe of claim 9 wherein said fill adaptor is constructed and arranged to be removed from the syringe when the syringe is used with a powered, non-invasive hypodermic injection device and to be retained on the syringe when the syringe is used to provide an invasive injection.

12. The assembly of claim 8 wherein said ampule body has medication-volume indicia thereon and said sleeve has at least one wasted area along a portion thereof for providing a viewing window for said indicia.

13. The assembly of claim 8 wherein said device includes a retainer collar located at an end of said housing for retaining said sleeve and said ampule on said housing, said sleeve having lugs spaced about the periphery of one end thereof and said collar having lug-receiving grooves therein.

14. The assembly of claim 8 wherein said device includes

an elongate, hollow housing having said ampule-receiving chamber at one end thereof, a pressure chamber at the other end thereof and a partition located between said chambers, said partition having a gas-delivery passage extending therethrough;

said pressure chamber having said gas charge and a valve assembly therein, said valve assembly including;

a valve body having a cavity therein, said cavity including a valve-shaft receiving portion extending from one side of said body to the other side thereof and a gas-passage portion;

a valve end cap secured to the other side of said body having a recess for receiving an end of a gas-charge containing cartridge and a puncture pin located in said recess for piercing said cartridge received in said pressure chamber to release said gas charge;

a poppet valve having a valve head for closing the cavity on the other side of said valve body, a valve shaft received in said cavity and extending therethrough to said one side of said valve body;

a rocker-arm support fixed to said one side of said valve body, a rocker arm pivotably secured at one end thereof to said rocker-arm support with the other, free end, of said rocker arm extending through a slot in the side of said housing to the exterior thereof, and an elongate actuator lever secured to the free end of said rocker arm and extending along the exterior of said housing, said rocker arm and said rocker-arm support being constructed and arranged to provide shiftable contact between said poppet valve shaft and said rocker arm to shift said poppet valve to an open position with movement of said lever towards said housing;

a gas transfer tube extending between said gas-delivery passage and said valve body cavity for directing a gas charge to said ampule-receiving chamber when said poppet valve is opened;

an ampule plunger-driving piston shiftably located in said ampule-receiving chamber; and

an ampule retaining collar located on said one end of said housing for securing an ampule to said housing, said collar having ampule sleeve bayonet-receiving grooves therein for receiving a bayonet lug on an ampule sleeve.

15. The assembly of claim 14 which further includes an injection-counting ring received in a groove extending about said housing, said ring having alternating injection allowing/preventing notches formed about the periphery thereof and including means to allow one-way only rotation of said ring relative to said housing.