Specimen test unit

• US 4,978,504 A
• Filed: 02/09/1988
• Issued: 12/18/1990
• Est. Priority Date: 02/09/1988
• Status: Expired due to Term

• Current Assignee: Frederic L. Nason
• Original Assignee: Frederic L. Nason
• Inventors: Nason, Frederic L.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Trautman, Kimberly A.
• Application Number:
  US07/153,951
• Time in Patent Office: 1,043 Days
• Field of Search: 422/56, 422/57, 422/58, 422/61, 422/101, 422/102, 435/25, 435/295, 435/296, 435/810, 128/2, 128/759
• US Class Current: 422/411
• CPC Class Codes: A61B 10/0096 Casings for storing test samples A61B10/0038 and A61B10/0045 take precedence; preservation of living parts of the human or animal body A01N1/02; containers for retaining a material to be analysed B01L3/50; containers for enzymology or microbiology C12M1/16; swab-sampler being part of enzymology or microbiology container C12M1/30
• CPC Class Codes: A61B 10/02 Instruments for taking cell samples or for biopsy A61B10/0038 and A61B10/0045 take precedence; needle locating or guiding means A61B17/3403; samplers for enzymology or microbiology C12M1/26; sampling or preparing biological specimens G01N33/48
• CPC Class Codes: A61B 2010/0216 Sampling brushes
• CPC Class Codes: A61F 13/38 Swabs having a stick-type handle, e.g. cotton tips ear cleaners other than cotton tips A61F11/006; swabs containing a liquid, e.g. in a rupturable reservoir, A61M35/006
• CPC Class Codes: B01L 3/502 with fluid transport, e.g. in multi-compartment structures centrifugal-type cuvettes G01N21/07; analysis by separation into components G01N30/00; automatic analysers G01N35/00
• CPC Class Codes: B01L 3/5029 using swabs
• CPC Class Codes: G01N 2001/028 Sampling from a surface, swabbing, vaporising
• CPC Class Codes: Y10S 435/81 Packaged device or kit

Abstract

An improved test unit is provided for use in the collection and analysis of biological specimens and the like. The specimen test unit includes a swab member adapted for collection of a specimen to be tested. The test unit incorporates one or more reagents or other test fluids for delivery into contact with the specimens on the swab member. In accordance with various embodiments, the contacted specimen and fluid are then delivered through one or more porous filter members for analysis and/or to contact an additional reagent or reagents in the course of performing a selected test. In some forms, one or more of the porous filter members in preimpregnated with a selected reagent or constituent thereof. Moreover, in some forms, one or more of the porous filter members is formed from a hydrophobic material to serve as a fluid seal until fluid is forced therethrough, for example, by squeezing a reagent-containing housing member of the test unit. In all embodiments, the test unit is substantially self-contained to perform the desired test, with minimal risk of exposing testing personnel to the collected specimen and/or to the various reagents.

Claims

1. A specimen test unit for use in collection and analysis of a biological specimen or the like, said test unit comprising:

a housing member having an outlet opening;

at least one test fluid within said housing member.

collecting means carried by said housing member collecting the specimen, said housing member including means for delivering a test fluid into direct contact with the specimen on said collecting means; and

a cap having an open end for mounting onto said housing member with said cap substantially enclosing said collecting means, said cap further having a second end with an outlet port therein, and at least one porous filter member disposed across and substantially closing said outlet port, at least one of said housing member and said cap being squeezable while said cap is mounted on said housing member to force the specimen and the test fluid from said collecting means through said at least one filter member.

2. The specimen test unit of claim 1 wherein said at least one filter member includes a rounded nose projecting outwardly from said cap second end.

3. The specimen test unit of claim 1 wherein said at least one filter member includes at least two filter members disposed for series passage of the specimen and test fluid, said filter members carrying different reagents.

4. The specimen test unit of claim 1 wherein said at least one filter member has a reagent pre-impregnated therein.

5. The specimen test unit of claim 1 wherein said collecting means comprises a swab member, and means for supporting said swab member with respect to said housing member, said test fluid within said housing member being carried within a frangible ampoule and said housing member comprising a sufficiently deformable housing member material which permits said housing member to be deformed for rupturing said ampoule to release said test fluid and for squeezing said housing member to express the test fluid through said swab member support means and said delivery means to said swab member, said support means including a filter element for separating said test fluid from said ampoule.

6. The specimen test unit of claim 5, wherein said filter element is pre-impregnated with a selected reagent.

7. The specimen test unit of claim 1 further including a dropper unit for mounting onto said second end of said cap, said dropper unit including means for forming drops upon expression of fluids therefrom.

8. The specimen test unit of claim 7 wherein said drop forming unit further comprises porous filter member.

9. The specimen test unit of claim 7 further including a reagent within said dropper unit.

10. The specimen test unit of claim 1 further including a glass vial for mounting at said second end of said cap to receive filtered specimen from said cap, and a protective outer end cap engageable with said cap in overlying relation with said glass vial.

11. A specimen test unit for use in collection and analysis of a biological specimen or the like, said test unit comprising:

a housing having an outlet opening;

at least one test agent within said housing;

collecting means for collecting a specimen;

a cap having an open end for mounting onto said housing and cooperating with said housing to define a specimen chamber having a size and shape for receiving and substantially enclosing said collecting means with the specimen collected thereon, said cap further having a second end with an outlet port therein, and at least one porous filter member disposed across and substantially closing said outlet port, said housing including means for delivering the test agent to said specimen chamber for contacting the specimen placed therein; and

at least one of said housing and said cap being squeezable while said cap is mounted on said housing to force the test agent to contact the specimen to a force at least a portion of the specimen and the test agent from said specimen chamber through said at least one porous filter member.