Desoxyribonucleic acid; microorganisms; diagnostic agent for delta infection and the use thereof
First Claim
Patent Images
1. The DNA having at least 60% homology relative to a portion of δ
- -RNA and being capable of selective hybridization with δ
-RNA.
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Abstract
This invention relates to DNA having at least 60% homology relative to γ-RNA or a portion thereof and the capacity of selective hybridization with δ-RNA. Such DNA, if provided with a detectable label, such as 32 P can be used as a diagnostic agent to diagnose δ infection.
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Citations
9 Claims
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1. The DNA having at least 60% homology relative to a portion of δ
- -RNA and being capable of selective hybridization with δ
-RNA. - View Dependent Claims (2, 3, 4, 5, 6, 8)
- -RNA and being capable of selective hybridization with δ
- 7. A DNA selected from the group consisting of DNA having the following base sequence
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10 20 30 CCCCGTTGCT TTCTTTACTT TCCTCCTCGC GGGGCAACGA AAGAAATGAA AGGAGGAGCG 40 50 60 TTCGGTCTCC CCCTACTCCT AGCATCTCCT AAGCCAGAGG GGGATGAGGA TCGTAGAGGA 70 80 90 CCTATCGCTA TGGTCTTACT CCTACCGCTC GGATAGCGAT ACCAGAATGA GGATGGCGAG 100 110 120 GAAGCGCCTC TTGTTCGCTG AAGGGGTCCT CTTCGCGGAG AACAAGCGAC TTCCCCAGGA 130 140 150 CTGGAGGTGA TTTCTCTGCT CATCTCCGAG GACCTCCACT AAAGAGACGA GTAGAGGCTC 160 170 180 TGGATTCCTC CCTCTGGGTG CTACTCAACC ACCTAAGGAG GGAGACCCAC GATGAGTTGG 190 200 210 CTTCGGGCCG GAGTGCTCTC CAGATCTGGA GAAGCCCGGC CTCACGAGAG GTCTAGACCT 220 230 240 GGTTGGGCCC CTCGGATCGG GAGGCCCGCT CCAACCCGGG GAGCCTAGCC CTCCGGGCGA 250 260 270 CCTTTTTCTT CCACCTTCCT CTTTCCCCTT GGAAAAAGAA GGTGGAAGGA GAAAGGGGAA 280 290 300 CCAGAGATTC TCCGGCGTTG TGGGGATCTC GGTCTCTAAG AGGCCGCAAC ACCCCTATAG 310 320 330 GTCCGCTTCC TGAGACCTCT CTTTGCTTCT CAGGCGAAGG ACTCTGGAGA GAAACGAAGA 340 350 360 TGGGAGTAGT TTCTCCGACG TTCCAATGCT ACCCTCATCA AAGAGGCTGC AAGGTTACGA 370 380 390 CTTTACCGTG ACATCCCCTC TCGGGAGCTG GAAATGGCAC TGTAGGGGAG AGCCCTCGAC A T ←
5'"'"', ______________________________________
a DNA homologous therewith as to at least 60%, or a portion thereof, and capable of selective hybridization with δ
-RNA. - space="preserve" listing-type="tabular">______________________________________ 5'"'"' →
- 9. Recombinant DNA selected from the group consisting of DNA having the following base sequence
- space="preserve" listing-type="tabular">______________________________________ 5'"'"' →
10 20 30 CCCCGTTGCT TTCTTTACTT TCCTCCTCGC GGGGCAACGA AAGAAATGAA AGGAGGAGCG 40 50 60 TTCGGTCTCC CCCTACTCCT AGCATCTCCT AAGCCAGAGG GGGATGAGGA TCGTAGAGGA 70 80 90 CCTATCGCTA TGGTCTTACT CCTACCGCTC GGATAGCGAT ACCAGAATGA GGATGGCGAG 100 110 120 GAAGCGCCTC TTGTTCGCTG AAGGGGTCCT CTTCGCGGAG AACAAGCGAC TTCCCCAGGA 130 140 150 CTGGAGGTGA TTTCTCTGCT CATCTCCGAG GACCTCCACT AAAGAGACGA GTAGAGGCTC 160 170 180 TGGATTCCTC CCTCTGGGTG CTACTCAACC ACCTAAGGAG GGAGACCCAC GATGAGTTGG 190 200 210 CTTCGGGCCG GAGTGCTCTC CAGATCTGGA GAAGCCCGGC CTCACGAGAG GTCTAGACCT 220 230 240 GGTTGGGCCC CTCGGATCGG GAGGCCCGCT CCAACCCGGG GAGCCTAGCC CTCCGGGCGA 250 260 270 CCTTTTTCTT CCACCTTCCT CTTTCCCCTT GGAAAAAGAA GGTGGAAGGA GAAAGGGGAA 280 290 300 CCAGAGATTC TCCGGCGTTG TGGGGATCTC GGTCTCTAAG AGGCCGCAAC ACCCCTATAG 310 320 330 GTCCGCTTCC TGAGACCTCT CTTTGCTTCT CAGGCGAAGG ACTCTGGAGA GAAACGAAGA 340 350 360 TGGGAGTAGT TTCTCCGACG TTCCAATGCT ACCCTCATCA AAGAGGCTGC AAGGTTACGA 370 380 390 CTTTACCGTG ACATCCCCTC TCGGGAGCTG GAAATGGCAC TGTAGGGGAG AGCCCTCGAC A T ←
5'"'"', ______________________________________
a DNA homologous therewith as to at least 60%, or a portion thereof, and capable of selective hybridization with δ
-RNA. - space="preserve" listing-type="tabular">______________________________________ 5'"'"' →
Specification