Apparatus for in situ radiotherapy

• US 4,976,680 A
• Filed: 10/07/1988
• Issued: 12/11/1990
• Est. Priority Date: 10/07/1988
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Lee R. Morgan, Michael H. Hayman, Samuel F. Liprie
• Inventors: Hayman, Michael H., Liprie, Samuel F., Morgan, Lee R.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/255,045
• Time in Patent Office: 795 Days
• Field of Search: 600/1-8, 600/32, 128/897-899, 128/785, 128/334, 604/19, 604/21, 604/27, 604/93, 604/158, 604/171-172, 604/174-175, 604/280, 604/283
• US Class Current: 600/7
• CPC Class Codes: A61N 2005/1012 Templates or grids for guiding the introduction of sources
• CPC Class Codes: A61N 5/1027 Interstitial radiation therapy

Abstract

Apparatus for in situ radiotherapy has a flexible catheter having a proximal end for receiving a radiosotope and a distal end for positioning the flexible catheter within a patient to be treated. An anchor, which is permanently connectable to tissues deep inside the patient, has a sealing collar connected to it which seals the distal end of the catheter. The anchor has a penetration point connected to it to assist a surgeon in implanting the catheter within a tumor. A threaded fastener is connected to the anchor and screwed into the catheter. The flexible catheter can be released remotely from the anchor by unscrewing it. A suture eye is connected to the anchor. The suture eye may be sutured to healthy tissue within the patient when the apparatus is implanted to secure the anchor to the patient.

Claims

1. Apparatus for in situ radiotherapy of a patient, comprising:

a flexible guide tube having a proximal end for receiving a radioisotope and a distal end for positioning the guide tube within a patient to be treated;

an anchor;

sealing means for sealing the distal end of the guide tube;

anchor connector means for releasably connecting the anchor to the flexible guide tube; and

patient connection means connected to the anchor for connecting the anchor permanently to the patient.

2. Apparatus according to claim 1 wherein said sealing means is integral with said anchor.

3. Apparatus according to claim 1, wherein the flexible guide tube comprises a catheter.

4. Apparatus according to claim 1, wherein the connector means comprises a screw thread affixed to the anchor which engages the guide tube.

5. Apparatus according to claim 1, further comprising a bushing for engagement with a body wall of the patient and through which the flexible, guide tube extends.

6. Apparatus according to claim 5, further comprising a cuff engaging the bushing and adapted to promote growth of tissues in the body wall into proximity with the bushing.

7. Apparatus according to claim 1, wherein the patient connection means comprises an aperture in the anchor adapted to receive a suture for connection by the suture to a region of tissue internal to the patient and proximal to an area of the patient to be treated.

8. An apparatus according to claim 1, wherein the patient connection means comprises a slotted head portion on the anchor adapted to receive a vascular clip in engagement therewith.

9. Apparatus according to claim 1, further comprising penetration means connected to the anchor for penetrating a portion of the patient,s body to be treated.

10. Apparatus according to claim 9 wherein said penetration means comprises a sharp point integral with said anchor.

11. Apparatus for in situ radiotherapy of a patient, comprising:

a bushing, adapted for engagement with a body wall of the patient;

a plurality of catheters extending through the bushing, each catheter of said plurality having a proximal end including means for receiving a radioisotope and a distal end for positioning the catheter within a patient to be treated; and

sealing means connected to each of the distal ends of the catheters for sealing the distal ends of the catheters.

12. Apparatus according to claim 11, further comprising a cuff connected to the bushing for promoting tissue growth from the body wall of the patient into engagement with the bushing.