Container-side occlusion detection system for a medication infusion system

• US 4,950,235 A
• Filed: 05/10/1988
• Issued: 08/21/1990
• Est. Priority Date: 05/10/1988
• Status: Expired due to Term

• Current Assignee: Cardinal Health 303 Incorporated (Cardinal Health, Inc.)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Hong, Son H., Henke, James L., Slate, John B.
• Primary Examiner(s): Yasko, John D.
• Assistant Examiner(s): Gutowski, Anthony
• Application Number:
  US07/192,280
• Time in Patent Office: 833 Days
• Field of Search: 417/45, 417/63, 417/44, 604/52, 604/65, 604/67, 604/121, 604/131, 604/151, 604/152, 604/245, 604/246, 128/DIG. 1, 128/DIG. 12, 128/DIG. 13
• US Class Current: 604/65
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/365 Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626
• CPC Class Codes: Y10S 128/13 Infusion monitoring

Abstract

A system for detecting an occlusion in a fluid line is disclosed which can detect occlusions in the upstream or container side of a disposable cassette containing a fluid pump therein. The cassette includes a piston-type pump with inlet and outlet valves, and is for installation onto and use with a main pump unit including motors for driving the pump and valves contained in each cassette. The system utilizes control circuitry to monitor the intake stroke of the pump in the cassette, to detect an upstream occlusion in the fluid line leading to the pump, and to provide an alarm in the event of a container-side occlusion.

Claims

1. A container-side occlusion detection system for use in a medication infusion system having a disposable cassette mounted onto a main pump unit, comprising:

a reciprocating piston pump located in a disposable cassette, said pump having a fill stroke and a deliver stroke;

a motor location in a main pump unit, said motor for driving said pump;

means for monitoring motor current during said fill stroke of said pump, said motor current being indicative of the presence or absence of a container-side occlusion in a fluid line, said monitoring means comprising an integrator for taking the first integral of motor current and providing as an output a CSOD value characteristic of said motor current;

means for providing an alarm; and

means for comparing said CSOD value to a preselected alarm threshold value, said comparing means causing said means for providing an alarm to initiate an alarm when said CSOD value exceeds said preselected alarm threshold value.

2. A container-side occlusion detection system as defined in claim 1, wherein said integrator integrates motor current during said fill stroke.

3. A container-side occlusion detection system as defined in claim 2, wherein said integrator also integrated motor current during a period following said fill stroke but prior to said deliver stroke.

4. A container-side occlusion detection system as defined in claim 1, wherein said integrator holds said CSOD value during said deliver stroke to allow said CSOD value to be sampled.

5. A container-side occlusion detection system as defined in claim 4, wherein said integrator is reset prior to the succeeding fill stroke.

6. A container-side occlusion detection system as defined in claim 1, wherein said monitoring means additionally comprises:

an analog-to-digital converter for converting said CSOD value into a digital signal.

7. A container-side occlusion detection system as defined in claim 1, wherein said monitoring means additionally comprises:

a shunt resistor in series with said motor, the input to said integrator being provided across said shunt resistor.

8. A container-side occlusion detection system as defined in claim 1, additionally comprising:

means for calibrating said system, said calibration means providing as an output said preselected alarm threshold value.

9. A container-side occlusion detection system as defined in claim 8, wherein said preselected threshold value is the measured CSOD value using a test cassette having no cassette friction multiplied by a constant factor between 1.5 and 3.0.

10. A container-side occlusion detection system as defined in claim 9, wherein said constant value is approximately 2.0.

11. A container-side occlusion detection system as defined in claim 9, wherein said calibration means provides minimum and maximum limits to said preselected threshold value.

12. A container-side occlusion detection system as defined in claim 11, wherein said minimum limit is 42 and said maximum limit is 80.

13. A container-side occlusion detection system as defined in claim 1, additionally comprising:

means for driving said motor, wherein said motor is driven by periodic pulses supplied by said driving means, said pulses being either at a lower commanded drive voltage or at a higher commanded drive voltage, said higher commanded drive voltage being used at higher flow rates.

