Method employing gonadal hormones and dopamine agonist intended for combined use in the improvement of lymphocyte function
First Claim
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1. A pharmaceutical composition useful in enhancing stimulated lymphocyte function comprising a dopamine agonist selected from the group consisting of bromoncriptine, lergotrile and pergolide or pharmaceutically acceptable salts thereof and a gonadal hormone selected from the group consisting of progestinic, androgenic or estrogenic hormones, in therapeutically effective amounts.
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Abstract
A new method, useful as a pharmacologic strategy, contains a gonadal hormone in combination with a dopamine agonist such as bromocriptine, and optionally an ascorbate source. This method has a significant ability to stimulate enhanced lymphocyte function. Certain components used with the method may be combined into medicaments.
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31 Claims
- 1. A pharmaceutical composition useful in enhancing stimulated lymphocyte function comprising a dopamine agonist selected from the group consisting of bromoncriptine, lergotrile and pergolide or pharmaceutically acceptable salts thereof and a gonadal hormone selected from the group consisting of progestinic, androgenic or estrogenic hormones, in therapeutically effective amounts.
- 14. A method for stimulating enhanced lymphocyte function in human beings requiring such treatment comprising administering to said human being a dopamine agonist compound selected from the group consisting of bromocriptine, lergotrile and pergolide or pharmaceutically acceptable salts thereof and a gonadal hormone selected from the group consisting of progestinic, androgenic or estrogenic hormone in amounts sufficient to stimulate regulatory lymphocyte populations
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27. A method for stimulating enhanced lymphocyte function and somatotropin secretagogue effects in overweight human beings on a weight loss program comprising coadministering to said overweight human beings a dopamine agonist selected from the group consisting of bromocriptine, lergotrile and pergolide or pharmaceutically acceptable salts thereof, and an ascorbate source in an amount sufficient to stimulate regulatory lymphocyte populations to enhance somatotropin production.
Specification