Immunoassay or diagnostic device and method of manufacture
First Claim
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1. A hand held assay device comprising:
- a housing means,a movable transport means within the housing means,at least one liquid container within said housing means,said container comprising a molded, flexible blister having an open side,closure means spanning said open side to close and seal said blister,punch means molded integrally with said blister defining with said blister a single, unitary, seamless piece part,said punch means defining a cone having a base, a lateral surface and an apex,the lateral surface of said cone being interrupted by a plurality of grooves of varying depth extending from said base to said apex,the depth of said grooves being greatest at the base of said cone graduating to zero depth at the apex, andsaid cone being operable in response to deformation of the blister to rupture the closure means whereby said cone, by virtue of said grooves, is operable to release liquid from said container in a predictable manner.
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Abstract
Liquid containers or receptacles are disclosed with cooperating means for rupturing the receptacles to release contained fluid to rain upon test specimens. Structure is disclosed for rupturing receptacles in response to relative motion occurring between receptacles and test specimen support members or in response to punch means formed integrally with a receptacle. A method of molding a liquid receptacle with an integrally formed punch means for rupturing the receptacle is also disclosed.
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Citations
4 Claims
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1. A hand held assay device comprising:
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a housing means, a movable transport means within the housing means, at least one liquid container within said housing means, said container comprising a molded, flexible blister having an open side, closure means spanning said open side to close and seal said blister, punch means molded integrally with said blister defining with said blister a single, unitary, seamless piece part, said punch means defining a cone having a base, a lateral surface and an apex, the lateral surface of said cone being interrupted by a plurality of grooves of varying depth extending from said base to said apex, the depth of said grooves being greatest at the base of said cone graduating to zero depth at the apex, and said cone being operable in response to deformation of the blister to rupture the closure means whereby said cone, by virtue of said grooves, is operable to release liquid from said container in a predictable manner. - View Dependent Claims (2, 3)
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4. A liquid container for use in an assay or diagnostic device comprising:
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a molded, flexible blister having an open side, closure means spanning said open side to close and seal said blister, a punch means molded integrally with said blister defining with said blister a single, unitary, seamless piece part, said punch means defining a cone having a base, a lateral surface and an apex, the lateral surface of said cone being interrupted by a plurality of grooves of varying depth extending from said base to said apex, the depth of said grooves being greatest at the base of said cone graduating to zero depth at the apex, said cone being operable in response to deformation of the blister to rupture the closure means whereby said cone, by virtue of said grooves, is operable to release liquid from said container in a predictable manner.
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Specification