Implantable piezoelectric pump system

• US 4,944,659 A
• Filed: 11/22/1988
• Issued: 07/31/1990
• Est. Priority Date: 01/27/1987
• Status: Expired due to Fees

• Current Assignee: Kabi Pharmacia AB
• Original Assignee: Kabivitrum AB
• Inventors: Labbe, Jean-Marie, Cox, Robert E. L., Damhuis, Eduard H. J.
• Primary Examiner(s): Smith, Leonard E.
• Assistant Examiner(s): Scheuermann, David W.
• Application Number:
  US07/282,131
• Time in Patent Office: 616 Days
• Field of Search: 417/322, 417/413, 310/26, 604/131, 604/151, 604/891.1
• US Class Current: 417/413.2
• CPC Class Codes: A61M 2205/0294 Piezoelectric materials
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

A dispensing device for use in an implantable drug delivery system for ambulatory patients comprises a pump in a drug reservoir and a piezoelectric disc element bonded to a diaphragm member forming one wall of a pump chamber and a battery and electrical circuits for cyclically applying electrical voltage to the piezoelectric member for inducing pumping movement in the diaphragm member to pump drugs from a reservoir via a valve and to a delivery catheter via another valve. A gas spring is provided to move the pump to maintain adequate pressure in the drug reservoir.

Claims

1. A dispensing device, comprising:

a housing forming a reservoir for fluid to be dispensed and a pump for dispensing the fluid located within the reservoir;

said pump including a pump chamber, a movable pump element and a piezoelectric element, said pump element being physically contiguous with and directly coupled to said piezoelectric element whereby changes in dimension of said piezoelectric element induce pumping movement in the movable pump element;

a source of electrical power connected to a control means for cyclically applying electrical voltage to said piezoelectric element for inducing periodic changes in dimension in said piezoelectric element;

a first one-way valve member bing directly connected between the fluid reservoir and the pump chamber for permitting flow of a fluid from said reservoir into said pump chamber upon movememt of the pump element and a second one-way valve member connected between the pump chamber and an outlet for dispensing said fluid from said pump chamber; and

means for maintaining the pressure of the fluid in the reservoir as the fluid is being dispensed, said pressure maintaining means including an expandable member having one end connected to said pump which closes a space defined by said expandable member.

2. A dispensing device according to claim 1, wherein said movable pump element comprises a flexible diaphragm forming a part of the wall of said pump chamber.

3. A dispensing device according to claim 1, wherein the source of electrical power is a battery in the shape of a disc and the control menas in the shape of a planar member, wherein the battery, control circuit and pump chamber are stacked upon one another to form a disc-like pump configuration.

4. A dispensing device according to claim 2, wherein the source of electrical power is a battery in the shape of a disc and the control means in the shape of a planar member, wherein the battery, control circuit and pump chamber are stacked upon one another to form a disc-like pump configuration.

5. A dispensing device according to claim 1, wherein said control means includes receiver means responsive to remotely transmitted electromagnetic waves for actuating said pump.

6. A dispensing device according to claim 2, wherein said control means includes receiver means responsive to remotely transmitted electromagnetic waves for actuating said pump.

7. A dispensing device according to claim 5, further comprising means for checking the condition of the source of electrical power.

8. A dispensing device according to claim 1, comprising an inlet chamber connected to said reservoir and sealed by an elastomeric member for permitting injection of the fluid into said reservoir by means of a hypodermic syringe.

9. A dispensing device according to claim 1, wherein said expandable member is a bellows.