Catalytic test composition intended to produce a range of colors

• US 4,975,367 A
• Filed: 07/30/1987
• Issued: 12/04/1990
• Est. Priority Date: 04/04/1986
• Status: Expired due to Fees

• Current Assignee: Miles, Inc. (Bayer AG)
• Original Assignee: Miles, Inc. (Bayer AG)
• Inventors: Reinsch, James W., Charlton, Steven C., Albarella, James P., Warchal, Mary E.
• Primary Examiner(s): Rosen, Sam
• Assistant Examiner(s): Saunders, David A.
• Application Number:
  US07/079,692
• Time in Patent Office: 1,223 Days
• Field of Search: 422/55-57, 435/14, 435/25, 435/26, 435/805, 435/11, 436/904
• US Class Current: 435/11
• CPC Class Codes: C12Q 1/00 Measuring or testing processes involving enzymes, nucleic acids or microorganisms measuring or testing apparatus with condition measuring or sensing means, e.g. colony counters, C12M1/34; Compositions therefor; Processes of preparing such compositions
• CPC Class Codes: C12Q 1/26 involving oxidoreductase
• CPC Class Codes: C12Q 1/54 involving glucose or galactose
• CPC Class Codes: G01N 33/526 the element being adapted for a specific analyte
• CPC Class Codes: Y10S 435/805 Test papers
• CPC Class Codes: Y10S 436/904 Oxidation - reduction indicators

Abstract

Test compositions, indicators, and test device are provided which are capable of generating different hues at different analyte concentrations. The compositions are capable of generating a yellow hue in situ. Visual tests for clinically important analytes, such as glucose, are determined by use of two independent catalytic systems which are reactive with reduced nicotinamide adenine dinucleotide to produce a range of hues; the particular hue produced depending on the concentration of the analyte. The invention provides a test device for the determination of analyte, e.g. glucose, in body fluid which exhibits a rainbow of hues, the particular final hue produced depending on the analyte concentration.

Claims