Method of maximizing catheter longevity in an implantable medication infusion system
First Claim
1. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
- determining in a patient the level of at least one parameter from the group of parameters consisting of blood triglyceride level, blood cholesterol level, the level of insulin dosage per day, and mean blood glucose (MBG) level;
comparing the determined level of said at least one parameter with a predetermined maximum value for said at least one parameter to determine whether said at least one parameter is greater than said predetermined maximum value or not; and
providing an indication of increased risk of catheter blockage if said at least one parameter is greater than said predetermined maximum value.
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Abstract
A method of significantly enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate without encountering significant blockage by fibrotic tissue is disclosed. By monitoring and maintaining certain physical parameters in patients having an implantable catheter below desirable levels for the parameters, catheter survival in the patients is maximized. The four parameters used are blood triglyceride level, blood cholesterol level, the level of insulin dosage per day, and mean blood glucose (MBG) level, with the first two being the more accurate parameters.
136 Citations
21 Claims
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1. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining in a patient the level of at least one parameter from the group of parameters consisting of blood triglyceride level, blood cholesterol level, the level of insulin dosage per day, and mean blood glucose (MBG) level; comparing the determined level of said at least one parameter with a predetermined maximum value for said at least one parameter to determine whether said at least one parameter is greater than said predetermined maximum value or not; and providing an indication of increased risk of catheter blockage if said at least one parameter is greater than said predetermined maximum value. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining the level of triglycerides in the blood of a patient; comparing the determined level of triglycerides with a predetermined maximum value for triglycerides to determine whether the determined level of triglycerides is greater than said predetermined maximum value for triglycerides or not; providing an indication of increased risk of catheter blockage if the determined level of triglycerides is greater than said predetermined maximum value for triglycerides; determining the level of cholesterol in the blood of a patient; comparing the determined level of cholesterol with a predetermined maximum value for cholesterol to determine whether the determined level of cholesterol is greater than said predetermined maximum value for cholesterol or not; providing an indication of increased risk of catheter blockage if the determined level of cholesterol is greater than said predetermined maximum value for cholesterol; determining the level of insulin dosage per day of a patient; comparing the determined level of insulin dosage per day with a predetermined maximum value for insulin dosage per day to determine whether the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day or not; providing an indication of increased risk of catheter blockage if the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day; determining the level of mean blood glucose (MBG) in the blood of a patient; comparing the determined level of mean blood glucose with a predetermined maximum value for mean blood glucose to determine whether the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose or not; and providing an indication of increased risk of catheter blockage if the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose.
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17. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining the level of triglycerides in the blood of a patient; comparing the determined level of triglycerides with a predetermined maximum value for triglycerides to determine whether the determined level of triglycerides is greater than said predetermined maximum value for triglycerides or not; providing an indication of increased risk of catheter blockage if the determined level of triglycerides is greater than said predetermined maximum value for triglycerides; determining the level of cholesterol in the blood of a patient; comparing the determined level of cholesterol with a predetermined maximum value for cholesterol to determine whether the determined level of cholesterol is greater than said predetermined maximum value for cholesterol or not; and providing an indication of increased risk of catheter blockage if the determined level of cholesterol is greater than said predetermined maximum value for cholesterol.
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18. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining the level of triglycerides in the blood of a patient; comparing the determined level of triglycerides with a predetermined maximum value for triglycerides to determine whether the determined level of triglycerides is greater than said predetermined maximum value for triglycerides or not; and providing an indication of increased risk of catheter blockage if the determined level of triglycerides is greater than said predetermined maximum value for triglycerides.
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19. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining the level of cholesterol in the blood of a patient; comparing the determined level of cholesterol with a predetermined maximum value for cholesterol to determine whether the determined level of cholesterol is greater than said predetermined maximum value for cholesterol or not; and providing an indication of increased risk of catheter blockage if the determined level of cholesterol is greater than said predetermined maximum value for cholesterol.
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20. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining the level of insulin dosage per day of a patient; comparing the determined level of insulin dosage per day with a predetermined maximum value for insulin dosage per day to determine whether the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day or not; and providing an indication of increased risk of catheter blockage if the determined level of insulin dosage per day is greater than said predetermined maximum value for insulin dosage per day.
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21. A method of enhancing the period of time that an implanted intraperitoneal catheter used for the delivery of therapeutic medication will operate in a patient without encountering significant blockage, comprising:
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determining the level of mean blood glucose (MBG) in the blood of a patient; comparing the determined level of mean blood glucose with a predetermined maximum value for mean blood glucose to determine whether the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose or not; and providing an indication of increased risk of catheter blockage if the determined level of mean blood glucose is greater than said predetermined maximum value for mean blood glucose.
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Specification