Hand held glucose colorimeter device

• US 4,949,400 A
• Filed: 03/31/1988
• Issued: 08/14/1990
• Est. Priority Date: 03/31/1988
• Status: Expired due to Fees

• Current Assignee: Harry H. Leveen, Stephen D. Kahler, William F. Kahler
• Original Assignee: Harry H. Leveen, Stephen D. Kahler, William F. Kahler
• Inventors: Kahler, William F., Kahler, Stephen D., Leveen, Harry H.
• Primary Examiner(s): Evans, F. L.
• Application Number:
  US07/176,331
• Time in Patent Office: 866 Days
• Field of Search: 356/36, 356/38, 356/39, 356/402, 356/407, 356/409, 356/420, 356/425, 356/432, 356/436, 356/440, 356/446, 128/770, 128/630, 128/636, 364/413.07, 364/413.09, 364/413.11
• US Class Current: 356/420
• CPC Class Codes: G01N 21/255 Details, e.g. use of specially adapted sources, lighting or optical systems
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G01N 2201/0621 Supply

Abstract

A method and apparatus for increasing the sensitivity and accuracy of apparatus used in chemical analysis utilizing the colorimeter method. The method employs two or more light emitting diodes which emit light at different wavelengths. The emission wavelength of the L.E.D. is automatically switched to an L.E.D. which most closely matches any desired absorption band in the solution being analyzed so that more or less absorption will occur in each range. A logic circuit which utilizes the initial optical density to choose the proper L.E.D. for the particular range of concentration of chromophore. Thus, a green emitting diode may be used to register an initial color change and automatically switched to a red L.E.D. at any chosen concentration.

Claims

1. A process of operating a glucose monitoring system comprising the steps of

(a) selectively energizing one of a plurality of different color light emitting diodes to emit light against a test specimen strip with a glucose concentration falling within a range of differing glucose concentrations causing differing absorption spectra;

(b) receiving conductive emissions from a selected diode through said test specimen strip with photo transistor means and converting the emissions with said photo transistor means into an electronic signal;

(c) transmitting said electronic signal to a computer;

(d) providing said computer with a characteristic data base comprising a plurality of records corresponding to each of a number of readout components, each of said records comprising a plurality of characteristic identifiers describing corresponding specimens and including at least characteristics in the categories of milliliters per deciliter, four digit number readout, acceptability indicator; and

(e) displaying said characteristics.

2. The process as claimed in claim 1 wherein said characteristics which are displayed in step (e) are displayed by a printer.

3. The process as claimed in claim 1 wherein said characteristics which are displayed in step (e) are displayed by a speech synthesizer means.

4. The process as claimed in claim 1 wherein said characteristics which are displayed in step (e) are displayed by a CRT.

5. An apparatus for measuring chemical concentration on a media comprising;

a housing, means in said housing for receiving a test media strip having an unknown concentration of test sample, a plurality of different monochromatic light emitting diodes mounted in said housing and connected to a power source, said light emitting diodes being adapted to be selectively powered at a preselected test sample concentration to transmit light through said test media strip with concentration of test sample, photo transistor means mounted in said housing, said photo transistor means being adapted to receive light from a specifically selected light emitting diode selected from said plurality of light emitting diodes which passes through said test media strip with test sample and transmit current proportional to an amount of light being received to an analog-to-digital converter, said analog-to-digital converter producing a digital signal and being connected to computer means which receives the digital signal and transmits selected information about the test sample concentration on the test media strip.

6. An apparatus for measuring chemical concentration as claimed in claim 5 wherein said light emitting diodes are red and green and are selectively powered by a power source and said apparatus includes switching means which switches the power source from the red light emitting diode to the green emitting diode at a preselected sample concentration sensed by a decrease in the transmission of light.

7. An apparatus as claimed in claim 5 wherein said selected information is transmitted to measurement and read out means for converting the signal to a read out indicative of at least one of either the absorbence or transmission of said test media strip with sample with respect to the wavelength of said monochromatic light reflecting a color change in a chromogenic indicator on said test media strip.

8. An apparatus as claimed in claim 5 wherein said sample is glucose.