Supersonic hyperthermia treating method

• US 4,977,902 A
• Filed: 05/08/1989
• Issued: 12/18/1990
• Est. Priority Date: 07/15/1988
• Status: Expired due to Term

• Current Assignee: Olympus Optical Corporation Limited (Olympus Corporation)
• Original Assignee: Olympus Optical Corporation Limited (Olympus Corporation)
• Inventors: Takayama, Shuichi, Uchiyama, Naoki, Hayashi, Masaaki, Gotanda, Masakazu, Murata, Akira, Kami, Kuniaki, Sekino, Naomi, Kubota, Tetsumaru, Tsukaya, Takashi, Ishihara, Koichiro
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US07/348,814
• Time in Patent Office: 589 Days
• Field of Search: 128/399, 128/400, 128/422, 128/804, 128/24 AA, 600/12, 600/13
• US Class Current: 601/3
• CPC Class Codes: A61F 2210/0052 ultrasonically
• CPC Class Codes: A61F 7/123 using a flexible balloon containing the thermal element
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A supersonic hyperthermia treating method comprises the steps of inserting a heat generating member having a high attenuation for supersonic waves into a diseased part in a body and leaving it there, then transmitting supersonic waves generated outside of the body from a supersonic wave generator for heating the heat generating member to hyperthermically treat the diseased part.

Claims

1. A supersonic hyperthermia treating method comprising the steps of;

inserting a heat generating member having a high attenuation for supersonic waves into a part to be treated in a body;

leaving the heat generating member in the part; and

transmitting supersonic waves from the outside of the body to the heat generating member by means of a supersonic wave generator which generates supersonic waves to cause the heat generating member to heat the part to be treated.

2. A supersonic hyperthermia treating method as defined in claim 1 in which the supersonic wave generator is adapted to focus the generated supersonic waves on the heat generating member.

3. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is formed of a polymeric material of silicon rubber, polyethylene, acrylic resins, or ethylene tetrafluoride.

4. A supersonic hyperthermia treating method as defined in claim 3 for treating a part of an intra-abdominal organ in which the heat generating member made of a polymeric material is shaped according to the organ into which the member is to be inserted and the dimension and position of the part to be treated.

5. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member comprises a balloon made of an extensible elastomeric material.

6. A supersonic hyperthermia treating method as defined in claim 5 in which the extensible elastomeric material is latex or silicon rubber.

7. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is formed of a gel material.

8. A supersonic hyperthermia treating method as defined in claim 7 in which the gel material is a silicon gel.

9. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member has means for detecting a shift in position of the member from the part to be treated.

10. A supersonic hyperthermia treating method as defined in claim 9 in which the means comprises a layer of material having an acoustic impedance largely different from that of the heat generating member.

11. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is formed of a shape memory member, the shape of which changes with a change in temperature so that the temperature of the heat generating member is readable by detecting the change in shape from the outside of the body.

12. A supersonic hyperthermia treating method as defined in claim 11 in which the shape memory member is formed of a shape memory polymer.

13. A supersonic hyperthermia treating method as defined in claim 12 in which the polymer is a polystyrene resin or a polyurethane resin.

14. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member comprises a plurality of connected shape memory members having reacting temperatures different from each other so that the temperature of the heat generating member is readable from the member deformed.

15. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is detachably mounted to the tip end of a body cavity insertion portion of an endoscope, and is inserted into the part to be treated using said endoscope and is then detached from said tip end to leave the heat generating member in such part.

16. A supersonic hyperthermia treating method as defined in claim 15 in which the endoscope has a treating device insertion channel and means inserted in such channel which prevents the heat generating member from detaching and allows the heat generating member to detach by rotating the same.

17. A supersonic hyperthermia treating method as defined in claim 13 in which the preventing means comprises a balloon catheter inserted into the treating device insertion channel at the tip of the endoscope and which is inflated to prevent the heat generating member from detaching and which is deflated to detach the heat generating member.

18. A supersonic hyperthermia treating method as defined in claim 16 in which the preventing means comprises a gripping forceps inserted into the treating device insertion channel and which prevents the heat generating member from detaching by gripping a part of the heat generating member and allows the heat generating member to detach by opening the forceps.

19. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is made of a contracted shape memory member and is mounted on the outer periphery of the tip end of a body cavity insertion portion of an endoscope so that the heat generating member will not normally detach therefrom and so that the heat generating member may be detached by causing warm water to flow through said insertion portion to expand the heat generating member.

20. A supersonic hyperthermia treating method as defined in claim 19 in which the endoscope is a rigidscope.

21. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member comprises a heat generating liquid having a high viscosity which is introduced into a balloon of a balloon type catheter to inflate the balloon which is then inserted into and left at the part to be treated.

22. A supersonic hyperthermia treating method as defined in claim 21 in which the heat generating liquid is castor oil or glycerin.

23. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is made of a heat generating liquid having a high viscosity, the heat generating liquid being inserted into and disposed at the part to be treated through a catheter between both balloons of a double balloon type catheter inserted into the body cavity.

24. A supersonic hyperthermia treating method as defined in claim 23 in which the heat generating liquid is castor oil or glycerin.

25. A supersonic hyperthermia treating method as defined in claim 1 for treating a part of a body cavity in which a guide wire is inserted into the body cavity through a medical instrument and the wire is used as a guide to insert into and leave the heat generating member at the part to be treated.

26. A supersonic hyperthermia treating method as defined in claim 1 in which the heat generating member is made of a contracted shape memory member and is mounted on the outer periphery of the tip end of a catheter so that the heat generating member will not normally detach therefrom and so that the heat generating member may be detached by causing warm water to flow through said catheter to expand the heat generating member.

27. A supersonic treating method as defined in claim 1 further comprising measuring the temperature of the heat generating member using a temperature sensor, generating an electrical control signal representative of the difference between the measured temperature and a preset temperature and using the control signal to control the output of a supersonic oscillator driving circuit used to control the power supplied to the supersonic wave generator to thereby set the temperature of the heat generating member to the preset temperature.

28. A supersonic treatment method as defined in claim 27 in which the control signal is used to control the output voltage of the driving circuit.

29. A supersonic treatment method as defined in claim 27 in which the control signal is used to control the duty cycle of the driving circuit.