Biological syringe system

• US 4,978,336 A
• Filed: 10/03/1989
• Issued: 12/18/1990
• Est. Priority Date: 09/29/1987
• Status: Expired

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc., Cookston H. Stephen
• Original Assignee: Hemaedics, Inc.
• Inventors: Cookston, H. Stephen, Capozzi, Emil E.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Polutta, Mark O.
• Application Number:
  US07/418,707
• Time in Patent Office: 441 Days
• Field of Search: 604/94, 604/191, 604/283, 604/82, 604/85, 604/905, 604/240, 604/242, 604/243, 239/398, 239/432, 600/4, 600/5, 222/137, 222/129, 222/145
• US Class Current: 604/82
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: B05C 17/00516 Shape or geometry of the outlet orifice or the outlet element
• CPC Class Codes: B05C 17/0052 Accessories therefor
• CPC Class Codes: B05C 17/00593 Hand tools of the syringe type

Abstract

Syringe holder carriers first and second syringes which contain proteins which, when mixed, become a tissue adhesive. A manifold locks onto the two syringes, receives the two streams and delivers them to an output nose. A standard needle detachably locks onto the nose of the manifold. Alternatively to a needle, a spray nozzle can be locked thereon.

Claims

1. A biological syringe system for delivering a first and second fluid in a mixed composition said biological syringe system including a first and second syringe for holding said first and second fluids, and a corresponding first and second plunger for forcing said first and second fluids from said first and second syringes respectively, comprising:

a manifold, said manifold having first and second corresponding component channels therethrough, and first and second input connections respectively communicating with said first and second component channels, said first and second component channels terminating in corresponding exit channels adjacent to each other on an opposing end of said manifold;

a discharge assembly coupled to said opposing end of said manifold and receiving fluid from both of said exit channels, said discharge assembly for mixing fluid from both of said exit channels and delivering said mixed fluid in a spray, said discharge assembly having a first and second passage therethrough communicating with said exit channels from said manifold for carrying fluid from said first and second component channels in corresponding first and second passages within said discharge assembly while maintaining said first and second fluids separated from each other, said discharge assembly having a mixing space defined therein to receive separate flows from said passages, said discharge assembly further comprising mixing means disposed within said mixing space to thoroughly mix said first and second fluids for the first time within said mixing space and to immediately thereafter atomize said thoroughly mixed first and second fluids in a spray discharged from said discharge assembly.

2. The biological syringe system of claim 1 wherein said means for thoroughly mixing and atomizing said first and second fluid into a spray comprises a shaped spray nozzle having a spray outlet defined therein, said shaped spray nozzle being disposed within said mixing space.

3. The biological syringe system of claim 2 wherein said first and second passages have outlet ends, and wherein said discharge assembly comprises a solid cylindrical body disposed within said mixing space, said solid cylindrical body having a first end surface adjacent outlet ends of said first and second passage in said discharge assembly, said first and second fluids exiting said outlet ends of said passages and flowing into a cylindrical annular space between said nozzle disposed in said mixing space and said cylindrical body disposed in said mixing space, said first and second fluids mixing for the first time within said cylindrical annular space and flowing to a portion of said mixing space adjacent an opposing end of said solid cylindrical body opposite said spray outlet, said mixed first and second fluids then being expressed through said spray outlet as atomized spray particles.

4. A method for applying a tissue adhesive and protective covering which chemically forms and hardens as applied comprising the steps of:

providing a first fluid;

providing a second fluid which when mixed with said first fluid hardens into said tissue adhesive;

forcing said first and second fluids from a corresponding first and second syringe into corresponding first and second passages;

partially mixing said first and second fluids together by flowing said fluids under pressure within a cylindrical annular space; and

forcing said partially mixed first and second fluids from said cylindrical annular space into a final mixing chamber;

thoroughly mixing said first and second fluids in said final mixing chamber;

forcing said thoroughly mixed fluids to an axial spray orifice;

atomizing said thoroughly mixed first and second fluids by pressured ejection of said fluids through said spray orifice at a predetermined minimum pressure,

whereby mixture of said first and second fluids is substantially improved, strength and hardening of said tissue adhesive substantially improved, and wherein thorough mixing occurs just prior to application in atomized form.