Drug delivery device

• US 4,942,883 A
• Filed: 09/29/1987
• Issued: 07/24/1990
• Est. Priority Date: 09/29/1987
• Status: Expired due to Term

• Current Assignee: Avitar, Inc.
• Original Assignee: Martin H. Newman
• Inventors: Newman, Martin H.
• Primary Examiner(s): Hindenburg, Max
• Assistant Examiner(s): LACYK, JOHN P
• Application Number:
  US07/102,540
• Time in Patent Office: 1,029 Days
• Field of Search: 128/798, 128/799, 128/801, 128/803, 604/20, 424/449
• US Class Current: 607/152
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0444 Membrane
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428

Abstract

A transdermal medication delivery system in which a housing includes a power source for supplying programmed current pulses to an electrical current path which includes an electrically charged medication and a body location at which the medication is placed. The level of the current pulses and the time over which they are provided is controlled to deliver a predetermined dosage of the medication to the body location at a predetermined rate.

Claims

1. A self-contained transdermal medication delivery system for delivering a pre-specified medication to a body location comprising

a housing containing at least

a source of electrical current pulses;

microprocessor control means for automatically providing said current pulses in accordance with a fixed, predetermined program established in said microprocessor control means prior to manufacture of said system for controlling the level of said current pulses and the time period over which said pulses are to be provided;

means for retaining said pre-specified medication, being electrically charged, for placement at a body location for forming with said body location an electrical current path responsive to said current pulses to cause said medication to be delivered transdermally from said medication retaining means to said body location;

said microprocessor means thereby permitting a predetermined dosage of said pre-specified medication to be delivered automatically at a predetermined rate to said body location in accordance with said fixed, predetermined program wherein said medication retaining means is formed separately from said housing and includes a hydrophilic membrane having molecules of a medication distributed therein, and further including

electrode means for coupling to said separately formed medication retaining means;

cable means for interconnecting said electrode means and said source of current pulses,

one or more separately formed cartridges containing medication in liquid form, each cartridge being inserted into said housing means for attachment to said cable means, said cable means including a channel for transporting said liquid medication to the membrane of said medication retaining means for distribution of said medication therein.

2. A transdermal medication delivery system in accordance with claim 1 wherein said control means includes means for permitting a user of said system manually to start and/or stop the delivery of said medication to said body location.

3. A transdermal medication delivery system in accordance with claim 1 wherein said housing further contains at least one sensor means for sensing a selected body characteristic at said body location, said control means being responsive to the sensed body characteristic from said sensor means for controlling the starting and/or stopping of the delivery of said medication to said body location.

4. A transdermal medication delivery system in accordance with claim 1 wherein said source of current pulses is a lithium battery.

5. A transdermal medication delivery system in accordance with claim 1 wherein said cartridge contains a predetermined dosage of a specified medication.