14. A container-side occlusion detection system as defined in claim 13, wherein said lower commanded drive voltage supplied by said driving means is approximately 5 Volts and said higher commanded drive voltage supplied by said driving means is approximately 13 Volts.

15. A container-side occlusion detection system as defined in claim 13, wherein said CSOD value is monitored by said monitoring means following each fill stroke when said motor is being driven at said lower commanded drive voltage, and wherein when said motor is being driven at said higher commanded drive voltage said motor is periodically driven through an entire fill stroke at said lower commanded drive voltage to allow said CSOD value to be monitored.

16. A container-side occlusion detection system as defined in claim 13, wherein said CSOD value is monitored by said monitoring means once during each time a predetermined number of periodic pulses occurs when said motor is being driven at either said higher commanded drive voltage or said lower commanded drive voltage.

17. A container-side occlusion detection system as defined in claim 16, wherein said CSOD value is monitored by said monitoring means once during each five periodic pulses.

18. A container-side occlusion detection system as defined in claim 17, wherein in a start-up infusion said CSOD value is monitored by said monitoring means during the second periodic pulse.

19. A container-side occlusion detection system as defined in claim 16, wherein when said CSOD value is to be monitored by said monitoring means during a periodic pulse, the drive voltage supplied by said driving means is reduced to said lower commanded drive voltage until said pump is driven through one complete fill stroke, after which the drive voltage is returned to said higher commanded drive voltage, a periodic pulse including both said lower commanded drive voltage and said higher commanded drive voltage being referred to as a hybrid voltage pulse.

20. A container-side occlusion detection system as defined in claim 19, wherein the width of a hybrid voltage pulse supplied by said driving means is calculated according to the formula:

##EQU2## where N_p is the calculated position in the delivery cycle (between 0 and 160 encoder counts, where 0 is the beginning of the delivery cycle and 160 is the end), N_c is the command to the rate control expressed as encoder counts (i.e. converted from ml/h), U₁₃ is the pulse width calculated by the closed loop controller at the present sampling period, and g is the gain.

21. A container-side occlusion detection system for use in a medication infusion system having a disposable cassette mounted onto a main pump unit, comprising:

a reciprocating piston pump located in a disposable cassette, said pump having a fill stroke and a deliver stroke;

a motor located in a main pump unit, said motor for driving said pump;

means for monitoring motor current during said fill stroke of said pump, motor current being indicative of the presence or absence of a container-side occlusion in a fluid line, said monitoring means providing as an output a CSOD value characteristic of said motor current;

an integrator for taking the first integral of motor current to produce said CSOD value;

means for providing an alarm; and

means for comparing the output of said integrator to a preselected alarm threshold value, said comparing means causing said means for providing an alarm to initiate an alarm when said CSOD value exceeds said preselected alarm threshold value.

22. A container-side occlusion detection system for use in a medication infusion system comprising a disposable cassette including a reciprocating piston pump mounted onto a main pump unit including a motor for driving the pump, said container-side occlusion detection system comprising:

means for monitoring motor current during a fill stroke of said pump, said motor current being indicative of the present or absence of a container-side occlusion in a fluid line, said monitoring means comprising an integrator for taking the first integral of motor current and providing as an output a CSOD value characteristic of said motor current;

means for providing an alarm; and

means for comparing said CSOD value to a preselected alarm threshold value, said comparing means causing said means for providing an alarm to initiate an alarm when said CSOD value exceeds said preselected alarm threshold value.

23. A method of detecting a container-side occlusion in a medication infusion system having a disposable cassette mounted onto a main pump unit, comprising:

providing a reciprocating piston pump in said disposable cassette, said pump having a fill stroke and a deliver stroke;

driving said pump with a motor located in said main pump unit;

monitoring motor current during said fill stroke of said pump, said motor current being indicative of the presence or absence of a container-side occlusion in a fluid line, said monitoring means comprising an integrator for taking the first integral of motor current and providing as an output a CSOD value characteristic of said motor current; and

comparing said CSOD value to a preselected alarm threshold value, said comparing means initiating an alarm when said CSOD value exceeds said preselected alarm threshold value.