Blood coagulation time measuring device

• US 4,964,728 A
• Filed: 03/01/1989
• Issued: 10/23/1990
• Est. Priority Date: 03/11/1977
• Status: Expired due to Term

• Current Assignee: LAbor BioMedical Technologies GmbH (HUMAN Gesellschaft für Biochemica und Diagnostica mbH)
• Original Assignee: Labor Laborgerate + Analysensysteme Vertriebsgesellschaft Mbh
• Inventors: Kloth, Bernd, Behnk, Holger
• Primary Examiner(s): ARNOLD, BRUCE
• Application Number:
  US07/317,123
• Time in Patent Office: 601 Days
• Field of Search: 250/238, 250/239, 250/576, 356/39, 356/73, 356/426, 356/427, 356/432, 356/436-438, 356/441, 356/442, 422/73
• US Class Current: 356/427
• CPC Class Codes: B01F 2101/23 Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
• CPC Class Codes: B01F 33/452 using independent floating stirring elements
• CPC Class Codes: B01F 35/2136 Viscosity
• CPC Class Codes: G01N 33/4905 Determining clotting time of blood by chemical methods G01N33/86, C12Q1/56

Abstract

A blood coagulation time measuring device includes a stirrer drive arrangnt for rotating a stirring rod placed inside the measuring vessel when the vessel is inserted in a measuring channel of the device. A light detector assembly within the device determines the degree of coagulation formation in the measuring vessel by transmitting a light beam from a light source through the measuring vessel and onto a photo-electric cell. Light balancing circuitry coupled to the light source and the photo-electric cell automatically adjusts the brightness of the light from the light source in correspondence with the turbidity of liquid in the measuring vessel. A control switch arrangement operates to turn the stirrer drive arrangement on or off in response to operation of the light balancing circuitry.

Claims

1. A blood coagulation time measuring device, comprising a container, channel means extending into said container for forming a measuring channel for supporting a measuring vessel within said container, stirrer drive means in the region of said channel means for rotating a stirring rod placed inside the measuring vessel, a light detector assembly in said container including a light source and a photo-electric cell for determining the degree of coagulum formation in the measuring vessel wherein a light beam is transmitted from said light source through the measuring vessel in said measuring channel and onto said photo-electric cell which produces a corresponding output, light balancing means coupled to said light source and said photo-electric cell for adjusting the brightness of the light beam from said light source in corresponding relationship to the level of light received by said photo-electric cell wherein said brightness corresponds to the turbidity of liquid in the measuring vessel, display means for indicating blood coagulation time, and control switch means coupled to said light balancing means for controlling said stirrer drive means and said display means in response to operation of said light balancing means.

2. A blood coagulation time measuring device according to claim 1, wherein said light balancing means is arranged so that first and second threshold values corresponding to different liquid turbidity levels can be set wherein said stirrer drive means operates when the turbidity of liquid in the vessel exceeds said first threshold value and is less than said second threshold value, and said stirrer drive means ceases to operate when the liquid turbidity exceeds said second threshold value.

3. A blood coagulation time measuring device according to claim 1, including a timing device associated with said stirrer drive means for reducing the speed of rotation of the stirring rod in the measuring vessel at a certain time after said stirrer drive means is activated by said control switch means.

4. A blood coagulation time measuring device according to claim 1, wherein said light balancing means includes an amplifier.

5. A blood coagulation time measuring device according to claim 1, wherein said light source comprises an electric lamp arranged to provide full brightness at a certain operating voltage, and said light balancing means is arranged to apply about 30% of said operating voltage to said lamp when the measuring vessel in said measuring channel is empty.

6. A blood coagulation time measuring device according to claim 1, wherein said light source comprises an electric lamp, said light balancing means operates to vary the voltage applied to said lamp over a certain range in accordance with the output of said photo-electric cell, and said control switch means is arranged to operate when the voltage applied to said lamp is between predetermined limits within said certain range of voltage.