Device for administering solid preparations

• US 4,950,234 A
• Filed: 05/25/1988
• Issued: 08/21/1990
• Est. Priority Date: 05/26/1987
• Status: Expired due to Fees

• Current Assignee: Nissho Corporation (Nitto Denko Corporation), Sumitomo Pharmaceuticals Company Limited (Sumitomo Chemical Company Limited)
• Original Assignee: Nissho Corporation (Nitto Denko Corporation), Sumitomo Pharmaceuticals Company Limited (Sumitomo Chemical Company Limited)
• Inventors: Himeshima, Kenji, Tamura, Nobuhiko, Takada, Yoshihiro, Fujioka, Keiji
• Primary Examiner(s): Pellegrino, Stephen C.
• Assistant Examiner(s): DeFranco, Denise W.
• Application Number:
  US07/198,290
• Time in Patent Office: 818 Days
• Field of Search: 604/51, 604/57, 604/59, 604/60, 604/62, 604/218, 604/122, 604/283
• US Class Current: 604/60
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027

Abstract

A device for administering solid or semisolid preparations in an organism subcutaneously. The equipment comprises a barrel having a nozzle for attachment of a hollow needle, a plunger slidably arranged in the barrel and is used in combination with a guide member adapted to be snugly accommodated within the lumen of the barrel. The solid preparations are generally housed in the guide member and/or needle and forced into the body subcutaneously through the needle.

Claims

1. A device for subcutaneously administering a solid or semisolid preparation in an organism, which comprises a solid preparation injector and a guide member containing one or more solid preparations and being loaded with said injector,

said solid preparation injector comprising a needle member with a pointed end, a barrel having a nozzle for attachment of said needle member, and a plunger slidably arranged in said barrel, said barrel having a front and rear end and having a lumen tapered at said front end to provide a seat for said guide member, said plunger comprising a plunger body and an elongated small-sized rod portion being connected at one end to the tip of said plunger body, said small-sized rod portion having an outside diameter equal to or smaller than the inside diameter of said needle member with the length of said small-sized rod portion being determined such that said tip of said small-sized rod portion is stopped within said pointed end of said needle member when said plunger is forced into said barrel loaded with said guide member until said plunger stops, said guide member having an outside diameter slightly smaller than the inner diameter of said barrel and having a guide hole for guiding said small-sized rod portion in said lumen of said needle member, said solid preparations being contained in said guide hole of said guide member.

2. The device according to claim 1 wherein said needle is provided with an air hole for discharging air in the barrel and the needle.

3. The device according to claim 1 wherein said barrel is of a transparent synthetic resin.

4. The device according to claim 1 wherein the needle is a cylindrical hollow tube with no hub and has an outside diameter equal to the inside diameter of the nozzle of the barrel, and wherein the needle is being fixed in the nozzle of the barrel with adhesive.

5. The device according to claim 1 wherein the needle consists of a cylindrical hollow tube and a hub mounted on the base of the tube, said tube having an inside diameter equal to that of the nozzle of the barrel.

6. The device according to claim 1 wherein the guide member is tapered at its front part to fit within said seat.

7. The device according to claim 6 wherein the guide hole of the guide member is sealed by a cap removably mounted on the rear end of the guide member and a film of an biocompatible material fixed to the tip end of the guide member.

8. The device according to claim 1 wherein said guide hole of said guide member has an outside diameter slightly smaller than the inner diameter of said barrel, and wherein said guide hole includes a tapered guide way and an elongated straight hole extending from the small end of said tapered guide way to the tip of said guide member.

9. A device for subcutaneously administering a solid or semisolid preparation in an organism which comprises a hollow needle member, a barrel having a lumen and a nozzle for attachment of said needle member, a plunger slidably arranged in said barrel, and a guide member snugly accommodated within said lumen of said barrel and in contact with the front inner wall of said barrel,

said plunger comprising a plunger body having an outside diameter equal to or slightly smaller than the inside diameter of said barrel and an elongated small-sized rod portion having an outside diameter equal to or slightly smaller than the inside diameter of said needle, said smaller rod portion being connected to the tip of said plunger and having a length equal to or slightly smaller than a distance from the rear end of said guide member to the tip of said needle member,

said guide member having an outside diameter slightly smaller than the inside diameter of said barrel and being provided with a funnel-shaped guide hole to guide said small-sized rod portion of said plunger, said guide hole of said guide member containing at least one solid preparation.

10. A guide member for use in a device for subcutaneous implantation of a solid preparation comprising a hollow cylindrical barrel, a plunger slidably arranged in said barrel, and a hollow needle member attached to said barrel, said guide member comprising a cylindrical body with an outside diameter slightly smaller than the inner diameter of said barrel, and having a guide hole composed of a tapered guide portion having a small end and an elongated straight portion extending from the small end of said tapered portion to the tip of said guide member, and wherein said guide member is tapered at its front part to fit within the tapered front inner wall of the barrel, and wherein said guide hole of said guide member is sealed by a cap removably mounted on the rear end of said guide member and a film of a biocompatible material fixed to the tip end of said guide member.

11. The guide member according to claim 10 wherein said guide member contains at least one of said preparation in said guide hole.

12. A device for subcutaneously administering a solid or semisolid preparation in an organism, comprising a hollow needle member containing at least one solid preparation, a barrel having a lumen and a nozzle for attachment of said needle member, a plunger slidably arranged in said barrel, and a guide member snugly accommodated within said lumen of said barrel and to be in contact with the front inner wall of said barrel, said plunger comprising a plunger body having an outside diameter equal to or slightly smaller than the inside diameter of said barrel and an elongated small-sized rod portion having an outside diameter equal to or slightly smaller than the inside diameter of said needle, said small-sized rod portion being connected to the tip of the plunger body and having a length equal to or slightly smaller than a distance from the rear end of said guide member to the tip of said needle member.